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pro vyhledávání: '"Amer Ghali"'
Autor:
Jill Bayliss, Carl Koschmann, Chris Jones, Mariarita Santi, Nada Jabado, Daniel R. Wahl, Pooja Panwalkar, Anand Shankar, Viveka Nand Yadav, Siva Kumar Natarajan, Alexander R. Judkins, Arul M. Chinnaiyan, Amer Ghali, Selin Jessa, Tingting Qin, Stefan Sweha, Chan Chung, Marcin Cieslik, Drew Pratt, Kari Wilder-Romans, Visweswaran Ravikumar, Daniel Martinez, Suzanne J. Baker, Sriram Venneti, Timothy N. Phoenix, Andrew J. Scott, Matthew Pun, Alan L. Mackay, Arvind Rao, Claudia L. Kleinman
Publikováno v:
Sci Transl Med
High-grade gliomas with arginine or valine substitutions of the histone H3.3 glycine-34 residue (H3.3G34R/V) carry a dismal prognosis, and current treatments, including radiotherapy and chemotherapy, are not curative. Because H3.3G34R/V mutations rep