Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Amera K. Remick"'
Autor:
Brian C. Gilger, Richard R. Dubielzig, Amera K. Remick, Mark Vezina, Martin Bussieres, Janet M. Petruska, Keith Robinson, Typhaine Lejeune
Publikováno v:
Toxicologic pathology. 47(4)
In a juvenile toxicology program, an unexpected finding of vacuolation of inner nuclear, ganglion cell, and nerve fiber layers of the retina was observed microscopically in routine Davidson’s fixed and hematoxylin and eosin–stained tissue section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d7fe2cd230708bbd4a25643c05146a
https://pubmed.ncbi.nlm.nih.gov/31064296
https://pubmed.ncbi.nlm.nih.gov/31064296
Autor:
Catherine A. Picut, Amera K. Remick
Publikováno v:
Toxicologic Pathology for Non-Pathologists ISBN: 9781493997763
To cover the broad topic of juvenile pathology, an overview of the regulatory landscape and explanation regarding when and why pathologists examine juvenile tissues in preclinical safety studies are provided. There are unique challenges and opportuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43fe2289370739344f83bff6da698fb2
https://doi.org/10.1007/978-1-4939-9777-0_19
https://doi.org/10.1007/978-1-4939-9777-0_19
Autor:
Claudine Tremblay, Lindsay Tomlinson, Vicki L. Sutherland, Karen S. Regan, Christopher J. Bowman, Michael Mirsky, Amera K. Remick, Midori Yoshida, Julian Oliver, Mehrdad Ameri, Kary E. Thompson, Wendy G. Halpern, Michael R. Elwell
Publikováno v:
Toxicologic Pathology. 44:789-809
Standard components of nonclinical toxicity testing for novel pharmaceuticals include clinical and anatomic pathology, as well as separate evaluation of effects on reproduction and development to inform clinical development and labeling. General stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b99f913c0b259c964a8a034a5be3376
https://doi.org/10.1177/0192623316650052
https://doi.org/10.1177/0192623316650052
Autor:
Alex K. Eapen, Andrey I. Nikiforov, Christine M. Crincoli, Marisa O. Rihner, Amera K. Remick, Witty A. Brathwaite
Publikováno v:
Food and Chemical Toxicology. 91:202-216
In a combined chronic toxicity/carcinogenicity study, groups of Crl:CD(SD) rats were fed 0 (2 control groups), 5000, 20,000, or 40,000 ppm (2R,4R)-monatin salt (hereafter "R,R-monatin") in the diet for up to one year in the chronic toxicity phase and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344d6615a8527d3977f6721730d59c4e
https://doi.org/10.1016/j.fct.2015.12.024
https://doi.org/10.1016/j.fct.2015.12.024
Autor:
Les Freshwater, Erin M. Quist, Amera K. Remick, James A. Swenberg, John M. Cullen, Robert R. Maronpot, Jerry F. Hardisty, Gary A. Boorman
Publikováno v:
Toxicologic pathology. 47(1)
A 24-month oral carcinogenicity study of permethrin was conducted by feeding male and female CD-1 mice diets containing concentrations of 0, 20, 500, and 2,000 ppm of permethrin (males) or 0, 20, 2,500, and 5,000 ppm of permethrin (females). After ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a42b351abcec7a5e01aef17343e20cb
https://pubmed.ncbi.nlm.nih.gov/30384807
https://pubmed.ncbi.nlm.nih.gov/30384807
Autor:
Roger Alison, Julia F.M. Baker, Lise Bertrand, Pamela E. Blackshear, Brad Blankenship, Gary Boorman, Suzanne Botts, Michael Boyle, Alys Bradley, Danielle L. Brown, Mark F. Cesta, Vivian Chen, Phaedra Cole, Michelle C. Cora, Darlene Dixon, Dale G. Dunn, Johnnie J. Eighmy, Susan A. Elmore, Michael R. Elwell, Scot L. Eustis, Pierluigi Fant, Stacey L. Fossey, John R. Foster, Denzil Frost, Silvia Guionaud, D. Greg Hall, Gordon C. Hard, Adam Hargreaves, Ronald A. Herbert, Kyathanahalli S. Janardhan, Michael P. Jokinen, Ken Latimer, Joel R. Leininger, Régis Masson, Jenny McKay, Mark G. Mense, Rodney A. Miller, Shunji Nakatsuji, Arun R. Pandiri, Nicola Parry, Deepa B. Rao, Marlon C. Rebelatto, Amera K. Remick, Thomas J. Rosol, Aude Roulois, Melissa Schutten, John Curtis Seely, Alok K. Sharma, Steven D. Sorden, Catherine Sutcliffe, Andrew W. Suttie, Kathleen A. Szabo, Gregory S. Travlos, Takeki Uehara, John L. Vahle, Justin D. Vidal, Katharine M. Whitney, Jyoji Yamate, Katsuhiko Yoshitomi, Katsuhiko Yoshizawa, Bevin Zimmerman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fbc2cbcd3b2d821621dbb8fdbd177b3
https://doi.org/10.1016/b978-0-12-391448-4.00043-5
https://doi.org/10.1016/b978-0-12-391448-4.00043-5
Publikováno v:
Toxicologic Pathology. 43:1166-1171
The Society of Toxicologic Pathology (STP) Education Committee and the STP Reproductive Special Interest Group held a North Carolina regional meeting entitled, “Juvenile Toxicology: Relevance and Challenges for Toxicologists and Pathologists” on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4157051216be24cd5905704a0ce32b86
https://doi.org/10.1177/0192623315595883
https://doi.org/10.1177/0192623315595883
Publikováno v:
International journal of toxicology. 36(4)
In support of a clinical trial in the pediatric population, available nonclinical and clinical data provide input on the study design and safety monitoring considerations. When the existing data are lacking to support the safety of the planned pediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d62ffd1ac4291ca0d42f912d2a188e
https://pubmed.ncbi.nlm.nih.gov/28466670
https://pubmed.ncbi.nlm.nih.gov/28466670
Autor:
Michelle L. Pershing, Melissa J. Beck, Jonathan D. Toot, Amera K. Remick, Lisa G. Lanigan, Tracey L. Papenfuss
Publikováno v:
Immunopathology in Toxicology and Drug Development ISBN: 9783319473840
The central and peripheral components of the nervous system exhibit extensive integration and interaction with the immune system in both health and disease. Components of the adaptive immune system touch all systems in the body through the blood and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20252793e8421bb2fa89314b0a7cfd5f
https://doi.org/10.1007/978-3-319-47385-7_5
https://doi.org/10.1007/978-3-319-47385-7_5