Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Amie K, Waller"'
Autor:
Amber R Philp, Carolina R Reyes, Josselyne Mansilla, Amar Sharma, Chao Zhao, Carlos Valenzuela-Krugmann, Khalil S Rawji, Ginez A Gonzalez Martinez, Penelope Dimas, Bryan Hinrichsen, César Ulloa-Leal, Amie K Waller, Diana M Bessa de Sousa, Maite A Castro, Ludwig Aigner, Pamela Ehrenfeld, Maria Elena Silva, Ilias Kazanis, Cedric Ghevaert, Robin JM Franklin, Francisco J Rivera
Publikováno v:
eLife, Vol 12 (2024)
Revealing unknown cues that regulate oligodendrocyte progenitor cell (OPC) function in remyelination is important to optimise the development of regenerative therapies for multiple sclerosis (MS). Platelets are present in chronic non-remyelinated les
Externí odkaz:
https://doaj.org/article/7461240c98c34149be24d14e2b4bf8cc
Autor:
Xiaojuan Zhao, Dominic Alibhai, Tony G. Walsh, Nathalie Tarassova, Maximilian Englert, Semra Z. Birol, Yong Li, Christopher M. Williams, Chris R. Neal, Philipp Burkard, Stephen J. Cross, Elizabeth W. Aitken, Amie K. Waller, José Ballester Beltrán, Peter W. Gunning, Edna C. Hardeman, Ejaife O. Agbani, Bernhard Nieswandt, Ingeborg Hers, Cedric Ghevaert, Alastair W. Poole
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Platelets, small hemostatic blood cells, are derived from megakaryocytes. Both bone marrow and lung are principal sites of thrombopoiesis although underlying mechanisms remain unclear. Outside the body, however, our ability to generate large
Externí odkaz:
https://doaj.org/article/b34379c46b594e3991173e9d3c71b0ac
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1237 (2022)
Infection by Staphylococcus aureus is the leading cause of infective endocarditis (IE). Activation of platelets by this pathogen results in their aggregation and thrombus formation which are considered to be important steps in the development and pat
Externí odkaz:
https://doaj.org/article/0c46ad6bf85c400b9b6813bf40f5d8c0
Autor:
Cavan Bennett, Moyra Lawrence, Jose A. Guerrero, Simon Stritt, Amie K. Waller, Yahui Yan, Richard W. Mifsud, Jose Ballester-Beltrán, Ayesha Baig, Annett Mueller, Louisa Mayer, James Warland, Christopher J. Penkett, Parsa Akbari, Thomas Moreau, Amanda L. Evans, Souradip Mookerjee, Gary J. Hoffman, Kourosh Saeb-Parsy, David J. Adams, Amber L. Couzens, Markus Bender, Wendy N. Erber, Bernhard Nieswandt, Randy J. Read, Cedric Ghevaert
Publikováno v:
Blood. 139:2227-2239
The process of platelet production has so far been understood to be a 2-stage process: megakaryocyte maturation from hematopoietic stem cells followed by proplatelet formation, with each phase regulating the peripheral blood platelet count. Proplatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e0ff77a46b889fca56887fe7308296
https://doi.org/10.1182/blood.2021013113
https://doi.org/10.1182/blood.2021013113
Autor:
Juan Li, Matthew J. Williams, Hyun Jung Park, Hugo P. Bastos, Xiaonan Wang, Daniel Prins, Nicola K. Wilson, Carys Johnson, Kendig Sham, Michelle Wantoch, Sam Watcham, Sarah J. Kinston, Dean C. Pask, Tina L. Hamilton, Rachel Sneade, Amie K. Waller, Cedric Ghevaert, George S. Vassiliou, Elisa Laurenti, David G. Kent, Berthold Göttgens, Anthony R. Green
Publikováno v:
Blood. 140(14)
Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal downstream mediator of interferon (IFN) signaling and is required for IFN-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b3473e03ba7545c979340a928a1812
https://pubmed.ncbi.nlm.nih.gov/35767701
https://pubmed.ncbi.nlm.nih.gov/35767701
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 204:981-988
