Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Amin S Ghabrial"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007146 (2018)
During sprouting angiogenesis in the vertebrate vascular system, and primary branching in the Drosophila tracheal system, specialized tip cells direct branch outgrowth and network formation. When tip cells lumenize, they form subcellular (seamless) t
Externí odkaz:
https://doaj.org/article/4fab9ef00b764468bc967ed3684e3017
Publikováno v:
PLoS Genetics, Vol 7, Iss 7, p e1002087 (2011)
Many signaling proteins and transcription factors that induce and pattern organs have been identified, but relatively few of the downstream effectors that execute morphogenesis programs. Because such morphogenesis genes may function in many organs an
Externí odkaz:
https://doaj.org/article/995fb681d5c34b5d9d3ad02063e700f6
Publikováno v:
Development. 149
Larval terminal cells of the Drosophila tracheal system generate extensive branched tubes, requiring a huge increase in apical membrane. We discovered that terminal cells compromised for apical membrane expansion – mTOR-vATPase axis and apical pola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21833616df6825692c681c4fe5c4cb8
https://doi.org/10.1242/dev.200908
https://doi.org/10.1242/dev.200908
Publikováno v:
Dev Biol
The terminal cells of the larval Drosophila tracheal system extend dozens of branched cellular processes, most of which become hollow intracellular tubes that support gas exchange with internal tissues. Previously, we undertook a forward genetic mosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0792221c7a5a21a92aa479b7fd78bd0e
https://doi.org/10.1016/j.ydbio.2019.02.001
https://doi.org/10.1016/j.ydbio.2019.02.001
Dissection of the Role of CCM Genes in Tubulogenesis Using the Drosophila Tracheal System as a Model
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2152
Embryos deficient for an essential gene may show complex phenotypes that reflect pleiotropic functions and non-cell-autonomous requirements for the encoded protein. The generation of mosaic animals, where most cells are wild type, but a few cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b96958f570d8b2f8ed4058aa8fad01c3
https://pubmed.ncbi.nlm.nih.gov/32524553
https://pubmed.ncbi.nlm.nih.gov/32524553
Dissection of the Role of CCM Genes in Tubulogenesis Using the Drosophila Tracheal System as a Model
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606391
Embryos deficient for an essential gene may show complex phenotypes that reflect pleiotropic functions and non-cell-autonomous requirements for the encoded protein. The generation of mosaic animals, where most cells are wild type, but a few cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b12a2ed07a5215d21ebcdbdfbff7f03
https://doi.org/10.1007/978-1-0716-0640-7_14
https://doi.org/10.1007/978-1-0716-0640-7_14
Autor:
Kieran F. Harvey, Xiaomeng Zhang, Yanjun Song, Marta Gomez, Weijie Liu, Carole L.C. Poon, Alexander Hergovich, Amin S. Ghabrial, Yavuz Kulaberoglu, Alexey Veraksa, Wenjian Xu
Hippo-like pathways are ancient signalling modules first identified in yeasts. The best-defined metazoan module forms the core of the Hippo pathway, which regulates organ size and cell fate. Hippo-like kinase modules consist of a Sterile 20-like kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166addc075dd726832d56a434c30a395
https://europepmc.org/articles/PMC6281297/
https://europepmc.org/articles/PMC6281297/
Autor:
Amin S. Ghabrial
Publikováno v:
Proceedings of the National Academy of Sciences. 116:24388-24389
The last decade has seen an explosion of research on exosomes, small (30 to 100 nm) vesicles that are trafficked to the extracellular environment by the fusion of the multivesicular body to the plasma membrane (1, 2). Exosomes arise from endosomal mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c06ba900d5363c60f012ed22ef0f002
https://doi.org/10.1073/pnas.1918086116
https://doi.org/10.1073/pnas.1918086116
Autor:
Deanne Francis, Amin S. Ghabrial
Publikováno v:
Development. 142:2048-2057
Tubes are essential for nutrient transport and gas exchange in multicellular eukaryotes, but how connections between different tube types are maintained over time is unknown. In the Drosophila tracheal system, mutations in oak gall (okg) and conjoine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e1c5c31ef6309962e67c6ad64bfb6a
https://doi.org/10.1242/dev.119602
https://doi.org/10.1242/dev.119602