Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Amin Mottahedin"'
Autor:
Gisela Nilsson, Amin Mottahedin, Aura Zelco, Volker M. Lauschke, C. Joakim Ek, Juan Song, Maryam Ardalan, Sha Hua, Xiaoli Zhang, Carina Mallard, Henrik Hagberg, Jianmei W. Leavenworth, Xiaoyang Wang
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 8, Pp 336-353 (2023)
Abstract Abnormal myelination underlies the pathology of white matter diseases such as preterm white matter injury and multiple sclerosis. Osteopontin (OPN) has been suggested to play a role in myelination. Murine OPN mRNA is translated into a secret
Externí odkaz:
https://doaj.org/article/3051a4998a3a476e9b6f2a2f9b0668b3
Autor:
Amin Mottahedin, Hiran A. Prag, Andreas Dannhorn, Richard Mair, Christina Schmidt, Ming Yang, Annabel Sorby-Adams, Jordan J. Lee, Nils Burger, Duvaraka Kulaveerasingam, Margaret M. Huang, Stefano Pluchino, Luca Peruzzotti-Jametti, Richard Goodwin, Christian Frezza, Michael P. Murphy, Thomas Krieg
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102600- (2023)
Current treatments for acute ischemic stroke aim to reinstate a normal perfusion in the ischemic territory but can also cause significant ischemia-reperfusion (IR) injury. Previous data in experimental models of stroke show that ischemia leads to the
Externí odkaz:
https://doaj.org/article/41b646b7b62b4c0d9fe37775e8348c63
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Ischemic stroke induces the activation and recruitment of peripheral leukocytes to the injured brain. These cells can infiltrate the brain through multiple routes, either by penetrating blood–brain barrier or via blood–CSF bar
Externí odkaz:
https://doaj.org/article/3fcf7e253167454c9a44212fd978b08f
Autor:
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R. Bridges, Hiran A. Prag, Daniel N. Grba, Carlo Viscomi, Andrew M. James, Amin Mottahedin, Thomas Krieg, Michael P. Murphy, Judy Hirst
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Reactive oxygen species (ROS) production by reverse electron transfer (RET) through complex I is thought to cause tissue damage from heart attacks. Here, the authors combine in vivo work with biochemical and cryo-EM analyses to characterize the effec
Externí odkaz:
https://doaj.org/article/1317dd8d29fd49259db11814845c32ea
Autor:
Amin Mottahedin, Sandrine Blondel, Joakim Ek, Anna-Lena Leverin, Pernilla Svedin, Henrik Hagberg, Carina Mallard, Jean-Francois Ghersi-Egea, Nathalie Strazielle
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract The etiology of neurological impairments associated with prematurity and other perinatal complications often involves an infectious or pro-inflammatory component. The use of antioxidant molecules have proved useful to protect the neonatal br
Externí odkaz:
https://doaj.org/article/d3a2bef21caf4c7fac7e925810b8ce7c
Autor:
Peter L. P. Smith, Amin Mottahedin, Pernilla Svedin, Carl-Johan Mohn, Henrik Hagberg, Joakim Ek, Carina Mallard
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract Background Neonatal brain injury is increasingly understood to be linked to inflammatory processes that involve specialised CNS and peripheral immune interactions. However, the role of peripheral myeloid cells in neonatal hypoxic-ischemic (H
Externí odkaz:
https://doaj.org/article/06d2460ba5b8494498d221c9107ff981
Autor:
Raul Chavez-Valdez, Amin Mottahedin, Linnea Stridh, Tracylyn R. Yellowhair, Lauren L. Jantzie, Frances J. Northington, Carina Mallard
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Toll-like receptor (TLR)3 activation during the neonatal period produces responses linked to the origins of neuropsychiatric disorders. Although there is sexual dimorphism in neuropsychiatric disorders, it is unknown if brain responses to TLR3 activa
Externí odkaz:
https://doaj.org/article/cb6ccd6aaa3044deb45f2e4cd322c615
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The brain is a plastic organ where both the intrinsic CNS milieu and extrinsic cues play important roles in shaping and wiring neural connections. The perinatal period constitutes a critical time in central nervous system development with extensive r
Externí odkaz:
https://doaj.org/article/06cb3fa47fb64d7a807a914e6333bba1
Autor:
Mehdi R M Bidokhti, Karin Ullman, Trine H Jensen, Mariann Chriél, Amin Mottahedin, Muhammad Munir, Anna Maria Andersson, Olivier Detournay, Anne Sofie Hammer, Claudia Baule
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82978 (2013)
Astroviruses are becoming a growing concern in veterinary and public health. To date there are no registered vaccines against astrovirus-induced disease, mostly due to the difficulty to cultivate astroviruses to high titer for vaccine development usi
Externí odkaz:
https://doaj.org/article/f4bb8b1e9cf2419b9072f6c2f18b8a00
Autor:
Richard C. Hartley, Marta Loureiro-López, Shujing Ding, Sabine Arndt, Michael P. Murphy, John F. Mulvey, Nils Burger, Abigail A.I. Norman, Kurt Hoogewijs, Olga Sauchanka, Andrew M. James, Ian M. Fearnley, Thomas Krieg, Amin Mottahedin
Publikováno v:
Cell chemical biology. 29(4)
Mammalian complex I can adopt catalytically active (A-) or deactive (D-) states. A defining feature of the reversible transition between these two defined states is thought to be exposure of the ND3 subunit Cys39 residue in the D-state and its occlus