Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ami Albihn"'
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27988 (2011)
Expression of MYC is deregulated in a wide range of human cancers, and is often associated with aggressive disease and poorly differentiated tumor cells. Identification of compounds with selectivity for cells overexpressing MYC would hence be benefic
Externí odkaz:
https://doaj.org/article/557cb0d08aec44cb84192ed806e03532
Autor:
Lina Guerra, Ami Albihn, Susanna Tronnersjö, Qinzi Yan, Riccardo Guidi, Bo Stenerlöw, Torsten Sterzenbach, Christine Josenhans, James G Fox, David B Schauer, Monica Thelestam, Lars-Gunnar Larsson, Marie Henriksson, Teresa Frisan
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mitochondrial
Externí odkaz:
https://doaj.org/article/f9d1a61ae3ac4f2fb16236f8f4b576aa
Publikováno v:
International Journal of Cancer. 121:1821-1829
The MYC oncogene is frequently deregulated in human tumors, indicative of a poor prognosis because of enhanced resistance to treatment. In such cases, the cellular sensitivity to chemotherapy could be restored by reactivation of Myc-driven apoptosis.
Publikováno v:
Encyclopedia of Cancer ISBN: 9783642278419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5fe71e43ba374b8462af7278060e6c5
https://doi.org/10.1007/978-3-642-27841-9_3923-2
https://doi.org/10.1007/978-3-642-27841-9_3923-2
Autor:
Marie Henriksson, Maria Teresa Bejarano, Susanne Osterdahl Brijker, Ami Albihn, Charlotte Asker, Lyda M. Osorio, Tobias Cornvik
Publikováno v:
Experimental Cell Research. 260:61-72
Mad1 is a Myc antagonist that heterodimerizes with Max and functions as a transcriptional repressor. We have studied the effects of Mad1 on cell growth, cell cycle distribution, and apoptosis using Mad1-inducible cell lines. Expression of Mad1 inhibi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 11, p e27988 (2011)
PLoS ONE, Vol 6, Iss 11, p e27988 (2011)
Expression of MYC is deregulated in a wide range of human cancers, and is often associated with aggressive disease and poorly differentiated tumor cells. Identification of compounds with selectivity for cells overexpressing MYC would hence be benefic
Publikováno v:
Advances in cancer research. 107
MYC proteins (c-MYC, MYCN, and MYCL) regulate processes involved in many if not all aspects of cell fate. Therefore, it is not surprising that the MYC genes are deregulated in several human neoplasias as a result from genetic and epigenetic alteratio
Autor:
Riccardo Guidi, Monica Thelestam, Ami Albihn, Lars-Gunnar Larsson, James G. Fox, Marie Henriksson, David B. Schauer, Lina Guerra, Torsten Sterzenbach, Teresa Frisan, Susanna Tronnersjö, Qinzi Yan, Bo Stenerlöw, Christine Josenhans
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
Background The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mit
MYC proteins (c-MYC, MYCN, and MYCL) regulate processes involved in many if not all aspects of cell fate. Therefore, it is not surprising that the MYC genes are deregulated in several human neoplasias as a result from genetic and epigenetic alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee8deac6813977ea55cd16cc49a3a059
https://doi.org/10.1016/s0065-230x(10)07006-5
https://doi.org/10.1016/s0065-230x(10)07006-5