Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amelie Fiene"'
Autor:
Younis Baqi, Mahmoud Rashed, Laura Schäkel, Enas M. Malik, Julie Pelletier, Jean Sévigny, Amelie Fiene, Christa E. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Ectonucleoside triphosphate diphosphohydrolases (NTPDases) catalyze the hydrolysis of nucleoside tri- and di-phosphates to mono-phosphates. The products are subsequently hydrolyzed by ecto-5′-nucleotidase (ecto-5′-NT) to nucleosides. NTPDase inhi
Externí odkaz:
https://doaj.org/article/e7d069e48d514c518acb6445ea293fe9
Autor:
Christa E. Müller, Andrea Behrenswerth, Katarzyna Kieć-Kononowicz, Meryem Köse, Sabrina Gollos, Fabian Heisig, Vigneshwaran Namasivayam, Tadeusz Karcz, Amelie Fiene
Publikováno v:
Journal of Medicinal Chemistry. 61:4301-4316
Fluorescent ligands represent powerful tools for biological studies and are considered attractive alternatives to radioligands. In this study, we developed fluorescent antagonists for A2B adenosine receptors (A2BARs), which are targeted by antiasthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d4c2c94ca8a0a1c7ff89ed20b2ec56
https://doi.org/10.1021/acs.jmedchem.7b01627
https://doi.org/10.1021/acs.jmedchem.7b01627
Autor:
Christa E. Müller, Wenjin Li, Sang Yong Lee, Patrice Newton, Enas M. Malik, Younis Baqi, Amelie Fiene, Elizabeth L. Hartland
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:4363-4371
Legionella pneumophila is an aerobic, Gram-negative bacterium of the genus Legionella, which constitutes the major causative agent of Legionnaires' disease. Recently a nucleoside triphosphate diphosphohydrolase (NTPDase) from L. pneumophila was ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9ddd92466f90bf6415d7476434ccb0
https://doi.org/10.1016/j.bmc.2016.07.027
https://doi.org/10.1016/j.bmc.2016.07.027
Autor:
Meryem, Köse, Sabrina, Gollos, Tadeusz, Karcz, Amelie, Fiene, Fabian, Heisig, Andrea, Behrenswerth, Katarzyna, Kieć-Kononowicz, Vigneshwaran, Namasivayam, Christa E, Müller
Publikováno v:
Journal of medicinal chemistry. 61(10)
Fluorescent ligands represent powerful tools for biological studies and are considered attractive alternatives to radioligands. In this study, we developed fluorescent antagonists for A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbee19ae03b715d3bc6f0938a92aba23
https://pubmed.ncbi.nlm.nih.gov/29681156
https://pubmed.ncbi.nlm.nih.gov/29681156
Publikováno v:
The Analyst. 140:140-148
The following members of the ecto-nucleoside triphosphate diphosphohydrolase family, NTPDase1 (CD39), NTPDase-2, -3, and -8, play an important role in purinergic signal transduction by regulating extracellular nucleotide levels. Potent and selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6035cafb08561a64a7372d2825fa59
https://doi.org/10.1039/c4an01694g
https://doi.org/10.1039/c4an01694g
Autor:
Ali El-Tayeb, Amelie Fiene, Herbert Zimmermann, Christa E. Müller, Aliaa Abdelrahman, Norbert Sträter, Anne Meyer, Sang-Yong Lee, Marianne Freundlieb, Jan Pippel, Sanjay Bhattarai, Gennady G. Yegutkin
Publikováno v:
Journal of Medicinal Chemistry. 58(15):6248-6263
ecto-5'-Nucleotidase (eN, CD73) catalyzes the hydrolysis of extracellular AMP to adenosine. eN inhibitors have potential for use as cancer therapeutics. The eN inhibitor α,β-methylene-ADP (AOPCP, adenosine-5'-O-[(phosphonomethyl)phosphonic acid]) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f79ee78fd3a9da47b0c865ad13ad1e4
http://juuli.fi/Record/0006750315
http://juuli.fi/Record/0006750315
Autor:
Sang-Yong Lee, Jan Pippel, Gennady G. Yegutkin, Christa E. Müller, Marianne Freundlieb, Sanjay Bhattarai, Aliaa Abdelrahman, Constanze C. Schmies, Norbert Sträter, Amelie Fiene, Ali El-Tayeb, Herbert Zimmermann, Anne Meyer
Publikováno v:
Advanced Therapeutics. 2:1900075
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e665e1b1bed7325ee4f7cfb424bd8ec
https://doi.org/10.1002/adtp.201900075
https://doi.org/10.1002/adtp.201900075
Autor:
Vladimir E. Fedorov, Joanna Lecka, Theodor Hanck, Sang-Yong Lee, Hans-Jürgen Pietzsch, Holger Stephan, Christa E. Müller, Konstantin A. Brylev, Ali Haider, Wenjin Li, Jean Sévigny, Herbert Zimmermann, Ulrich Kortz, Amelie Fiene
Publikováno v:
Biochemical pharmacology. 93(2)
Polyoxometalates (POMs) are inorganic cluster metal complexes that possess versatile biological activities, including antibacterial, anticancer, antidiabetic, and antiviral effects. Their mechanisms of action at the molecular level are largely unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c927c5560845492e4a8b4769ef9f4f
https://pubmed.ncbi.nlm.nih.gov/25449596
https://pubmed.ncbi.nlm.nih.gov/25449596
Autor:
Sanjay Bhattarai, Marianne Freundlieb, Jan Pippel, Anne Meyer, Aliaa Abdelrahman, Amelie Fiene, Sang-Yong Lee, Herbert Zimmermann, Gennady G. Yegutkin, Norbert Sträter, Ali El-Tayeb, Christa E. Müller
Publikováno v:
Journal of Medicinal Chemistry; Aug2015, Vol. 58 Issue 15, p6248-6263, 16p