Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amiet R. Chhatta"'
Autor:
Rob C. Hoeben, Amiet R. Chhatta, Maria Themeli, Edwin de Wilt, Hester Boersma, Aïda Shahrabi Farahani, Martijn Cordes, Henk-Jan Prins, Bart Vandekerckhove, Frank J. T. Staal, Harald Mikkers, Mirjam van der Burg
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 300-311 (2020)
STEM CELL REPORTS
Stem Cell Reports
Themeli, M, Chhatta, A, Boersma, H, Prins, H J, Cordes, M, de Wilt, E, Farahani, A S, Vandekerckhove, B, van der Burg, M, Hoeben, R C, Staal, F J T & Mikkers, H M M 2020, ' iPSC-Based Modeling of RAG2 Severe Combined Immunodeficiency Reveals Multiple T Cell Developmental Arrests ', Stem Cell Reports, vol. 14, no. 2, pp. 300-311 . https://doi.org/10.1016/j.stemcr.2019.12.010
Stem Cell Reports, 14(2), 300-311. CELL PRESS
Stem Cell Reports, 14(2), 300-311. Cell Press
STEM CELL REPORTS
Stem Cell Reports
Themeli, M, Chhatta, A, Boersma, H, Prins, H J, Cordes, M, de Wilt, E, Farahani, A S, Vandekerckhove, B, van der Burg, M, Hoeben, R C, Staal, F J T & Mikkers, H M M 2020, ' iPSC-Based Modeling of RAG2 Severe Combined Immunodeficiency Reveals Multiple T Cell Developmental Arrests ', Stem Cell Reports, vol. 14, no. 2, pp. 300-311 . https://doi.org/10.1016/j.stemcr.2019.12.010
Stem Cell Reports, 14(2), 300-311. CELL PRESS
Stem Cell Reports, 14(2), 300-311. Cell Press
Summary RAG2 severe combined immune deficiency (RAG2-SCID) is a lethal disorder caused by the absence of functional T and B cells due to a differentiation block. Here, we generated induced pluripotent stem cells (iPSCs) from a RAG2-SCID patient to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14e958e4b23f7f4aa64dd4958988485
https://hdl.handle.net/1887/3182641
https://hdl.handle.net/1887/3182641
Publikováno v:
Journal of Immunology and Regenerative Medicine. 14:100052
The thymus plays a crucial role in adaptive immunity through the regulation of T cell development. Thymus dysfunction can have a number of implications, such as increased predisposition to infection and autoimmunity, age-related reduced response to v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0f93e0da330079f6a4603d2c4fa98c
https://doi.org/10.1016/j.regen.2021.100052
https://doi.org/10.1016/j.regen.2021.100052
Autor:
Sjef Verbeek, Frank J. T. Staal, Daniela C.F. Salvatori, Cor Breukel, Jolanda. J. D. de Roo, Harald Mikkers, Margot M. Linssen, Sandra A. Vloemans, Amiet R. Chhatta
Publikováno v:
genesis, 55(10)
The canonical Wnt signalling pathway has been implicated in organogenesis and self-renewal of essentially all stem cell systems. In vivo reporter systems are crucial to assess the role of Wnt signalling in the biology and pathology of stem cell syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3233f775f0ae6e5cc79b2bb3906735f5
http://hdl.handle.net/1887/115711
http://hdl.handle.net/1887/115711
Publikováno v:
Experimental Hematology, 44(6), 451-457
The Wnt signaling pathway is an evolutionary conserved pathway that is involved in the development of almost every organ system in the body and provides self-renewal signals for most, if not all, adult stem cell systems. In recent years, this pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9071b65511b853ef14be19d9cf20af6c
https://pubmed.ncbi.nlm.nih.gov/27016274
https://pubmed.ncbi.nlm.nih.gov/27016274
Autor:
Amiet R. Chhatta, Willem E. Fibbe, Karin Pike-Overzet, Françoise Carlotti, Frank J. T. Staal, Daniela C.F. Salvatori, Maaike Hanegraaf, Martijn Cordes, Jan J. Cornelissen, Tom Cupedo, Harald Mikkers, Sandra A. Vloemans, Rob C. Hoeben
Publikováno v:
Journal of Allergy and Clinical Immunology, 144(5), 1416
Journal of Allergy and Clinical Immunology, 144(5), 1416-+. Mosby Inc.
Journal of Allergy and Clinical Immunology, 144(5), 1416-+. Mosby Inc.
A proper functional thymus is required for generation of T cell–mediated immunity. This is dramatically illustrated by patients lacking a thymus, such as children with complete DiGeorge syndrome, which is fatal if left untreated.1-3 Therapeutic opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468085f43577c943996bbc684372d176
https://doi.org/10.1016/j.jaci.2019.05.042
https://doi.org/10.1016/j.jaci.2019.05.042
Autor:
Esther H. Lips, Amiet R. Chhatta, Tom van Wezel, Marjo van Puijenbroek, Nisha Gupta, Anne-Marie Cleton-Jansen, Hans Morreau, Ronald van Eijk, Rolf H. A. M. Vossen
Publikováno v:
The Journal of Molecular Diagnostics. 12:27-34
Kirsten RAS (KRAS) is a small GTPase that plays a key role in Ras/mitogen-activated protein kinase signaling; somatic mutations in KRAS are frequently found in many cancers. The most common KRAS mutations result in a constitutively active protein. Ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b815f1c1e78ad760a6f30a419158958
https://doi.org/10.2353/jmoldx.2010.090028
https://doi.org/10.2353/jmoldx.2010.090028
Autor:
de Roo, Jolanda. J. D., Breukel, Cor, Chhatta, Amiet R., Linssen, Margot M., Vloemans, Sandra A., Salvatori, Daniela, Mikkers, Harald M. M., Verbeek, Sjef J., Staal, Frank J.T.
Publikováno v:
Genesis: The Journal of Genetics & Development; Oct2017, Vol. 55 Issue 10, pn/a-N.PAG, 7p