Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ami Ashar-Patel"'
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3057-3070 (2017)
The huntingtin gene has two mRNA isoforms that differ in their 3′ UTR length. The relationship of these isoforms with Huntington’s disease is not established. We provide evidence that the abundance of huntingtin 3′ UTR isoforms differs between
Externí odkaz:
https://doaj.org/article/90b65770c117485888e44cf808c52d55
Autor:
Augustine Rajakumar, Jeffrey A. Bailey, Yasin Kaymaz, S. Ananth Karumanchi, Ami Ashar-Patel, Melissa J. Moore
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Maternal symptoms of preeclampsia (PE) are primarily driven by excess anti-angiogenic factors originating from the placenta. Chief among these are soluble Flt1 proteins (sFlt1s) produced from alternatively polyadenylated mRNA isoforms. Here we used p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6032473f4761974168076a877c486a0
http://link.springer.com/article/10.1038/s41598-017-11639-6
http://link.springer.com/article/10.1038/s41598-017-11639-6
Autor:
Renuka Shanmugalingam, Anton A. Turanov, Melissa J. Moore, Reka A. Haraszti, Suzanne Pears, Dimas Echeverria, Julia F. Alterman, S. Ananth Karumanchi, Andrew H. Coles, Jim Iliopoulos, Anastasia Khvorova, Loic Roux, Robert Ogle, Zsuzsanna K. Zsengellér, Bruno M.D.C. Godinho, Matthew R. Hassler, Ami Ashar-Patel, Angela Makris, Agnes Lo, Annemarie Hennessy
Publikováno v:
Nature biotechnology
Preeclampsia is a placentally induced hypertensive disorder of pregnancy that is associated with substantial morbidity and mortality to mothers and fetuses. Clinical manifestations of preterm preeclampsia result from excess circulating soluble vascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fa6deb93edfbc8a9b72a20c603d997
http://europepmc.org/articles/PMC6526074
http://europepmc.org/articles/PMC6526074
Autor:
Nicholas Rhind, Melissa J. Moore, Jing Yan, Hennady P. Shulha, Weijun Chen, Ami Ashar-Patel, Zhiping Weng, Karin M. Green, Charles C. Query
Publikováno v:
RNA. 20:308-320
Excision of introns from pre-mRNAs is mediated by the spliceosome, a multi-megadalton complex consisting of U1, U2, U4/U6, and U5 snRNPs plus scores of associated proteins. Spliceosome assembly and disassembly are highly dynamic processes involving m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ac1990d2704e4b61e6793ad0eb5466
https://doi.org/10.1261/rna.040980.113
https://doi.org/10.1261/rna.040980.113
Autor:
Erin E. Heyer, Melissa J. Moore, Can Cenik, Alper Kucukural, Emiliano P. Ricci, Lingtao Peng, Guramrit Singh, Blandine C. Mercier, Ami Ashar-Patel
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2014, 21 (1), pp.26-35. ⟨10.1038/nsmb.2739⟩
Nature Structural and Molecular Biology, 2014, 21 (1), pp.26-35. ⟨10.1038/nsmb.2739⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2014, 21 (1), pp.26-35. ⟨10.1038/nsmb.2739⟩
Nature Structural and Molecular Biology, 2014, 21 (1), pp.26-35. ⟨10.1038/nsmb.2739⟩
International audience; Human Staufen1 (Stau1) is a double-stranded RNA (dsRNA)-binding protein implicated in multiple post-transcriptional gene-regulatory processes. Here we combined RNA immunoprecipitation in tandem (RIPiT) with RNase footprinting,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719e727b313ab680417f176196a3f54a
https://hal.archives-ouvertes.fr/hal-02444503/document
https://hal.archives-ouvertes.fr/hal-02444503/document
