Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Amelia Strom"'
Autor:
William G. Mantyh, J. Nicholas Cochran, Jared W. Taylor, Iris J. Broce, Ethan G. Geier, Luke W. Bonham, Ashlyn G. Anderson, Daniel W. Sirkis, Renaud La Joie, Leonardo Iaccarino, Kiran Chaudhary, Lauren Edwards, Amelia Strom, Harli Grant, Isabel E. Allen, Zachary A. Miller, Marilu L. Gorno‐Tempini, Joel H. Kramer, Bruce L. Miller, Rahul S. Desikan, Gil D. Rabinovici, Jennifer S. Yokoyama
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract Early‐onset Alzheimer's disease (AD) is highly heritable, yet only 10% of cases are associated with known pathogenic mutations. For early‐onset AD patients without an identified autosomal dominant cause, we hypothesized that their early
Externí odkaz:
https://doaj.org/article/4906107fb48d48b98f50a0cb0d77e800
Autor:
Kamalini G Ranasinghe, Parul Verma, Chang Cai, Xihe Xie, Kiwamu Kudo, Xiao Gao, Hannah Lerner, Danielle Mizuiri, Amelia Strom, Leonardo Iaccarino, Renaud La Joie, Bruce L Miller, Maria Luisa Gorno-Tempini, Katherine P Rankin, William J Jagust, Keith Vossel, Gil D Rabinovici, Ashish Raj, Srikantan S Nagarajan
Publikováno v:
eLife, Vol 11 (2022)
Background: Neuronal- and circuit-level abnormalities of excitation and inhibition are shown to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer’s disease (AD). These relationships remain poorly understood in patient
Externí odkaz:
https://doaj.org/article/c6b8e7b481034efd8dbc138785f58b65
Autor:
Elena Tsoy, Amelia Strom, Leonardo Iaccarino, Sabrina J. Erlhoff, Collette A. Goode, Anne-Marie Rodriguez, Gil D. Rabinovici, Bruce L. Miller, Joel H. Kramer, Katherine P. Rankin, Renaud La Joie, Katherine L. Possin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract Background β-amyloid (Aβ) and tau positron emission tomography (PET) detect the pathological changes that define Alzheimer’s disease (AD) in living people. Cognitive measures sensitive to Aβ and tau burden may help streamline identifica
Externí odkaz:
https://doaj.org/article/543a1b6a6bd24d7da165623259f2b21f
Autor:
Lawren VandeVrede, Daniel M Gibbs, Mary Koestler, Renaud La Joie, Peter A. Ljubenkov, Karine Provost, David Soleimani‐Meigooni, Amelia Strom, Elena Tsoy, Gil D. Rabinovici, Adam L. Boxer
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Amyloid‐related imaging abnormalities (ARIA) are a common, dose‐dependent effect of amyloid‐targeting antibodies, strongly associated with the apolipoprotein E (APOE) ε4 allele. Methods We describe the clinical course and
Externí odkaz:
https://doaj.org/article/07cc145fe44243f48d661703dbfe5cb3
Autor:
Elena Tsoy, Sabrina J. Erlhoff, Collette A. Goode, Karen A. Dorsman, Suchanan Kanjanapong, Cutter A. Lindbergh, Renaud La Joie, Amelia Strom, Gil D. Rabinovici, Serggio C. Lanata, Bruce L. Miller, Sarah E. Tomaszewski Farias, Joel H. Kramer, Katherine P. Rankin, Katherine L. Possin
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Composite scores based on psychometrically rigorous cognitive assessments are well suited for early diagnosis and disease monitoring. Methods We developed and cross‐validated the Brain Health Assessment‐Cognitive Score (BHA
Externí odkaz:
https://doaj.org/article/e3660d6a663b43b2bd490a54b0800fc7
Autor:
Jeremy A Tanner, Leonardo Iaccarino, Lauren Edwards, Breton M Asken, Maria L Gorno-Tempini, Joel H Kramer, Julie Pham, David C Perry, Katherine Possin, Maura Malpetti, Taylor Mellinger, Bruce L Miller, Zachary Miller, Nidhi S Mundada, Howard J Rosen, David N Soleimani-Meigooni, Amelia Strom, Renaud La Joie, Gil D Rabinovici
Publikováno v:
Brain
Early-onset (age < 65) Alzheimer’s disease is associated with greater non-amnestic cognitive symptoms and neuropathological burden than late-onset disease. It is not fully understood whether these groups also differ in the associations between mole
Autor:
Julie Pham, Renaud La Joie, Amelia Strom, Lauren Edwards, Harli Grant, Joel H. Kramer, Taylor J. Mellinger, Katherine L. Possin, Yann Cobigo, David N Soleimani-Meigooni, Suzanne L. Baker, Bruce L. Miller, Amy Wolf, Leonardo Iaccarino, Gil D. Rabinovici, Kaitlin B. Casaletto, Howard J. Rosen, Minseon Kim
Publikováno v:
Neurobiol Aging
We assessed sex differences in amyloid- and tau-PET retention in 119 amyloid positive patients with mild cognitive impairment or Alzheimer’s disease (AD) dementia. Patients underwent 3T-MRI, (11)C-PIB amyloid-PET and (18)F-Flortaucipir tau-PET. Lin
