Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Amina Ait-Ammar"'
Autor:
Amina Ait-Ammar, Maxime Bellefroid, Fadoua Daouad, Valérie Martinelli, Jeanne Van Assche, Clémentine Wallet, Anthony Rodari, Marco De Rovere, Birthe Fahrenkrog, Christian Schwartz, Carine Van Lint, Virginie Gautier, Olivier Rohr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract HIV-1 latency generates reservoirs that prevent viral eradication by the current therapies. To find strategies toward an HIV cure, detailed understandings of the molecular mechanisms underlying establishment and persistence of the reservoirs
Externí odkaz:
https://doaj.org/article/fe46ec113a36484184b8fb43f3c5fa39
Autor:
Amina Ait-Ammar, Anna Kula, Gilles Darcis, Roxane Verdikt, Stephane De Wit, Virginie Gautier, Patrick W. G. Mallon, Alessandro Marcello, Olivier Rohr, Carine Van Lint
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
One of the most explored therapeutic approaches aimed at eradicating HIV-1 reservoirs is the “shock and kill” strategy which is based on HIV-1 reactivation in latently-infected cells (“shock” phase) while maintaining antiretroviral therapy (A
Externí odkaz:
https://doaj.org/article/0157bc9c5a4343be9f44024c01ba26bf
Autor:
Celine Marban, Faezeh Forouzanfar, Amina Ait-Ammar, Faiza Fahmi, Hala El Mekdad, Fadoua Daouad, Olivier Rohr, Christian Schwartz
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
One of the top research priorities of the international AIDS society by the action Towards an HIV Cure is the purge or the decrease of the pool of all latently infected cells. This strategy is based on reactivation of latently reservoirs (the shock)
Externí odkaz:
https://doaj.org/article/4559365b304f41deb3ce04bc66207d37
Autor:
Gilles Darcis, Anna Kula, Sophie Bouchat, Koh Fujinaga, Francis Corazza, Amina Ait-Ammar, Nadège Delacourt, Adeline Melard, Kabamba Kabeya, Caroline Vanhulle, Benoit Van Driessche, Jean-Stéphane Gatot, Thomas Cherrier, Luiz F Pianowski, Lucio Gama, Christian Schwartz, Jorge Vila, Arsène Burny, Nathan Clumeck, Michel Moutschen, Stéphane De Wit, B Matija Peterlin, Christine Rouzioux, Olivier Rohr, Carine Van Lint
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005063 (2015)
The persistence of latently infected cells in patients under combinatory antiretroviral therapy (cART) is a major hurdle to HIV-1 eradication. Strategies to purge these reservoirs are needed and activation of viral gene expression in latently infecte
Externí odkaz:
https://doaj.org/article/46911b3af13e4e1dbee7dd349246f43b
Autor:
Maxime Bellefroid, Anthony Rodari, Mathilde Galais, Peter H L Krijger, Sjoerd J D Tjalsma, Lorena Nestola, Estelle Plant, Erica S M Vos, Sara Cristinelli, Benoit Van Driessche, Caroline Vanhulle, Amina Ait-Ammar, Arsène Burny, Angela Ciuffi, Wouter de Laat, Carine Van Lint
Publikováno v:
Nucleic Acids Research, 50(6), 3190-3202. Oxford University Press
Bovine leukemia virus (BLV)-induced tumoral development is a multifactorial phenomenon that remains incompletely understood. Here, we highlight the critical role of the cellular CCCTC-binding factor (CTCF) both in the regulation of BLV transcriptiona
Autor:
Francis Corazza, Le Douce, Christian Schwartz, Van Lint C, Nestola L, Caroline Vanhulle, Pereira Bittencourt Passaes C, Amina Ait-Ammar, Avettand-Fenoel, Christine Rouzioux, François Fuks, Maryam Bendoumou, Ben Berkhout, Alexander O. Pasternak, Coca Valentina Necsoi, Sophie Bouchat, Gilles Darcis, Plant E, Rohr O, Gautier, De Wit S, Nadège Delacourt, Cicilionyte A, Asier Sáez-Cirión, Roxane Verdikt, Martin Bizet
The multiplicity, heterogeneity and dynamic nature of HIV-1 latency mechanisms are reflected in the current lack of functional cure for HIV-1 and in the various reported ex vivo potencies of latency- reversing agents. Here, we investigated the molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7dc9bbee89938bd9c60e62e54e1ca9
https://doi.org/10.1101/2021.06.15.448539
https://doi.org/10.1101/2021.06.15.448539
Autor:
Olivier Rohr, Van Lint C, Amina Ait-Ammar, De Rovere M, Clémentine Wallet, Christian Schwartz, Haitham Sobhy, Fadoua Daouad
Although BCL11b (B-cell lymphoma/leukemia 11B, CTIP2) is a well-known transcription repressor and tumor suppressor, its functions and cellular pathways are largely unknown. Here, we show that BCL11b interacts with RNA splicing/processing and nonsense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60a7bf88d5961d57ff93ae4aeb5bdb9
https://doi.org/10.1101/2020.11.05.369959
https://doi.org/10.1101/2020.11.05.369959
Autor:
Virginie Gautier, Maxime Bellefroid, Valérie Martinelli, Jeanne Van Assche, Birthe Fahrenkrog, Amina Ait-Ammar, Christian Schwartz, Clémentine Wallet, Fadoua Daouad, Carine Van Lint, Marco De Rovere, Olivier Rohr
HIV-1 latency generates reservoirs that prevent viral eradication by the current therapies. To find strategies toward an HIV cure, detailed understandings of the molecular mechanisms underlying establishment and persistence of the reservoirs are need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ad3a24a3aebfe04782886e127c2788
https://doi.org/10.1101/2020.04.28.066274
https://doi.org/10.1101/2020.04.28.066274
Autor:
Stéphane De Wit, Olivier Rohr, Anna Kula, Virginie Gautier, Patrick W. G. Mallon, Gilles Darcis, Roxane Verdikt, Carine Van Lint, Alessandro Marcello, Amina Ait-Ammar
Publikováno v:
Frontiers in microbiology, 10
Frontiers in Microbiology
Frontiers in Microbiology, Frontiers Media, 2020, 10, pp.3060. ⟨10.3389/fmicb.2019.03060⟩
Frontiers in Microbiology, Vol 10 (2020)
Frontiers in Microbiology
Frontiers in Microbiology, Frontiers Media, 2020, 10, pp.3060. ⟨10.3389/fmicb.2019.03060⟩
Frontiers in Microbiology, Vol 10 (2020)
One of the most explored therapeutic approaches aimed at eradicating HIV-1 reservoirs is the "shock and kill" strategy which is based on HIV-1 reactivation in latently-infected cells ("shock" phase) while maintaining antiretroviral therapy (ART) in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854ef7b9619f8a398fe78f38178d5621
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/303221
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/303221
Publikováno v:
Seminars in Immunopathology
Seminars in immunopathology, vol 42, iss 2
Seminars in immunopathology, vol 42, iss 2
Human immunodeficiency virus 1 (HIV-1) replicates through the integration of its viral DNA into the genome of human immune target cells. Chronically infected individuals thus carry a genomic burden of virus-derived sequences that persists through ant