Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Amer Abouhamze"'
Autor:
Stephen J. Pandol, Jo Ann Rinaudo, Darwin L. Conwell, Steven J. Hughes, Douglas S. Fishman, Mark E. Lowe, Hanno Steen, Robert Y. Liu, William E. Fisher, Amer Abouhamze, Amy L. McElhany, Ziding Feng, Zobeida Cruz-Monserrate, Gregory B. Lesinski, Sudhir Srivastava, Mark Topazian, David M. Troendle, Thomas A. Mace, Zachary M. Sellers, Ria Ghosh, Robert Orr, Dhiraj Yadav, Phil A. Hart, David C. Whitcomb, Jose Serrano, Aliye Uc, Emily Y. Lu, George Van Buren
Publikováno v:
Pancreas. 47(10)
High-quality and well-annotated biorepositories are needed to better understand the pathophysiology and biologic mechanisms of chronic pancreatitis (CP) and its consequences. We report a methodology for the development of a robust standard operating
Autor:
Cecelia Lopez, Alex G. Cuenca, Lori F. Gentile, Michael Armbruster, Ricardo Ungaro, Frederick A. Moore, Henry V. Baker, Amer Abouhamze, Philip A. Efron, Dina C. Nacionales, Darwin Ang
Publikováno v:
Critical Care Medicine. 41:1075-1085
OBJECTIVE To develop a novel polytrauma model that better recapitulates the immunologic response of the severely injured patient by combining long-bone fracture, muscle tissue damage, and cecectomy with hemorrhagic shock, resulting in an equivalent I
Autor:
Noel I. Ejaz, Bhagwan Dass, Amer Abouhamze, A. Ahsan Ejaz, Richard J. Johnson, Vijaykumar Lingegowda, Thomas M. Beaver, Michiko Shimada
Publikováno v:
International Urology and Nephrology. 45:449-458
Serum uric acid (SUA) is a novel risk factor for acute kidney injury (AKI), which adversely affects renal blood flow autoregulation, glomerular filtration rate (GFR), and promotes inflammation and angiogenesis. This pilot study investigated the effec
Autor:
Alex G. Cuenca, Ricardo Ungaro, Lyle L. Moldawer, Claudia Roberta de Castro Moreno, Larry Martin, Amer Abouhamze, Henry V. Baker, Ronald G. Tompkins, Kerri A. O’Malley, Kenneth T. Kotz, Kindra M. Kelly-Scumpia, Jennifer Lanz, M. Cecilia Lopez, Philip A. Efron, Elizabeth A. Warner, Mehmet Toner
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Gene expression analysis can be a powerful tool in predicting patient outcomes and identifying patients who may benefit from targeted therapies. However, isolating human blood polymorphonuclear cells (PMNs) for genomic analysis has been challenging.
Autor:
Henry V. Baker, Mashkoor A. Choudhry, Ronald W. Davis, Wenzhong Xiao, H. Shaw Warren, Mehmet Toner, John A. Mannick, J. Perren Cobb, Cynthia L. Tannahill, Celeste C. Finnerty, David N. Herndon, Matthew B. Klein, Michael B. Shapiro, Iris Garcia, Daniel Irimia, George Casella, Stephen F. Lowry, Philip H. Mason, Richard L. Gamelli, Aman Russom, David G. Camp, Grant E. O'Keefe, Nicole S. Gibran, Martin G. Schwacha, Timothy R. Billiar, Douglas Hayden, Palaniappan Sethu, Amer Abouhamze, Constance Elson, Paul E. Bankey, Brian G. Harbrecht, Avery B. Nathens, William J. Hubbard, Julie Wilhelmy, Asit De, Ernest E. Moore, John D. Storey, Bradley D. Freeman, Michael N. Mindrinos, M. Cecilia Lopez, Bernard H. Brownstein, Daniel G. Remick, Tanya Logvinenko, Richard D. Smith, Bruce A. McKinley, Jureta W. Horton, Steve E. Calvano, Ronald V. Maier, Carol L. Miller-Graziano, David A. Schoenfeld, Joseph P. Minei, Grace P. McDonald-Smith, Frederick A. Moore, Michael West, Ronald G. Tompkins, Laurence G. Rahme, Irshad H. Chaudry, Jeffrey A. Johnson, Lyle L. Moldawer, James A. Lederer, Geoffrey M. Silver
Publikováno v:
Clinical Chemistry. 54:891-900
Background: Microarray technology is becoming a powerful tool for diagnostic, therapeutic, and prognostic applications. There is at present no consensus regarding the optimal technique to isolate nucleic acids from blood leukocyte populations for sub
Autor:
Beth Hutchins, Amer Abouhamze, Philip A. Efron, Michelle Murday, Ricardo Ungaro, Priscilla F. McAuliffe, Philip O. Scumpia, Lyle L. Moldawer, Cynthia L. Tannahill, Drake LaFace
Publikováno v:
Gene Therapy. 13:276-282
Targeted expression of interleukin-10 (IL-10) has been proposed as a means to suppress acute and chronic inflammation. We explored the capacity of targeted adenoviral expression of human or viral IL-10 to improve outcome in a zymosan-induced model of
Autor:
Kathleen H Groover, Philip M. Baird, Francine M. Benes, Chris Hia, Melissa Rawley-Payne, Rosie Kizza, Zdenka Prodanovic, Amer Abouhamze, Chun-Hung Chan, Chon Boon Eng
Publikováno v:
Biopreservation and biobanking. 11(4)
Recent years have seen a great many natural disasters-superstorms, droughts, earthquakes, among others-as well as, in the biobanking world, the constant threat of man-made disaster with everything from freezer malfunctions to theft. To help inform th
Autor:
Amer Abouhamze, Jill Gasser, Lyle L. Moldawer, J. Frazier, Tadahiko Kohno, Angela Nelson, Carl K. Edwards, Steven W. Martin, William J. Boyle, James Ervin Seely, Olaf B Kinstler, Gary L. Kieft, Jeff Rose, Jason J. Rosenberg, Kunitaro Fukuzuka, William Marshall, Gregory C. Gaines, Ulrich Feige, Judy St. Clair
Publikováno v:
Journal of Applied Physiology. 91:2213-2223
Pharmacokinetics and immunogenicity of six different recombinant human soluble p55 tumor necrosis factor (TNF) receptor I (sTNFR-I) constructs were evaluated in juvenile baboons. The constructs included either an sTNFR-I IgG1 immunoadhesin (p55 sTNFR
Autor:
Jason J. Rosenberg, Michael D Taylor, David Hirsh, Emmet Hirsch, Carmen C. Solorzano, Sally L. D. MacKay, Daniel Topping, Lyle L. Moldawer, Amer Abouhamze, Mark A. Labow, Michael D. Josephs
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 278:R824-R830
A complete understanding of the role for endogenously produced interleukin-1 (IL-1), tumor necrosis factor-α (TNF-α), and IL-1 receptor antagonist (IL-1ra) in the acute phase response to inflammation remains unknown. In the present studies, knockou
Autor:
Troy Auffenberg, Julie Baumhofer, Lyle L. Moldawer, Richard J. Howard, Amer Abouhamze, N J Espat
Publikováno v:
Annals of Surgery. 223:428-433
OBJECTIVE: The present study was designed to evaluate whether pre-existing hepatic dysfunction (cirrhosis) leads to increased morbidity and mortality, in part through an inappropriate in vivo tumor necrosis factor-alpha response. SUMMARY BACKGROUND D