Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ami Tamir"'
Autor:
Ewa Cendrowicz, Lisa Jacob, Shirley Greenwald, Ami Tamir, Iris Pecker, Rinat Tabakman, Lucy Ghantous, Liat Tamir, Roy Kahn, Jasmine Avichzer, Alexandra Aronin, Shira Amsili, Elina Zorde-Khvalevsky, Yosi Gozlan, Martijn Vlaming, Gerwin Huls, Tom van Meerten, Michal Elhalel Dranitzki, Adam Foley-Comer, Yaron Pereg, Amnon Peled, Ayelet Chajut, Edwin Bremer
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Treatment of Diffuse Large B Cell Lymphoma (DLBCL) patients with rituximab and the CHOP treatment regimen is associated with frequent intrinsic and acquired resistance. However, treatment with a CD47 monoclonal antibody in combina
Externí odkaz:
https://doaj.org/article/88f427a2882642b7b2f32986f378f0e2
Autor:
Shirley Greenwald, Ayelet Chajut, Alexandra Aronin, Amnon Peled, Matthew Weber, Ami Tamir, Iris Pecker, Rinat Tabakman, Lucy Ganthous, Liat Tamir, Roy Kahn, Jasmine Avichzer, Elina Zorde-Khvalevsky, Michal Michal Elhalel Dranitzki, Adam Foley-Comer, Mark Tykocinski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/9d1d813fb3514e5b91af359675727c2a
Autor:
Matthew P. Weber, Elina Zorde-Khvalevsky, Amnon Peled, Adam Foley-Comer, Ami Tamir, Ayelet Chajut, Lucy Ganthous, Alexandra Aronin, Rinat Tabakman, Shirley Greenwald, Jasmine Avichzer, Roy Kahn, Mark L. Tykocinski, Iris Pecker, Liat Ben Gigi Tamir, Michal Michal Elhalel Dranitzki
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTIGIT, an inhibitory immune checkpoint, is a target of interest for immuno-oncology combination therapies. TIGIT is part of a complex molecular network containing four receptors (DNAM1, TIGIT, PVRIG and CD96) and two ligands (PVR and PVRL2)
Autor:
Amnon Peled, Ami Tamir, Ayelet Chajut, Ewa Cendrowicz, Yaron Pereg, Edwin Bremer, Lisa Jacob, Gerwin Huls, Shirley Greenwald, Yosi Gozlan, Adam Foley-Comer
Publikováno v:
Blood. 136:19-20
The mainstay of treatment for Diffuse Large B cell Lymphoma (DLBCL) is conventional chemotherapy combined with anti-CD20 monoclonal antibody rituximab (RTX). However, a subset of patients is refractory to treatment and between 20 to 50% of patients w
Autor:
Ami Tamir, Adam Foley-Comer, Michal Dranitzki-Elhalel, Yaron Pereg, Shira Amsili, Amnon Peled, Alexandra Aronin, Shirley Greenwald, Ayelet Chajut, Liat Ben-gigi-Tamir, Susan Hilgendorf, Yehudith Sagiv, Iris Pecker, Yosi Gozlan, Edwin Bremer
Publikováno v:
Cancer Immunology Research. 7:A076-A076
Background: The (re)activation of anticancer innate and adaptive immunity is at the forefront of developments in cancer therapy. Here, we report on a new immunotherapeutic fusion protein, termed Dual Signaling Protein 107 (DSP107). DSP107 was designe
Autor:
Jacob Golenser, Noah Isakov, Amnon Altman, Ariel Ohayon, Yaakov Pollack, Rosa Sinay, Ami Tamir
Publikováno v:
Infection and Immunity. 78:4195-4205
Protein kinase C θ (PKCθ) functions as a core component of the immunological synapse and serves as a key protein in the integrated T-cell antigen receptor (TCR)/CD28-induced signaling cascade leading to T-cell activation. However, the involvement o
Publikováno v:
Immunologic Research. 28:79-92
The Crk adapter proteins consist of Src homology 2 (SH2) SH2 and SH3 domains, which bind tyrosine-phosphorylated peptides and polyproline-rich motives, respectively. They are linked to multiple signaling pathways in different cell types, including ly
Publikováno v:
The Journal of Immunology. 165:1243-1251
TCR interaction with peptide-MHC complexes triggers migration of protein kinases, actin-binding proteins, and other accessory molecules to the T cell/APC synapse. We used confocal immunofluorescence methods to show that the adapter protein LAT (linke
Autor:
Maria Rosa Bani, Wendy Chu, Yaacov Ben-David, Robert S. Kerbel, Monika Kapoor, Ami Tamir, Brian J. Pak, Shi-Jiang Lu
Publikováno v:
Oncogene. 19:395-402
A major obstacle in the systemic treatment of advanced malignant melanoma is its intrinsic resistance to conventionally used chemotherapeutic agents. In order to investigate the mechanisms of this intrinsic resistance, we have previously utilized ret
Publikováno v:
Scopus-Elsevier
Commercial dialysate inhibits TNFα mRNA expression and NF-κB DNA-binding activity in LPS-stimulated macrophages. Continuous ambulatory peritoneal dialysis is known to interfere with the normal inflammatory responses of macrophages in the peritoneal