Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Amelie LUSQUE"'
Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma
Autor:
Mark Sementsov, Leonie Ott, Julian Kött, Alexander Sartori, Amelie Lusque, Sarah Degenhardt, Bertille Segier, Isabel Heidrich, Beate Volkmer, Rüdiger Greinert, Peter Mohr, Ronald Simon, Julia-Christina Stadler, Darryl Irwin, Claudia Koch, Antje Andreas, Benjamin Deitert, Verena Thewes, Andreas Trumpp, Andreas Schneeweiss, Yassine Belloum, Sven Peine, Harriett Wikman, Sabine Riethdorf, Stefan W Schneider, Christoffer Gebhardt, Klaus Pantel, Laura Keller
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1560-1578 (2024)
Abstract Circulating tumor DNA (ctDNA) is the cornerstone of liquid biopsy diagnostics, revealing clinically relevant genomic aberrations from blood of cancer patients. Genomic analysis of single circulating tumor cells (CTCs) could provide additiona
Externí odkaz:
https://doaj.org/article/4b6305c88a944631907935568207306e
Autor:
Anouchka Modesto, Aurore Siegfried, Amelie Lusque, Sébastien Vergez, Jerome Sarini, Laurent Brouchet, Emmanuelle Uro-Coste, Pierre Graff-Cailleaud, Jean Pierre Delord
Publikováno v:
Current Oncology, Vol 28, Iss 3, Pp 1673-1680 (2021)
Introduction: Recent modifications in the epidemiology of oropharyngeal squamous cell carcinoma (OSCC) have led to the increase of Human papillomavirus (HPV) related metastatic head and neck cancer patients with high life expectancy even at advanced
Externí odkaz:
https://doaj.org/article/0d99dd2291af410b8a93534817fcaee5
Autor:
Julien N. Bianco, Valérie Bergoglio, Yea-Lih Lin, Marie-Jeanne Pillaire, Anne-Lyne Schmitz, Julia Gilhodes, Amelie Lusque, Julien Mazières, Magali Lacroix-Triki, Theodoros I. Roumeliotis, Jyoti Choudhary, Jérôme Moreaux, Jean-Sébastien Hoffmann, Hélène Tourrière, Philippe Pasero
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Oncogene-induced replication stress (RS) promotes cancer development. Here, the authors report that cancer cells adapt to oncogene-induced RS by overexpressing downstream components of ATR-CHK1 pathway, Claspin and Timeless, which have protective rol
Externí odkaz:
https://doaj.org/article/fdf314771754477295f673e54990011e
Autor:
Fabrice Andre, Thomas Filleron, Maud Kamal, Fernanda Mosele, Monica Arnedos, Florence Dalenc, Marie-Paule Sablin, Mario Campone, Hervé Bonnefoi, Claudia Lefeuvre-Plesse, William Jacot, Florence Coussy, Jean-Marc Ferrero, George Emile, Marie-Ange Mouret-Reynier, Jean-Christophe Thery, Nicolas Isambert, Alice Mege, Philippe Barthelemy, Benoit You, Nawale Hajjaji, Ludovic Lacroix, Etienne Rouleau, Alicia Tran-Dien, Sandrine Boyault, Valery Attignon, Pierre Gestraud, Nicolas Servant, Christophe Le Tourneau, Linda Larbi Cherif, Isabelle Soubeyran, Filippo Montemurro, Alain Morel, Amelie Lusque, Marta Jimenez, Alexandra Jacquet, Anthony Gonçalves, Thomas Bachelot, Ivan Bieche
Publikováno v:
Nature
Nature, 2022, 610 (7931), pp.343-348. ⟨10.1038/s41586-022-05068-3⟩
Nature, 2022, 610 (7931), pp.343-348. ⟨10.1038/s41586-022-05068-3⟩
Cancer progression is driven in part by genomic alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11b6e4a3a2c6123cb66ae86667e677e
https://doi.org/10.1038/s41586-022-05068-3
https://doi.org/10.1038/s41586-022-05068-3
Autor:
Fabrice Andre, Mosele Fernanda, Elise Deluche, Amelie LUSQUE, Loic Le-Bescond, Thomas Filleron, Yoann Pradat, Agnes Ducoulombier, Barbara Pistilli, Thomas Bachelot, Frederic Viret, Christelle LEVY, Nicolas Signolle, Alexia Alfaro, Diep Tran, Ingrid GARBERIS, Hugues Talbot, Stergios Christodoulidis, Maria Vakalopoulou, Nathalie Droin, Aurelie Stourm, Maki Kobayashi, Tomaya Kakegawa, Ludovic Lacroix, Patrick Saulnier, Bastien Job, Marc Deloger, Marta Jimenez, Vianney Baris, Pierre Laplante, Patricia Kannouche, Virginie Marty, Magali Lacroix-Triki, Veronique Dieras
