Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amine Nourani"'
Autor:
Anne Rufiange, Eric Fournier, Wajid Waheed Bhat, Amine Nourani, Eric Paquet, Emmanuelle Gouot
Publikováno v:
Nucleic Acids Research
CK2 is an essential protein kinase implicated in various cellular processes. In this study, we address a potential role of this kinase in chromatin modulations associated with transcription. We found that CK2 depletion from yeast cells leads to repli
Autor:
Amine Nourani, Hongda Huang, Dinshaw J. Patel, Shoudeng Chen, Anne Rufiange, Kanagalaghatta R. Rajashankar
Publikováno v:
Genes & Development. 29:1326-1340
Cells use specific mechanisms such as histone chaperones to abrogate the inherent barrier that the nucleosome poses to transcribing polymerases. The current model postulates that nucleosomes can be transiently disrupted to accommodate passage of RNA
Autor:
Sandra Piquet, Julie Monnet-Saksouk, Amine Nourani, Valérie Côté, Julia M. Schulze, Dorine Rossetto, Michael S. Kobor, Anne-Lise Steunou, Nicolas Lacoste, Jacques Côté, Myriam Cramet, Alice Y. Wang
Publikováno v:
The EMBO Journal. 33:1397-1415
The NuA4 histone acetyltransferase complex is required for gene regulation, cell cycle progression, and DNA repair. Dissection of the 13-subunit complex reveals that the Eaf7 subunit bridges Eaf5 with Eaf3, a H3K36me3-binding chromodomain protein, an
Publikováno v:
Molecular Cell. 41(5):502-514
The many factors that control chromatin biology play key roles in essential nuclear functions like transcription, DNA damage response and repair, recombination, and replication and are critical for proper cell-cycle progression, stem cell renewal, di
Publikováno v:
Journal of Biological Chemistry. 283:27350-27354
Rtt106 is a histone chaperone that has been suggested to play a role in heterochromatin-mediated silencing in Saccharomyces cerevisiae. It interacts physically and functionally with the chromatin assembly factor-1 (CAF-1), which is associated with re
Autor:
Mohammed Altaf, Andréanne Auger, Yannick Doyon, Dominique Cronier, Jacques Côté, Rhea T. Utley, Amine Nourani, Luc Galarneau, Stéphane Allard
Publikováno v:
Molecular and Cellular Biology. 28:2257-2270
Eaf1 (for Esa1-associated factor 1) and Eaf2 have been identified as stable subunits of NuA4, a yeast histone H4/H2A acetyltransferase complex implicated in gene regulation and DNA repair. While both SWI3-ADA2-N-CoR-TF IIIB domain-containing proteins
Publikováno v:
Molecular Cell. 27(3):393-405
In yeast, histone H3/H4 exchange independent of replication is poorly understood. Here, we analyzed the deposition of histone H3 molecules, synthesized during G1, using a high-density microarray histone exchange assay. While we found that H3 exchange
Publikováno v:
The EMBO Journal. 23:2597-2607
The remodeling of the promoter chromatin structure is a key event for the induction of the PHO5 gene. Two DNA-binding proteins Pho2 and Pho4 are critical for this step. We found that the NuA4 histone acetyltransferase complex is essential for PHO5 tr
Autor:
Patrick A. Grant, Jerry L. Workman, Amine Nourani, Marilyn G. Pray-Grant, LeAnn J. Howe, Jacques Côté
Publikováno v:
Journal of Biological Chemistry. 278:19171-19175
The inhibitor-of-growth (ING) family of proteins was founded by human ING1, a tumor suppressor interacting with p53 in vivo and required for its function in transcription/apoptosis. There are five different ING genes in humans, three of which have be
Publikováno v:
Molecular and Cellular Biology. 21:7629-7640
The yeast NuA4 complex is a histone H4 and H2A acetyltransferase involved in transcription regulation and essential for cell cycle progression. We identify here a novel subunit of the complex, Yng2p, a plant homeodomain (PHD)-finger protein homologou