Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Amilcar Falcão"'
Autor:
Kimberly R. Byrnes, Richard J. Barohn, Robert C. Griggs, Brian C. Healy, Amanda M. VanDenburgh, Jon Wagg, David J. Loane, Carlos Lopes, Guy J. Buckle, Mark S. Guyer, Noel James Cusack, Amilcar Falcão, Susan A. Gauthier, S. Hua, Michael P. McDermott, Howard L. Weiner, James Stankiewicz, Robyn Guinn, S. Abu-Shakra, M. Vaz-da-Silva, Rebecca A. Betensky, Mark R. Hurtt, Leonel Torrão, Peter Meltzer, Joana Maia, Raquel Costa, Laura Herbelin, José Rocha, Rita Machado, Tatiana Khariton, Mohit Neema, Alan I. Faden, Rui Coelho, Lyndon C. Wright, Zachary D. Guss, Bonnie I. Glanz, Davette Behrens, Ahdeah Pajoohesh-Ganji, Kimberly A. Hart, Jamie Driscoll, Simon Katner, Bruce J. Aungst, Fatta B. Nahab, Ashish Arora, Jason G. Guss, Foster Brown, Antonio Albino-Teixeira, Dominik S. Meier, Samia J. Khoury, M. F. Brin, Ingrid Li, Noel J. Cusack, Charles R.G. Guttmann, Christine Thorne, Patrício Soares-da-Silva, Svetlana Egorova, Mark Hallett, Bruce Solomon, Manasee V. Shah, Lata Venkatarangan, Zsuzsanna Liptak, Candace Rohde, Teresa G. Nunes, F. C. Beddingfield, Barbara E. Herr, Yong Yao, Rohit Bakshi, A. I. Loureiro, Luis Almeida, John Torchia, Linda S. Brady, Bogdan A. Stoica, Loretta Wittevrongel
Publikováno v:
Neurotherapeutics. 5:490-495
Background and Objective An assessment of clinically important change is useful in interpreting clinical trial outcomes. The 4-point Ashworth Scale (AS) is a widely accepted measure of muscle tone, and the 9-point Physician Global Assessment Score (P
Publikováno v:
Life, Vol 13, Iss 12, p 2323 (2023)
Consumers today seek safe functional foods with proven health-promoting properties. Current evidence shows that a healthy diet can effectively alleviate oxidative stress levels and reduce inflammatory markers, thereby preventing the occurrence of man
Externí odkaz:
https://doaj.org/article/98abce727b724c15bf95c25fe6649e31
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 11, Iss 4, Pp 405-421 (2021)
The new antiepileptic drugs perampanel, retigabine, rufinamide and stiripentol have been recently approved for different epilepsy types. Being them an innovation in the antiepileptics armamentarium, a lot of investigations regarding their pharmacolog
Externí odkaz:
https://doaj.org/article/005c87bf5151474baf6f7ff59838815f
Autor:
Ivanna Hrynchak, Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Sérgio J. C. do Carmo, Roxana Cornoiu, Amílcar Falcão, Dana Niculae, Antero J. Abrunhosa
Publikováno v:
Molecules, Vol 28, Iss 12, p 4670 (2023)
Antibody and nanobody-based copper-64 radiopharmaceuticals are increasingly being proposed as theranostic tools in multiple human diseases. While the production of copper-64 using solid targets has been established for many years, its use is limited
Externí odkaz:
https://doaj.org/article/2baf189e8d844e77878f52becd51db8c
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1641 (2023)
Stiripentol (STP) is a new-generation antiepileptic only available for oral administration. However, it is extremely unstable in acidic environments and undergoes gastrointestinal slow and incomplete dissolution. Thus, STP intranasal (IN) administrat
Externí odkaz:
https://doaj.org/article/3c48b6aa943541bf8a17a689d8e570f4
Autor:
Rui Silva, Helena Colom, Joana Bicker, Anabela Almeida, Ana Silva, Francisco Sales, Isabel Santana, Amílcar Falcão, Ana Fortuna
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1704 (2023)
Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of
Externí odkaz:
https://doaj.org/article/1a499d849c894123a713d50ccc2d2018
Autor:
Ana C. Gonçalves, Ana R. Nunes, Sara Meirinho, Miguel Ayuso-Calles, Rocío Roca-Couso, Raúl Rivas, Amílcar Falcão, Gilberto Alves, Luís R. Silva, José David Flores-Félix
Publikováno v:
Applied Sciences, Vol 13, Iss 10, p 6348 (2023)
(1) Background: Nowadays, special attention has been paid to red and purple fruits, including blueberries and sweet cherries, since they are highly attractive to consumers due to their organoleptic properties, standing out due to their vibrant red an
Externí odkaz:
https://doaj.org/article/b9576c12e7d04ac79177c462c109c7ec
Autor:
Ângela C. B. Neves, Ivanna Hrynchak, Inês Fonseca, Vítor H. P. Alves, Mariette M. Pereira, Amílcar Falcão, Antero J. Abrunhosa
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-19 (2021)
Abstract The neurotracer 6-[18F] FDOPA has been, for many years, a powerful tool in PET imaging of neuropsychiatric diseases, movement disorders and brain malignancies. More recently, it also demonstrated good results in the diagnosis of other malign
Externí odkaz:
https://doaj.org/article/1c01afc15ef04c6397a64225cdc1ab92
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 373 (2023)
Amikacin is the antibiotic of choice for the treatment of Gram-negative infections, namely, those in neutropenic oncology patients. No populational pharmacokinetic studies are currently available reporting amikacin pharmacokinetics in neutropenic onc
Externí odkaz:
https://doaj.org/article/9456b2adce564e09811156e7448e90ae
Autor:
Soraia Silva, Joana Bicker, Carla Fonseca, Nuno R. Ferreira, Carla Vitorino, Gilberto Alves, Amílcar Falcão, Ana Fortuna
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Depression is a common mental disorder. Its treatment with selective serotonin reuptake inhibitors (SSRIs) is effective only in a fraction of patients, and pharmacoresistance is increasing steadily. Intranasal (IN) drug delivery to the brain stands o
Externí odkaz:
https://doaj.org/article/c555d32d8b50493e9adac2c1c0e8ed7d