Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Amiee M. W. Handy"'
Autor:
Philip LoGrasso, Thomas D. Bannister, Yen Ting Chen, Wayne Grant, Thomas Schröter, Xingang Fang, Yangbo Feng, Tomas Vojkovsky, Amiee M. W. Handy, Jennifer Pocas
Publikováno v:
Med. Chem. Commun.. 2:73-75
Rho kinase (ROCK) is currently investigated as a target for various diseases such as glaucoma and spinal cord injury. Herein, we report the asymmetric synthesis of chroman 1, a highly potent ROCK inhibitor, and its analogs. The inhibitory properties