Platelet transfusions, which are currently totally dependent on altruistic donations, are absolutely necessary to the treatment of patients with thrombocytopenia following trauma, surgery or other pathologies (especially malignancies). Producing plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed9e7cd58e760e72684bd49803390d2
https://doi.org/10.1016/j.banm.2020.10.004
https://doi.org/10.1016/j.banm.2020.10.004
Autor:
Souradip Mookerjee, Amie K. Waller, Thomas Moreau, Daniel Howard, Jonathan N. Thon, Joseph E. Italiano, Moyra Lawrence, Annie K Burton, Lehmann Marcus, Cedric Ghevaert, Holly R. Foster, Amanda Dalby, Jorge Valdez, Amanda L. Evans, Momal Taimoor
Publikováno v:
Blood Adv
The production of in vitro–derived platelets has great potential for transfusion medicine. Here, we build on our experience in the forward programming (FoP) of human pluripotent stem cells (hPSCs) to megakaryocytes (MKs) and address several aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783281999e46c0ce285b2cc0429d5ffe
https://pubmed.ncbi.nlm.nih.gov/33843988
https://pubmed.ncbi.nlm.nih.gov/33843988
Autor:
Cristina González-Gómez, Claudia Korn, Randall S. Johnson, Carlos López-Otín, Justyna Rak, Amie K. Waller, William Vainchenker, Fawzia Louache, Monika Wittner, Claus Nerlov, Alberto del Monte, Simón Méndez-Ferrer, Raquel del Toro, José Rivera-Torres, Ya-Hsuan Ho, Cedric Ghevaert, David Macías, Holly R. Foster, Vicente Andrés, Andrés García-García
Publikováno v:
Scopus
Cell Stem Cell
Cell Stem Cell, Cambridge, MA : Cell Press, 2019, 25 (3), pp.407-418.e6. ⟨10.1016/j.stem.2019.06.007⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
RUO. Repositorio Institucional de la Universidad de Oviedo
Cell Stem Cell
Cell Stem Cell, Cambridge, MA : Cell Press, 2019, 25 (3), pp.407-418.e6. ⟨10.1016/j.stem.2019.06.007⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
RUO. Repositorio Institucional de la Universidad de Oviedo
Hematopoietic stem cells (HSCs) residing in the bone marrow (BM) accumulate during aging but are functionally impaired. However, the role of HSC-intrinsic and -extrinsic aging mechanisms remains debated. Megakaryocytes promote quiescence of neighbori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b31202d9c1316867a32ace915dd6f8c
http://hdl.handle.net/10651/53777
http://hdl.handle.net/10651/53777
Autor:
Jonathan M. Gibbins, Tanya Sage, Thomas Carr, Simon R. Clarke, Christopher Kumar, Amie K. Waller
Publikováno v:
The Journal of Infectious Diseases
Impaired healing is common in wounds infected with the major human pathogen Staphylococcus aureus, although the underlying mechanisms are poorly understood. Here, we show that S.aureus lipoteichoic acid (LTA) inhibits platelet\ud aggregation caused b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b9f404d9ff7376e1c91e2dd129a822
http://europepmc.org/articles/PMC3836464
http://europepmc.org/articles/PMC3836464
Autor:
Raquel del Toro, Ya-Hsuan Ho, Andrés García-García, Holly R. Foster, Carlos López-Otín, Claudia Korn, Claus Nerlov, Randall S. Johnson, Lorena Arranz, Simón Méndez-Ferrer, Radek C. Skoda, Justyna Rak, Monika Wittner, Ronny Nienhold, Fawzia Louache, José Rivera-Torres, David Macías, Cedric Ghevaert, Amie K. Waller, William Vainchenker, Vicente Andrés, Cristina González-Gómez, Lucia Kubovcakova
Publikováno v:
Blood. 132:3842-3842
Background: BM HSC accumulate during aging but are functionally impaired; however, it remains debated whether this aging results from HSC-intrinsic and/or -extrinsic mechanisms. Myeloid malignancies are more frequent in the elderly, but whether the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd5ab8cd5b9dbd227d26a71dcce15f42
https://doi.org/10.1182/blood-2018-99-116015
https://doi.org/10.1182/blood-2018-99-116015