Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver.

Autor: Amenya HZ; Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan., Tohyama C; Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.; Experimental Biology Laboratory, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan., Ohsako S; Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Publikováno v: Scientific reports [Sci Rep] 2016 Oct 07; Vol. 6, pp. 34989. Date of Electronic Publication: 2016 Oct 07.

Sub-acute toxicity of the chloroformic extract of Rapanea melanophloeos (L.) Mez in rats.

Autor: Amenya HZ; Department of Public Health, Pharmacology and Toxicology, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya., Gathumbi PK; Department of Veterinary Pathology, Microbiology and Parasitology, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya. Electronic address: gathumbi@uonbi.ac.ke., Mbaria JM; Department of Public Health, Pharmacology and Toxicology, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya., Thaiyah AG; Department of Clinical Studies, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya., Thoithi GN; School of Pharmacy, University of Nairobi, P.O. Box 19676-00202, Nairobi, Kenya.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2014 Jul 03; Vol. 154 (3), pp. 593-9. Date of Electronic Publication: 2014 Apr 13.