Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in nutmeg-based plant food supplements

Autor: Sebastiaan Wesseling, Abdalmajeed M. Alajlouni, Jia Ning, Amer J. Al-Malahmeh, Jacques Vervoort, Ivonne M.C.M. Rietjens

Publikováno v: Journal of Applied Toxicology. 37:1254-1264

A risk assessment of nutmeg-based plant food supplements (PFS) containing different alkenylbenzenes was performed based on the alkenylbenzene levels quantified in a series of PFS collected via the online market. The estimated daily intake (EDI) of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87ab234b63722f84a84f84b4fec8db6b
https://doi.org/10.1002/jat.3491

Level of Alkenylbenzenes in Parsley and Dill Based Teas and Associated Risk Assessment Using the Margin of Exposure Approach

Autor: Amer J. Al-Malahmeh, Abdalmajeed M. Alajlouni, Ivonne M.C.M. Rietjens, Sebastiaan Wesseling, Farida Nur Isnaeni, Jacques Vervoort

Publikováno v: Journal of Agricultural and Food Chemistry, 64(45), 8640-8646
Journal of Agricultural and Food Chemistry 64 (2016) 45

Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8feae5a97e7ed355ac1380e1fbc7671f
https://doi.org/10.1021/acs.jafc.6b03650

Risk assessment of combined exposure to alkenylbenzenes through consumption of plant food supplements containing parsley and dill

Autor: Ivonne M.C.M. Rietjens, Jacques Vervoort, Marina Kalli, Amer J. Al-Malahmeh, Abdalmajeed M. Alajlouni, Sebastiaan Wesseling

Publikováno v: Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment 34 (2017) 12
Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment, 34(12), 2201-2211

A risk assessment was performed of parsley- and dill-based plant food supplements (PFS) containing apiol and related alkenylbenzenes. First, the levels of the alkenylbenzenes in the PFS and the resulting estimated daily intake (EDI) resulting from us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f84385db2d79f16f32a944c71e887e
https://research.wur.nl/en/publications/risk-assessment-of-combined-exposure-to-alkenylbenzenes-through-c

Mode of action based risk assessment of the botanical food-borne alkenylbenzene apiol from parsley using physiologically based kinetic (PBK) modelling and read-across from safrole

Autor: Reiko Kiwamoto, Amer J. Al_Malahmeh, Jacques Vervoort, Sebastiaan Wesseling, Ivonne M.C.M. Rietjens, Abdalmajeed M. Alajlouni, Ala′ A.A. Al-Subeihi, Ans E. M. F. Soffers

Publikováno v: Food and Chemical Toxicology 89 (2016)
Food and Chemical Toxicology, 89, 138-150

The present study developed physiologically-based kinetic (PBK) models for the alkenylbenzene apiol in order to facilitate risk assessment based on read-across from the related alkenylbenzene safrole. Model predictions indicate that in rat liver the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dcb7e065021f8dcabbaa8c94e3d23a
https://research.wur.nl/en/publications/mode-of-action-based-risk-assessment-of-the-botanical-food-borne-