Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Amena Archer"'
Autor:
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker M Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 374-402 (2024)
Abstract Sex-based differences in obesity-related hepatic malignancies suggest the protective roles of estrogen. Using a preclinical model, we dissected estrogen receptor (ER) isoform-driven molecular responses in high-fat diet (HFD)-induced liver di
Externí odkaz:
https://doaj.org/article/ee239cfd60044f218b6abfe27eac0000
Autor:
Madeleine Birgersson, Rajitha Indukuri, Linnéa Lindquist, Lina Stepanauskaite, Qing Luo, Qiaolin Deng, Amena Archer, Cecilia Williams
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and ovulation, yet its exact mechanism of action is mainly uncharacterized. Results We here performed ERβ ChIP-sequencing of mouse ovaries followed by c
Externí odkaz:
https://doaj.org/article/727a9789e99f4472ba2342400bbc6e90
Autor:
Linnea Hases, Lina Stepanauskaite, Madeleine Birgersson, Nele Brusselaers, Ina Schuppe-Koistinen, Amena Archer, Lars Engstrand, Cecilia Williams
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
A metagenomic analysis reveals that male and female mice exhibit sex-dependent responses to a high-fat diet (HFD), and that estrogenic ligands can attenuate certain aspects of HFDinduced dysbiosis.
Externí odkaz:
https://doaj.org/article/3a1403a1393f4fdbaf958e75f5ebbdec
Autor:
Marcela González-Granillo, Luisa A. Helguero, Eliana Alves, Amena Archer, Christina Savva, Matteo Pedrelli, Osman Ahmed, Xidan Li, Maria Rosário Domingues, Paolo Parini, Jan-Åke Gustafsson, Marion Korach-André
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract The response to overfeeding is sex dependent, and metabolic syndrome is more likely associated to obesity in men or postmenopausal women than in young fertile women. We hypothesized that obesity-induced metabolic syndrome is sex dependent du
Externí odkaz:
https://doaj.org/article/5766bece7b7e48c0b13564399c068757
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Inflammation is a primary component of both initiation and promotion of colorectal cancer (CRC). Cytokines secreted by macrophages, including tumor necrosis factor alpha (TNFα), activates the pro-survival transcription factor complex NFκB. The prec
Externí odkaz:
https://doaj.org/article/f6d5919d601c402bb804aa80e389c609
Autor:
Madeleine Birgersson, Rajitha Indukuri, Per Antonson, Ivan Nalvarte, Amena Archer, Cecilia Williams
Publikováno v:
Endocrinology. 164
Granulosa cell tumors (GCTs) are rare ovarian tumors comprising an adult and a juvenile subtype. They have a generally good prognosis, but the survival rate drastically declines in patients with late-stage or recurring tumors. Due to the rarity of GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c9d748ccc6db13c9675ff57a52bcc7
https://doi.org/10.1210/endocr/bqad063
https://doi.org/10.1210/endocr/bqad063
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10408
There are significant sex differences in colorectal cancer (CRC), including in incidence, onset, and molecular characteristics. Further, while inflammatory bowel disease (IBD) is a risk factor for CRC in both sexes, men with IBD have a 60% higher ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c22eb0a95d4c6bc2f6bf2e7aee8c3f
Autor:
Mariel Perez-Zabaleta, Amena Archer, Kasra Khatami, Mohammed Hakim Jafferali, Prachi Nandy, Merve Atasoy, Madeleine Birgersson, Cecilia Williams, Zeynep Cetecioglu
Publikováno v:
The Science of the total environment. 858(Pt 3)
Wastewater-based epidemiology (WBE) can be used to track the spread of SARS-CoV-2 in a population. This study presents the learning outcomes from over two-year long monitoring of SARS-CoV-2 in Stockholm, Sweden. The three main wastewater treatment pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c8497a6d0254e353c03d3793a15e2a
https://pubmed.ncbi.nlm.nih.gov/36356735
https://pubmed.ncbi.nlm.nih.gov/36356735
Autor:
Huan He, Cecilia Williams, Dandan Song, Lars Arne Haldosén, Feifei Yan, Amena Archer, Indranil Sinha, Chunyan Zhao, Linnea Hases
Publikováno v:
Cancer Letters. 506:23-34
The AP-1 member Fra-1 is overexpressed in TNBC and plays crucial roles in tumor progression and treatment resistance. In a previous large-scale screen, we identified PARP1 to be among 118 proteins that interact with endogenous chromatin-bound Fra-1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c99325431306d84bc4d301b5566fcb
https://doi.org/10.1016/j.canlet.2021.02.018
https://doi.org/10.1016/j.canlet.2021.02.018
Autor:
Amena Archer, Émilie Stolarczyk, Maria Luisa Doria, Luisa Helguero, Rosário Domingues, Jane K. Howard, Agneta Mode, Marion Korach-André, Jan-Åke Gustafsson
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 5, Pp 1300-1311 (2013)
To investigate the role of liver X receptor (LXR) in adipose tissue metabolism during obesity, ob/ob mice were treated for 5 weeks with the synthetic LXR agonist GW3965. MRI analysis revealed that pharmacological activation of LXR modified fat distri
Externí odkaz:
https://doaj.org/article/027985524ccf408697705e3b70a0de82