Generic membrane spanning features endow IRE1α with responsiveness to membrane aberrancy

Autor: Kono, N, Amin-Wetzel, N, Ron, D

Altered cellular lipid composition activates the endoplasmic reticulum unfolded protein response (UPR) and UPR signaling effects important changes in lipid metabolism. Secondary effects on protein folding homeostasis likely contribute to UPR activati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbd81f3421030aad8fb040a33d025bd
https://www.repository.cam.ac.uk/handle/1810/267297

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Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells

Autor: Sekine, Y, Zyryanova, A, Crespillo-Casado, A, Amin-Wetzel, N, Harding, HP, Ron, D

The eukaryotic translation initiation factor eIF2B promotes mRNA translation as a guanine nucleotide exchange factor (GEF) for translation initiation factor 2 (eIF2). Endoplasmic reticulum (ER) stress-mediated activation of the kinase PERK and the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22b6c35bb4330036d2c55abd1f1d6c70

The URX oxygen-sensing neurons in C. elegan s are ciliated.

Autor: Kazatskaya A; Brandeis University, Waltham, MA 02454., Yuan L; Brandeis University, Waltham, MA 02454., Amin-Wetzel N; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria., Philbrook A; Brandeis University, Waltham, MA 02454., de Bono M; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria., Sengupta P; Brandeis University, Waltham, MA 02454.

Publikováno v: MicroPublication biology [MicroPubl Biol] 2020 Sep 20; Vol. 2020. Date of Electronic Publication: 2020 Sep 20.