Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amera O. Ibrahim"'
Autor:
Mariam Ali Abo-Saif, Amany E. Ragab, Amera O. Ibrahim, Othman F. Abdelzaher, Ahmed B. M. Mehanyd, Maha Saber-Ayad, Ola A. El-Feky
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Pyroptosis is an inflammatory programmed cell death accompanied by activation of inflammasomes and maturation of pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. Pyroptosis is closely linked to the development of diabetic ca
Externí odkaz:
https://doaj.org/article/24ec91116960407f912d6a8c8f89017f
Publikováno v:
Current Drug Safety. 17:250-258
Background: Anemia is one of the most common complications of Chronic Kidney Disease (CKD). The vast majority of Egyptian CKD patients are interchangeably treated with Darbepoetin Alfa (DPA) and Epoetin Alfa (EPA) to achieve and maintain target hemog
Autor:
Shaimaa M. Aboukhatwa, Amera O. Ibrahim, Hiroshi Aoyama, Ahmed S. Al-Behery, Moataz A. Shaldam, Ghada El-Ashmawy, Haytham O. Tawfik
Publikováno v:
Bioorganic chemistry. 129
Although a plethora of targeted anticancer small molecule drugs became available, the low response rate and drug resistance imply the continuous need for expanding the anticancer chemical space. In this study, a novel series of nicotinonitrile deriva
Publikováno v:
Biomedicine & Pharmacotherapy. 156:113971
Gentamycin-induced nephrotoxicity is related to stimulation of oxidative stress and inflammatory cascades leading to apoptotic renal damage. Heme oxygenase-1 (HO-1) induction considered to be an adaptive response against oxidative tissue damage. Our
Publikováno v:
Clinical and Translational Oncology. 22:1155-1165
Emerging evidence suggests that one of the main reasons of chemotherapy treatment failure is the development of multi-drug resistance (MDR) associated with cancer stem cells (CSCs). Our aim is to identify a therapeutic strategy based on MDR-reversing
Publikováno v:
Current drug safety. 17(3)
Anemia is one of the most common complications of Chronic Kidney Disease (CKD). The vast majority of Egyptian CKD patients are interchangeably treated with Darbepoetin Alfa (DPA) and Epoetin Alfa (EPA) to achieve and maintain target hemoglobin levels
Publikováno v:
Molecular immunology. 111
Background and aim Cancer stem cells (CSCs) are rare cell population present in the tumor bulk that are thought to be the reason for treatment failure following chemotherapy in terms of their intrinsic chemo-resistance. Our study aimed to develop an
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 42:979-987
Summary Hepatic fibrosis is an outcome of chronic liver injury. Angiotensin II (ANG II) may play a role in the pathogenesis of hepatic fibrosis. Certain drugs such as ACE inhibitors, ANG II antagonists, and even statins could interfere with the renin