Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Amelia Tesone"'
Autor:
Melanie Rutkowski, Tom Stephen, Michael Allegrezza, Nikolaos Svoronos, Alfredo Perales-Puchalt, Amelia Tesone, Jenny Nguyen, Julia Tchou, Jose Conejo-Garcia
Publikováno v:
The Journal of Immunology. 192:133.4-133.4
The dominant R392X TLR5 polymorphism abrogates flagellin responses in >7% of humans. We report that TLR5 recognition of commensal bacteria at intestinal surfaces influences malignant progression at distal (extra-mucosal) locations through the initiat
Autor:
Nikolaos Svoronos, Michael Allegrezza, Jenny Nguyen, Alfredo Perales-Puchalt, Melanie Rutkowski, Tom Stephen, Amelia Tesone, Jose Conejo-Garcia
Publikováno v:
The Journal of Immunology. 192:203.25-203.25
Estradiol is a pleiotropic steroid hormone that regulates homeostasis, cell growth, and the immune system. In estrogen receptor positive breast cancer, anti-estrogen therapies are used to inhibit tumor cell growth. However, estrogen receptor α is al
Autor:
Michael Allegrezza, Melanie Rutkowski, Tom Stephen, Nikos Svoronos, Amelia Tesone, Jose Conejo-Garcia
Publikováno v:
The Journal of Immunology. 190:132.4-132.4
Much attention has been given to the idea of personalized cancer treatment, where the oncogenes driving tumor growth can be identified in each patient and targeted with specific molecular therapies. Many targeted inhibitors are in clinical developmen
Autor:
Melanie Rutkowski, Ximena Escovar-Fadul, Fahmida Sarmin, Tom Stephen, Michael Allegrezza, Oswaldo Gil-Guerva, Amelia Tesone, Jose Conejo-Garcia
Publikováno v:
The Journal of Immunology. 188:162.48-162.48
It has been reported that up to 25% of the human population carries a dominant point mutation in TLR5 resulting in the loss of TLR5 signaling. TLR5 expression is paramount in modulating the balance of regulatory FoxP3+ and proinflamatory IL-17+ T cel