Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amelita A. Calejesan"'
Publikováno v:
Molecular Pain, Vol 1, Iss 1, p 6 (2005)
Molecular Pain
Molecular Pain
Identifying higher brain central region(s) that are responsible for the unpleasantness of pain is the focus of many recent studies. Here we show that direct stimulation of the anterior cingulate cortex (ACC) in mice produced fear-like freezing respon
Publikováno v:
Pharmacology Biochemistry and Behavior. 73:429-437
In this study, we provide evidence that focal electrical stimulation applied to the rostroventral medulla (RVM) at a high frequency (100 Hz) produced inhibition of the spinal nociceptive tail-flick (TF) reflex in lightly anesthetized adult rats. Chem
Publikováno v:
The Journal of Pain. 3:292-300
Activity-dependent synaptic plasticity occurs in many regions of the central nervous system. It is known that spinal sensory transmission undergoes long-lasting changes after tissue injury and inflammation, but much less is known about descending mod
Publikováno v:
European Journal of Pain. 4:83-96
It is well documented that the descending endogenous analgesia system, including the periaqueductal gray (PAG) and the rostral ventral medulla (RVM), play an important role in modulation of nociceptive transmission and morphine- and cannabinoid-produ
Publikováno v:
Brain Research. 829:185-189
We investigated sex- or gender-dependent differences in nociception using the formalin test in mice. In addition to typical biphasic responses, a new, late phase (Phase 3) was observed. A local anesthetic QX-314 injected at the end of Phase 2 blocked
Publikováno v:
Journal of Neurophysiology. 80:3356-3360
Li, Ping, Amelita A. Calean, and Min Zhuo. ATP P2× receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats. J. Neurophysiol. 80: 3356–3360, 1998. Glutamate is a major fast transmitter betw
Publikováno v:
Current neurovascular research. 1(1)
It is well documented that sensory transmission, including pain, is subject to endogenous inhibitory modulatory influences at dorsal horn of the spinal cord. Recent results, from behavioral to molecular studies, demonstrate that endogenous modulatory
Publikováno v:
Nature. 397(6715)
Glutamate, the major excitatory neurotransmitter in the central nervous system, activates three different receptors that directly gate ion channels, namely receptors for AMPA (alpha-amino-3-hydroxy-5-methyl isoxozole propionic acid), NMDA (N-methyl-D
Publikováno v:
Brain research. 798(1-2)
It is documented that spinal nociceptive transmission receives descending facilitatory and inhibitory modulation from supraspinal structures. The rostral ventral medulla (RVM), including the nucleus raphe magnus (NRM), nuclei reticularis gigantocellu