Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Amelie, Forest"'
Autor:
Yiwen Li, Carmine Carpenito, George Wang, David Surguladze, Amelie Forest, Maria Malabunga, Mary Murphy, Yiwei Zhang, Andreas Sonyi, Darin Chin, Douglas Burtrum, Ivan Inigo, Anthony Pennello, Leyi Shen, Laurent Malherbe, Xinlei Chen, Gerald Hall, Jaafar N. Haidar, Dale L. Ludwig, Ruslan D. Novosiadly, Michael Kalos
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Modulation of the PD-1/PD-L1 axis through antagonist antibodies that block either receptor or ligand has been shown to reinvigorate the function of tumor-specific T cells and unleash potent anti-tumor immunity, leading to durable
Externí odkaz:
https://doaj.org/article/23eb068b1c80433fb11267b151e41edf
Autor:
David A. Schaer, Richard P. Beckmann, Jack A. Dempsey, Lysiane Huber, Amelie Forest, Nelusha Amaladas, Yanxia Li, Ying Cindy Wang, Erik R. Rasmussen, Darin Chin, Andrew Capen, Carmine Carpenito, Kirk A. Staschke, Linda A. Chung, Lacey M. Litchfield, Farhana F. Merzoug, Xueqian Gong, Philip W. Iversen, Sean Buchanan, Alfonso de Dios, Ruslan D. Novosiadly, Michael Kalos
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 2978-2994 (2018)
Summary: Abemaciclib, an inhibitor of cyclin dependent kinases 4 and 6 (CDK4/6), has recently been approved for the treatment of hormone receptor-positive breast cancer. In this study, we use murine syngeneic tumor models and in vitro assays to inves
Externí odkaz:
https://doaj.org/article/1595454cd7fc4830988cdc917336d3e6
Autor:
Michael Kalos, Gregory D. Plowman, Dale L. Ludwig, Ruslan D. Novosiadly, Douglas Burtrum, Yiwei Zhang, Prachi Sharma, Lauren Boucher, Michael Topper, Andreas Sonyi, Darin Chin, Xinlei Chen, Amelie Forest, Anthony L. Pennello, Ivan Inigo, Leyi Shen, Colleen Burns, Jaafar N. Haidar, David Surguladze, Jingxing Li, Juqun Shen, Carmine Carpenito, Maria B. Lebron, Rose Marie Sattler, Helen Kotanides
Figure S9 shows antitumor efficacy of combination therapy in the L55 NSCLC tumor xenograft model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e0befc3cf257f3da5e314069cd7d7a
https://doi.org/10.1158/1535-7163.22519392.v1
https://doi.org/10.1158/1535-7163.22519392.v1
Autor:
Kathryn M. Ferguson, Ruslan D. Novosiadly, Yang Shen, Amelie Forest, Jason M. Walker, Michelle D. Iacolina, Michael Topper, Michal Vieth, Scott W. Eastman, Jaafar N. Haidar, Atrish Bagchi
Supplementary Table S1 - Therapeutic antibody induced EGFR ECR mutations; Supplementary Table S2 - Mean SPR KD values for binding of wild type (WT) and cetuximab resistance variants of sEGFR to immobilized Fab fragments from cetuximab (FabC225) and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d92447c8e255cf0b039b66a1add238
https://doi.org/10.1158/1535-7163.22510134
https://doi.org/10.1158/1535-7163.22510134
Autor:
Michael Kalos, Gregory D. Plowman, Dale L. Ludwig, Ruslan D. Novosiadly, Douglas Burtrum, Yiwei Zhang, Prachi Sharma, Lauren Boucher, Michael Topper, Andreas Sonyi, Darin Chin, Xinlei Chen, Amelie Forest, Anthony L. Pennello, Ivan Inigo, Leyi Shen, Colleen Burns, Jaafar N. Haidar, David Surguladze, Jingxing Li, Juqun Shen, Carmine Carpenito, Maria B. Lebron, Rose Marie Sattler, Helen Kotanides
Table S2 shows human immune effector ADCC and CDC activity EC50 (nM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a7d8844ae274ecd96486d49338c0e0
https://doi.org/10.1158/1535-7163.22519383
https://doi.org/10.1158/1535-7163.22519383
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Tables 1-2 & Figures 1-4. Supplemental Table 1. Total IR, IR-A, IR-B, IGF-IR, IGF-I and IGF-II mRNA expression in preclinical models of pediatric solid tumors. Supplemental Table 2. Patient-derived xenograft models of lung adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a081c5e60efb4377fed1664d1b1a0c24
https://doi.org/10.1158/1541-7786.22511881.v1
https://doi.org/10.1158/1541-7786.22511881.v1
Autor:
Michael Kalos, Gregory D. Plowman, Dale L. Ludwig, Ruslan D. Novosiadly, Douglas Burtrum, Yiwei Zhang, Prachi Sharma, Lauren Boucher, Michael Topper, Andreas Sonyi, Darin Chin, Xinlei Chen, Amelie Forest, Anthony L. Pennello, Ivan Inigo, Leyi Shen, Colleen Burns, Jaafar N. Haidar, David Surguladze, Jingxing Li, Juqun Shen, Carmine Carpenito, Maria B. Lebron, Rose Marie Sattler, Helen Kotanides
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20e7787d1efd66b5f6dc06f92584d9f
https://doi.org/10.1158/1535-7163.22519389
https://doi.org/10.1158/1535-7163.22519389
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Information. This file contains Supplemental Materials and Methods, Tables and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c646aa5b0835e16453e5cd8af32839
https://doi.org/10.1158/1541-7786.22511884
https://doi.org/10.1158/1541-7786.22511884
Autor:
Paul Haluska, Dmitri Grebennik, Jan Cosaert, Tuan S. Nguyen, Amelie Forest, Ruslan Novosiadly, Shande Tang, Hagop Youssoufian, Gary N. Schwartz, Donald W. Northfelt, Ellen Chuang, Joseph A. Sparano, Rachel Layman, Denise A. Yardley, William J. Gradishar
The distributions of mRNA gene expression levels IGF-1R, Total IR, IR-A, and IR-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222c1f489d77cbb5804e0f9132e213dc
https://doi.org/10.1158/1078-0432.22458794
https://doi.org/10.1158/1078-0432.22458794
Autor:
Sheng-Bin Peng, Gregory D. Plowman, Ramon V. Tiu, James R. Henry, Amit Aggarwal, Jason C. Ting, Steven Bray, Philip Ebert, Yue Wang Webster, Ruslan D. Novosiadly, Amelie Forest, Robert D. Van Horn, Youyan Zhang, Philip W. Iversen, Gregory P. Donoho, Yung-mae M. Yao
Purpose: To evaluate the antitumor efficacy of cetuximab in combination with LSN3074753, an analog of LY3009120 and pan-RAF inhibitor in 79 colorectal cancer patient-derived xenograft (PDX) models.Experimental Design: Seventy-nine well-characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cd051fadba964dc0ea8b343c15323d
https://doi.org/10.1158/1078-0432.c.6527070
https://doi.org/10.1158/1078-0432.c.6527070