Autor:
Lawren VandeVrede, Amy Wolf, Elisabeth H. Thijssen, Joel H. Kramer, Howard J. Rosen, Renaud La Joie, Corrina Fonseca, Kaj Blennow, Yann Cobigo, Andreas Jeromin, Marie-Anne Valentin, Adam L. Boxer, Oskar Hansson, Lili Yu, Salvatore Spina, Niklas Mattsson-Carlgren, Amelia Strom, Bradley F. Boeve, Bruce L. Miller, Charlotte E. Teunissen, Jeffrey L. Dage, William W. Seeley, Lea T. Grinberg, Arvind Kinhikar, Gil D. Rabinovici, Argentina Lario Lago, Agnieszka Kieloch, Leonardo Iaccarino, Nicholas K. Proctor, Treatment for Frontotemporal Lobar Degeneration investigators, Rajeev Sivasankaran, Hilary W. Heuer, Julio C. Rojas, Danielle Graham, Suzanne L. Baker, Isabel E. Allen, Henrik Zetterberg
Publikováno v:
The Lancet Neurology, 20(9), 739-752. Lancet Publishing Group
Advancing Research and Treatment for Frontotemporal Lobar Degeneration investigators 2021, ' Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study ', The Lancet Neurology, vol. 20, no. 9, pp. 739-752 . https://doi.org/10.1016/S1474-4422(21)00214-3
The Lancet. Neurology, vol 20, iss 9
Advancing Research and Treatment for Frontotemporal Lobar Degeneration investigators 2021, ' Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study ', The Lancet Neurology, vol. 20, no. 9, pp. 739-752 . https://doi.org/10.1016/S1474-4422(21)00214-3
The Lancet. Neurology, vol 20, iss 9
Background: Plasma tau phosphorylated at threonine 217 (p-tau217) and plasma tau phosphorylated at threonine 181 (p-tau181) are associated with Alzheimer's disease tau pathology. We compared the diagnostic value of both biomarkers in cognitively unim
Autor:
Maurits Johansson, William G. Mantyh, Renaud La Joie, Sandeep S.V. Golla, Pontus Tideman, Amelia Strom, John C. van Swieten, Ellen H. Singleton, Anke A. Dijkstra, Evi Berendrecht, Philip Scheltens, Emma M. Coomans, Antoine Leuzy, Rik Ossenkoppele, Gil D. Rabinovici, Emma E. Wolters, Leonardo Iaccarino, Erik Stomrud, Hayel Tuncel, Janne M. Papma, Lauren Edwards, Bart N.M. van Berckel, Olof Strandberg, Femke H. Bouwman, Oskar Hansson, Bruce L. Miller, Ruben Smith, Denise Visser, Yolande A.L. Pijnenburg
Publikováno v:
Journal of Neurology, Neurosurgery and Psychiatry, 92(8), 872-880. BMJ Publishing Group
Journal of neurology, neurosurgery, and psychiatry, vol 92, iss 8
Journal of Neurology, Neurosurgery, and Psychiatry
Singleton, E, Hansson, O, Pijnenburg, Y A L, la Joie, R, Mantyh, W G, Tideman, P, Stomrud, E, Leuzy, A, Johansson, M, Strandberg, O, Smith, R, Berendrecht, E, Miller, B L, Iaccarino, L, Edwards, L, Strom, A, Wolters, E E, Coomans, E, Visser, D, Golla, S S V, Tuncel, H, Bouwman, F, van Swieten, J C, Papma, J M, van Berckel, B, Scheltens, P, Dijkstra, A A, Rabinovici, G D & Ossenkoppele, R 2021, ' Heterogeneous distribution of tau pathology in the behavioural variant of Alzheimer's disease ', Journal of Neurology, Neurosurgery and Psychiatry, vol. 92, no. 8, pp. 872-880 . https://doi.org/10.1136/jnnp-2020-325497
Journal of neurology, neurosurgery, and psychiatry, vol 92, iss 8
Journal of Neurology, Neurosurgery, and Psychiatry
Singleton, E, Hansson, O, Pijnenburg, Y A L, la Joie, R, Mantyh, W G, Tideman, P, Stomrud, E, Leuzy, A, Johansson, M, Strandberg, O, Smith, R, Berendrecht, E, Miller, B L, Iaccarino, L, Edwards, L, Strom, A, Wolters, E E, Coomans, E, Visser, D, Golla, S S V, Tuncel, H, Bouwman, F, van Swieten, J C, Papma, J M, van Berckel, B, Scheltens, P, Dijkstra, A A, Rabinovici, G D & Ossenkoppele, R 2021, ' Heterogeneous distribution of tau pathology in the behavioural variant of Alzheimer's disease ', Journal of Neurology, Neurosurgery and Psychiatry, vol. 92, no. 8, pp. 872-880 . https://doi.org/10.1136/jnnp-2020-325497
ObjectiveThe clinical phenotype of the rare behavioural variant of Alzheimer’s disease (bvAD) is insufficiently understood. Given the strong clinico-anatomical correlations of tau pathology in AD, we investigated the distribution of tau deposits in
Autor:
Kamalini G Ranasinghe, Parul Verma, Chang Cai, Xihe Xie, Kiwamu Kudo, Xiao Gao, Hannah Lerner, Danielle Mizuiri, Amelia Strom, Leonardo Iaccarino, Renaud La Joie, Bruce L Miller, Maria Luisa Gorno-Tempini, Katherine P Rankin, William J Jagust, Keith Vossel, Gil D Rabinovici, Ashish Raj, Srikantan S Nagarajan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb1e9f5cb4df22904be6d1edadae290e
https://doi.org/10.7554/elife.77850.sa2
https://doi.org/10.7554/elife.77850.sa2