Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amelia T. Soderholm"'
Autor:
Lisa Bohlmann, David M. P. De Oliveira, Ibrahim M. El-Deeb, Erin B. Brazel, Nichaela Harbison-Price, Cheryl-lynn Y. Ong, Tania Rivera-Hernandez, Scott A. Ferguson, Amanda J. Cork, Minh-Duy Phan, Amelia T. Soderholm, Mark R. Davies, Graeme R. Nimmo, Gordon Dougan, Mark A. Schembri, Gregory M. Cook, Alastair G. McEwan, Mark von Itzstein, Christopher A. McDevitt, Mark J. Walker
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT The World Health Organization reports that antibiotic-resistant pathogens represent an imminent global health disaster for the 21st century. Gram-positive superbugs threaten to breach last-line antibiotic treatment, and the pharmaceutical in
Externí odkaz:
https://doaj.org/article/16f22ff0c7c045db9913512c7d5962de
Autor:
Amelia T. Soderholm, Timothy C. Barnett, Othmar Korn, Tania Rivera-Hernandez, Lisa M. Seymour, Benjamin L. Schulz, Victor Nizet, Christine A. Wells, Matthew J. Sweet, Mark J. Walker
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Streptococcus pyogenes (Group A Streptococcus; GAS) commonly causes pharyngitis in children and adults, with severe invasive disease and immune sequelae being an infrequent consequence. The ability of GAS to invade the host and establish infection li
Externí odkaz:
https://doaj.org/article/902a0097b42947449aa99e9b9f492618
Autor:
Benjamin S. Beresford-Jones, Samuel C. Forster, Mark D. Stares, George Notley, Elisa Viciani, Hilary P. Browne, Daniel J. Boehmler, Amelia T. Soderholm, Nitin Kumar, Kevin Vervier, Justin R. Cross, Alexandre Almeida, Trevor D. Lawley, Virginia A. Pedicord
Publikováno v:
Cell Host & Microbe
Summary Human health and disease have increasingly been shown to be impacted by the gut microbiota, and mouse models are essential for investigating these effects. However, the compositions of human and mouse gut microbiotas are distinct, limiting tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b788fd70c50baa6c4e252ed917bbba16
Autor:
Samuel C, Forster, Simon, Clare, Benjamin S, Beresford-Jones, Katherine, Harcourt, George, Notley, Mark D, Stares, Nitin, Kumar, Amelia T, Soderholm, Anne, Adoum, Hannah, Wong, Bélen, Morón, Cordelia, Brandt, Gordon, Dougan, David J, Adams, Kevin J, Maloy, Virginia A, Pedicord, Trevor D, Lawley
Publikováno v:
Nature microbiology. 7(4)
Experimental mouse models are central to basic biomedical research; however, variability exists across genetically identical mice and mouse facilities making comparisons difficult. Whether specific indigenous gut bacteria drive immunophenotypic varia
Autor:
Tania Rivera-Hernandez, Christopher A. McDevitt, Mark J. Walker, Gordon Dougan, Gregory M. Cook, Alastair G. McEwan, Cheryl-lynn Y. Ong, Ibrahim M. El-Deeb, Mark A. Schembri, Minh-Duy Phan, Amelia T. Soderholm, Graeme R. Nimmo, Scott A. Ferguson, Lisa Bohlmann, Nichaela Harbison-Price, Mark von Itzstein, Erin B. Brazel, David M. P. De Oliveira, Amanda J. Cork, Mark R. Davies
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
mBio, Vol 9, Iss 6, p e02391-18 (2018)
mBio
mBio, Vol 9, Iss 6, p e02391-18 (2018)
mBio
The rise of bacterial antibiotic resistance coupled with a reduction in new antibiotic development has placed significant burdens on global health care. Resistant bacterial pathogens such as methicillin-resistant Staphylococcus aureus and vancomycin-
Publikováno v:
The Journal of Immunology. 206:100.10-100.10
Peripheral CD4+CD8αα+TCRαβ+ intraepithelial lymphocytes (pIELs) are a specialised T cell population that require the presence of intestinal microbes for their development, however the microbes and factors involved are not well characterised. pIEL
A specific microbial metabolite influences the development of peripheral intraepithelial lymphocytes
Publikováno v:
The Journal of Immunology. 204:230.2-230.2
Peripheral CD4+CD8αα+TCRαβ+ intraepithelial lymphocytes (pIELs) are a specialised T cell population that are reduced in germ-free (GF) C57BL/6 mice and vary in frequency between SPF mice from different sources, indicating their development is dep
Autor:
Amelia T. Soderholm, Mark J. Walker
Publikováno v:
Cell Syst
Group A Streptococcus (GAS) remains a top 10 deadliest human pathogen worldwide despite its sensitivity to penicillin. Although the most common GAS infection is pharyngitis (strep throat), it also causes life-threatening systemic infections. A series
Autor:
Amelia T, Soderholm, Timothy C, Barnett, Othmar, Korn, Tania, Rivera-Hernandez, Lisa M, Seymour, Benjamin L, Schulz, Victor, Nizet, Christine A, Wells, Matthew J, Sweet, Mark J, Walker
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Streptococcus pyogenes (Group A Streptococcus; GAS) commonly causes pharyngitis in children and adults, with severe invasive disease and immune sequelae being an infrequent consequence. The ability of GAS to invade the host and establish infection li
Publikováno v:
Journal of leukocyte biology. 103(2)
Streptococcus pyogenes, the Group A Streptococcus (GAS), is the most common cause of bacterial pharyngitis in children and adults. Innate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central