Trastuzumab deruxtecan (T-DXd) is an anti-HER2 (human epidermal growth factor receptor 2) antibody-drug conjugate which has previously shown efficacy in patients with HER2-overexpressing and HER2-low metastatic breast cancer (mBC). However, the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3d6f86c9dd4bce91f1964b7ce3766a
https://doi.org/10.21203/rs.3.rs-2083650/v1
https://doi.org/10.21203/rs.3.rs-2083650/v1
Autor:
Thomas, Bachelot, Thomas, Filleron, Ivan, Bieche, Monica, Arnedos, Mario, Campone, Florence, Dalenc, Florence, Coussy, Marie-Paule, Sablin, Marc, Debled, Claudia, Lefeuvre-Plesse, Anthony, Goncalves, Marie-Ange Mouret, Reynier, William, Jacot, Benoit, You, Philippe, Barthelemy, Benjamin, Verret, Nicolas, Isambert, Xavier, Tchiknavorian, Christelle, Levy, Jean-Christophe, Thery, Tifenn, L'Haridon, Jean-Marc, Ferrero, Alice, Mege, Francesco, Del Piano, Etienne, Rouleau, Alicia, Tran-Dien, Julien, Adam, Amelie, Lusque, Marta, Jimenez, Alexandra, Jacquet, Ingrid, Garberis, Fabrice, Andre
Publikováno v:
Nature medicine. 27(2)
The impact of single-agent antibodies against programmed death-ligand 1 (PD-L1) as maintenance therapy is unknown in patients with metastatic breast cancer. The SAFIR02-BREAST IMMUNO substudy included patients with human epidermal growth factor recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9152d37568a554ded7d27177bdb9ce49
https://pubmed.ncbi.nlm.nih.gov/33462450
https://pubmed.ncbi.nlm.nih.gov/33462450
Autor:
Antoine Boden, Amélie Lusque, Sabrina Lodin, Marie Bourgouin, Valérie Mauries, Christelle Moreau, Amandine Fabre, Muriel Mounier, Muriel Poublanc, Nathalie Caunes-Hilary, Thomas Filleron
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Neuropathic pain is common in cancer survivorship and is one of the most distressing symptoms for patients previously treated for head and neck cancer. Persistent neuropathic pain, when it is ongoing and uncontrolled, has a detrim
Externí odkaz:
https://doaj.org/article/f97ee87e071049daab092a21ae06f6c7
Autor:
Fernanda Mosele, Benjamin Verret, Amelie Lusque, Thomas Filleron, Thomas Bachelot, Monica Arnedos, Mario Campone, Florence Dalenc, Claudia Lefeuvre, Marie Paule Sablin, Hervé Bonnefoi, Ludovic Lacroix, Ivan Bièche, Anthony Gonçalves, William Jacot, Marta Jimenez, Amelie Jacquet, Fabrice Andre
Publikováno v:
Cancer Research. 79:4895-4895
BACKGROUND: Activating PIK3CA mutations occur in 20-30% of patients with metastatic breast cancer (mBC). A recent study showed that alpha selective PI3K inhibitors improve outcome in patients with PIK3CA mutation, HR+/Her2- mBC. There is a need to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3c344d81161ac7890f5ffe8f5faf542
https://doi.org/10.1158/1538-7445.am2019-4895
https://doi.org/10.1158/1538-7445.am2019-4895
Autor:
Corentin Pasquier, Léonor Chaltiel, Carole Massabeau, Audrey Rabeau, Louisiane Lebas, Amélie Lusque, Jean-Sébastien Texier, Elizabeth Cohen-Jonathan Moyal, Julien Mazières, Jonathan Khalifa
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe optimal modalities of radiotherapy when combining concurrent chemoradiation (CCRT) and immunotherapy (IO) for locally advanced non-small cell lung cancer (LA-NSCLC) remain to be determined. The aim of this study was to investigate the i
Externí odkaz:
https://doaj.org/article/3c6a0199c57e4c06acd097edb0d61c0c
Autor:
Alejandra Martinez, Elodie Chantalat, Martina Aida Angeles, Gwénaël Ferron, Anne Ducassou, Manon Daix, Justine Attal, Sarah Bétrian, Amélie Lusque, Erwan Gabiache
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background To assess the impact of PET/CT functional parameters on survival, locoregional, and distant failure according to the most distant level of lymph node [18F]FDG uptake in patients with locally advanced cervical cancer (LACC). Method
Externí odkaz:
https://doaj.org/article/eea699c005ea46bc9ba5628b24eecb06