Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Amelie Lupp"'
Autor:
Lorena Gerlach, Anna-Sophia Liselott Beyer, Daniel Kaemmerer, Jörg Sänger, Katja Evert, Stefan Schulz, Amelie Lupp
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Little is known about the expression of the orphan G protein-coupled receptor GPR19 at the protein level. Therefore, we developed a rabbit antibody, targeting human GPR19. After verification of the antibody specificity using GPR19-expressing
Externí odkaz:
https://doaj.org/article/f9b5f668eb56437aab61d7111a16c602
Autor:
Mor Oron-Herman, David Kirmayer, Amelie Lupp, Stefan Schulz, Genady Kostenich, Michel Afargan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Somatostatin receptors are clinically validated GPCR biomarkers for diagnosis and treatment of various neuroendocrine tumors (NET). Among the five somatostatin receptors, SST2 and SST3 are associated with apoptosis and cell cycle arrest, mak
Externí odkaz:
https://doaj.org/article/c0f0d22b062e45908917da22f1d691b0
Autor:
Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch, Uta Dahmen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Little is known about the impact of morphological disorders in distinct zones on metabolic zonation. It was described recently that periportal fibrosis did affect the expression of CYP proteins, a set of pericentrally located drug-metabolizi
Externí odkaz:
https://doaj.org/article/ab94040416be4b768ec4f1e797e54e72
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Somatostatin receptors SST1, SST2, and SST5 are overexpressed in neuroendocrine neoplasms (NENs), but little is known about SST4 expression in NENs because of a lack of specific monoclonal antibodies. We recently developed and thoroughly cha
Externí odkaz:
https://doaj.org/article/b944b8685f334282b0fb56eeb7723dbf
Autor:
Max Czajkowski, Daniel Kaemmerer, Jörg Sänger, Guido Sauter, Ralph M. Wirtz, Stefan Schulz, Amelie Lupp
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Papillary and follicular thyroid carcinomas can be treated surgically and with radioiodine therapy, whereas therapeutic options for advanced stage IV medullary and for anaplastic tumours are limited. Recently, somatostatin recepto
Externí odkaz:
https://doaj.org/article/15fd543455ee437ab243a9784f23f973
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101526- (2022)
Background: Targeting programmed death protein 1 (PD-1) or its ligand PD-L1 is a promising therapeutic approach for many types of cancer in which PD-L1 is overexpressed. However, data on PD-L1 expression levels in gastroenteropancreatic neuroendocrin
Externí odkaz:
https://doaj.org/article/55c4b80c319544af96ed6530a081d8e9
Publikováno v:
Endocrine Connections, Vol 10, Iss 2, Pp 180-190 (2021)
Programmed death protein 1 (PD-1) and its ligand, PD-L1, have emerged as promising therapeutic targets for many types of cancer that overexpress PD-L1. However, data on PD-L1 expression levels in bronchopulmonary neuroendocrine neoplasms (BP-NEN) are
Externí odkaz:
https://doaj.org/article/882393928b6141ac8410415d372677e0
Autor:
Benjamin Wende, Anna-Sophia Liselott Beyer, Niklas Ruhnke, Daniel Kaemmerer, Jörg Sänger, Stefan Schulz, Amelie Lupp
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3960 (2023)
Little information is available concerning protein expression of the calcitonin receptor-like receptor (CALCRL) at the protein level. Here, we developed a rabbit monoclonal antibody, 8H9L8, which is directed against human CALCRL but cross-reacts with
Externí odkaz:
https://doaj.org/article/b5cae405a9cc4fa5b0a8bfe8a04a223e
Autor:
Christoph Werner, Amelie Lupp, Gabriele Mtuka-Pardon, Christof Kloos, Gunter Wolf, René Aschenbach, Anika Biermann, Martin Freesmeyer, Philipp Seifert
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-5 (2020)
Abstract Background Primary hyperparathyroidism is a rare condition of disease which can seldomly present as giant retrotrhyroideal cysts, complicating the localization of the adenoma to resect. Case presentation A 56-year old female presented with h
Externí odkaz:
https://doaj.org/article/2ac5a5deb8e3442198c648e2f390b277
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13503 (2022)
Little is known about the adaptor protein FAM159B. Recently, FAM159B was shown to be particularly expressed in neuroendocrine cells and tissues, such as pancreatic islets and neuroendocrine cells of the bronchopulmonary and gastrointestinal tracts, a
Externí odkaz:
https://doaj.org/article/d217454174434ec681614faa47f90dc0