Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Amelia Scheck"'
Autor:
Chunyan Gao, Jocelyn A. Schroeder, Feng Xue, Weiqing Jing, Yuanhua Cai, Amelia Scheck, Saravanan Subramaniam, Sridhar Rao, Hartmut Weiler, Agnieszka Czechowicz, Qizhen Shi
Publikováno v:
Blood Advances, Vol 3, Iss 18, Pp 2700-2711 (2019)
Gene therapy offers the potential to cure hemophilia A (HA). We have shown that hematopoietic stem cell (HSC)–based platelet-specific factor VIII (FVIII) (2bF8) gene therapy can produce therapeutic protein and induce antigen-specific immune toleran
Externí odkaz:
https://doaj.org/article/83420e9f07c946c78fd2d34f6a0da735
Autor:
Agnieszka Czechowicz, Rahul Palchaudhuri, Amelia Scheck, Yu Hu, Jonathan Hoggatt, Borja Saez, Wendy W. Pang, Michael K. Mansour, Tiffany A. Tate, Yan Yi Chan, Emily Walck, Gerlinde Wernig, Judith A. Shizuru, Florian Winau, David T. Scadden, Derrick J. Rossi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Hematopoietic stem cell (HSC) transplantation is a desirable treatment for many non-malignant and malignant diseases, but its use requires preconditioning of recipients with irradiation or chemotherapy that often induces high toxicity. Here the autho
Externí odkaz:
https://doaj.org/article/9ffac621975f4bccb6eaeafd10b5ba55
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Transplantation of allogeneic bone marrow helps establish chimerism that may induce tolerance to tissue grafts. Here the authors show that a CD117-antibody-drug-conjugate helps precondition the recipients for inducing mixed chimerism and allo-toleran
Externí odkaz:
https://doaj.org/article/2dddc27bdce0404992038db99358a2da
Autor:
Rajni Agarwal, Alice Bertaina, Rofida Nofal, Gopin Saini, Nivedita Kunte, Sushmita Sen, Yan Yi Chan, Hana Willner, Matthias Felber, Mark R. Krampf, Maite Van Hentenryck, Emily Walck, Amelia Scheck, Supawat Thongthip, Aaron C. Logan, Kirstin Dougall, Alisha Bouge, Jaap Jan Boelens, Janel Renee Long-Boyle, Robertson Parkman, Irving L Weissman, Judith A. Shizuru, Wendy W. Pang, Maria Grazia Roncarolo, Matthew H. Porteus, Agnieszka Czechowicz
Publikováno v:
Transplantation and Cellular Therapy. 29:S163-S164
Autor:
Yan Yi Chan, Rofida Nofal, Pui Yan Ho, Supawat Thongthip, Maire Rayburn, Leah Swartzrock, Amelia Scheck, Kenneth I Weinberg, Agnieszka Czechowicz
Publikováno v:
Transplantation and Cellular Therapy. 28:S234-S235
Autor:
Tiffany A. Tate, David T. Scadden, Emily Walck, Judith A. Shizuru, Rahul Palchaudhuri, Yu Hu, Jonathan Hoggatt, Wendy W. Pang, Amelia Scheck, Yan-Yi Chan, Michael K. Mansour, Borja Saez, Agnieszka Czechowicz, Derrick J. Rossi, Florian Winau, Gerlinde Wernig
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Hematopoietic stem cell transplantation (HSCT) is a curative therapy for blood and immune diseases with potential for many settings beyond current standard-of-care. Broad HSCT application is currently precluded largely due to morbidity and mortality
Autor:
Feng Xue, Chunyan Gao, Jocelyn A. Schroeder, Sridhar Rao, Yuanhua Cai, Hartmut Weiler, Amelia Scheck, Agnieszka Czechowicz, Qizhen Shi, Weiqing Jing, Saravanan Subramaniam
Gene therapy offers the potential to cure hemophilia A (HA). We have shown that hematopoietic stem cell (HSC)–based platelet-specific factor VIII (FVIII) (2bF8) gene therapy can produce therapeutic protein and induce antigen-specific immune toleran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b913e1ab50330ba40f8abb181b3f758
https://europepmc.org/articles/PMC6759737/
https://europepmc.org/articles/PMC6759737/
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Hematopoietic chimerism after allogeneic bone marrow transplantation may establish a state of donor antigen-specific tolerance. However, current allotransplantation protocols involve genotoxic conditioning which has harmful side-effects and predispos
Autor:
Derrick J. Rossi, Yu Hu, Borja Saez, Michael K. Mansour, David T. Scadden, Rahul Palchaudhuri, Jonathan Hoggatt, Amelia Scheck, David B. Sykes, Agnieszka Czechowicz, Florian Winau
Publikováno v:
Biology of Blood and Marrow Transplantation. 24:S60-S61
Autor:
Rahul Palchaudhuri, Borja Saez, Derrick J. Rossi, Agnieszka Czechowicz, David T. Scadden, Jonathan Hoggatt, Amelia Scheck
Publikováno v:
Blood. 128:493-493
Bone marrow/hematopoietic stem cell transplantation (BMT/HSCT) holds the remarkable ability to correct any blood or immune disease. Unfortunately, despite the tremendous potential of this procedure, BMT remains fairly limited in part due to the sever