Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amelie Schreieck"'
Autor:
Kim M. Stegmann, Antje Dickmanns, Natalie Heinen, Claudia Blaurock, Tim Karrasch, Angele Breithaupt, Robert Klopfleisch, Nadja Uhlig, Valentina Eberlein, Leila Issmail, Simon T. Herrmann, Amelie Schreieck, Evelyn Peelen, Hella Kohlhof, Balal Sadeghi, Alexander Riek, John R. Speakman, Uwe Groß, Dirk Görlich, Daniel Vitt, Thorsten Müller, Thomas Grunwald, Stephanie Pfaender, Anne Balkema-Buschmann, Matthias Dobbelstein
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104293- (2022)
Summary: The nucleoside analog N4-hydroxycytidine (NHC) is the active metabolite of the prodrug molnupiravir, which has been approved for the treatment of COVID-19. SARS-CoV-2 incorporates NHC into its RNA, resulting in defective virus genomes. Likew
Externí odkaz:
https://doaj.org/article/3893fdc86a5b4569a07925c5deb2bfb2
Autor:
Kristin Leike, Andreas Mayer, Patrick Cramer, Amelie Schreieck, Michael Lidschreiber, Dietmar E. Martin
Publikováno v:
Molecular and Cellular Biology
During transcription elongation, RNA polymerase II (Pol II) binds the general elongation factor Spt5. Spt5 contains a repetitive C-terminal region (CTR) that is required for cotranscriptional recruitment of the Paf1 complex (D. L. Lindstrom et al., M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e7073a388a2a34d796ae894a70c036
https://doi.org/10.1128/mcb.06310-11
https://doi.org/10.1128/mcb.06310-11
Autor:
Sebastian R. Geiger, Kristina Lorenzen, Dirk Kostrewa, Patrick Cramer, Amelie Schreieck, Albert J. R. Heck, Patrizia Hanecker
Publikováno v:
Molecular Cell
The eukaryotic RNA polymerases Pol I, II, and III use different promoters to transcribe different classes of genes. Promoter usage relies on initiation factors, including TFIIF and TFIIE, in the case of Pol II. Here, we show that the Pol I-specific s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5654a8dd8b079bf17353fb7fb6e6741
https://doi.org/10.1016/j.molcel.2010.07.028
https://doi.org/10.1016/j.molcel.2010.07.028
Autor:
Dirk Eick, Axel Imhof, Tim-Michael Decker, Roland Schüller, Patrick Cramer, Amelie Schreieck, Nilay Shah, Ignasi Forné, Tobias Straub, Yves Texier
Publikováno v:
Molecular Cell
Mol. Cell 61, 305-314 (2016)
Mol. Cell 61, 305-314 (2016)
The carboxy-terminal domain (CTD) of RNA polymerase II (Pol II) consists of heptad repeats with the consensus motif Y1-S2-P3-T4-S5-P6-S7. Dynamic phosphorylation of the CTD coordinates Pol II progression through the transcription cycle. Here, we use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcf5fdeb1336009433d20dc88ce7a51
https://hdl.handle.net/11858/00-001M-0000-0029-69F7-911858/00-001M-0000-0029-69F5-D11858/00-001M-0000-0029-69F6-B11858/00-001M-0000-0029-69F1-6
https://hdl.handle.net/11858/00-001M-0000-0029-69F7-911858/00-001M-0000-0029-69F5-D11858/00-001M-0000-0029-69F6-B11858/00-001M-0000-0029-69F1-6
Autor:
Michael Lidschreiber, Corinna Hintermair, Martin Heidemann, Mai Sun, Patrick Cramer, Elisabeth Kremmer, Amelie Schreieck, Dirk Eick, Andreas Mayer
Publikováno v:
Science
Don't Terminate Me! DNA transcription progresses through three phases—initiation, elongation, and termination—of messenger RNA chains. The transcribing enzyme, RNA polymerase (Pol) II, recruits factors that assist in each of these phases. Mayer e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde7dfb486b4756c3b11ced2e96ea4be
https://doi.org/10.1126/science.1219651
https://doi.org/10.1126/science.1219651
Autor:
Ashley D. Easter, Patrick Cramer, Lori A. Passmore, Amelie Schreieck, Katrin Wiederhold, Stefanie Etzold, Michael Lidschreiber
Publikováno v:
Nature Structural and Molecular Biology
At the 3' ends of protein-coding genes, RNA polymerase (Pol) II is dephosphorylated at tyrosine residues (Tyr1) of its C-terminal domain (CTD). In addition, the associated cleavage-and-polyadenylation factor (CPF) cleaves the transcript and adds a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9524387cab3a9e8ccca18802176947d
Autor:
Bart Claes, Alexander Kohlmann, Helen Brown, Benjamin S.G. Kong, Alessandro Rettino, Amelie Schreieck, R. Chaston, Anders Olof Herman Nygren, James Sherwood, Paul Choppa, Bhuwnesh Agrawal, Graeme R. Clark, Ina L. Deras
Publikováno v:
ESMO Open
Click here and here to see the linked articles Introduction This study assessed KRAS mutation detection and functional characteristics across 13 distinct technologies and assays available in clinical practice, in a blinded manner. Methods Five distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c8990bfbf3c23e9a6b47df4c8bb16b
https://doi.org/10.1136/esmoopen-2017-000235
https://doi.org/10.1136/esmoopen-2017-000235