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pro vyhledávání: '"Amiel Yanai"'
Autor:
Grace Swickley, Yehoshua Bloch, Lidor Malka, Adi Meiri, Sharon Noy-Lotan, Amiel Yanai, Hannah Tamary, Benny Motro
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Congenital dyserythropoietic anemia type I (CDA I), is an autosomal recessive disease with macrocytic anemia in which erythroid precursors in the bone marrow exhibit pathognomonic abnormalities including spongy heterochromatin and
Externí odkaz:
https://doaj.org/article/6e117771ef5c441294be37568e85ff4e
Autor:
Benny Motro, Lidor Malka, Adi Meiri, Yehoshua Bloch, Hannah Tamary, Amiel Yanai, Grace Swickley, Sharon Noy-Lotan
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-12 (2020)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background Congenital dyserythropoietic anemia type I (CDA I), is an autosomal recessive disease with macrocytic anemia in which erythroid precursors in the bone marrow exhibit pathognomonic abnormalities including spongy heterochromatin and chromati
Publikováno v:
DNA and Cell Biology. 18:593-603
The members of the Ipl1-aurora like kinase (IARK) subfamily are conserved serine/threonine kinases that play a key role in the control of chromosome segregation, centrosome separation, and cytokinesis from yeast to mammals. We report on the isolation
Publikováno v:
Gene. 234:127-137
The Aspergillus NIMA kinase plays a key role in controlling entrance into mitosis, and recent evidence suggests that mammalian NIMA-related kinases perform similar functions. We report here the cloning of the mouse nek3 and nek4 genes. Mouse nek3 is
Publikováno v:
Oncogene. 16:1813-1823
NIMA protein kinase is a major regulator of progression into mitosis in Aspergillus nidulans. Dominant negative forms of NIMA protein prevent entrance into mitosis in HeLa cells, suggesting that mammals have a similar pathway. We have reported previo
Publikováno v:
Oncogene. 14(24)
A novel murine gene, designated ayk1, which encodes a putative serine/threonine kinase has been cloned and characterized. The predicted catalytic domain of the protein is highly similar to that of Drosophila aurora (62.9% identity), and to that of Sa
Publikováno v:
Proceedings of the National Academy of Sciences. 101:5313-5314
The genomes of many species, including man, have been laid bare with hundreds of known and thousands of unknown genes. A major challenge in present day biology is to decipher the molecular function of the unknown genes. Gene knockout by homologous re