Výsledky vyhledávání - "Amelia S. Power"

Akademický článek

The Monocrotaline Rat Model of Right Heart Disease Induced by Pulmonary Artery Hypertension

Autor: Anna Maria Krstic, Timothy L. M. Jones, Amelia S. Power, Marie-Louise Ward

Publikováno v: Biomedicines, Vol 12, Iss 9, p 1944 (2024)

Pulmonary artery hypertension (PAH) is characterised by increased pulmonary vascular resistance (PVR) resulting in elevated pressure in the pulmonary artery supplying the pulmonary circulation. Disease of the right ventricle (RV) often manifests as a

Externí odkaz: https://doaj.org/article/c5dde76abc2e408abdde820a03d673b5

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Akademický článek

Increased Mitochondrial Calcium Fluxes in Hypertrophic Right Ventricular Cardiomyocytes from a Rat Model of Pulmonary Artery Hypertension

Autor: Anna Maria Krstic, Amelia S. Power, Marie-Louise Ward

Publikováno v: Life, Vol 13, Iss 2, p 540 (2023)

Pulmonary artery hypertension causes right ventricular hypertrophy which rapidly progresses to heart failure with underlying cardiac mitochondrial dysfunction. Prior to failure, there are alterations in cytosolic Ca2+ handling that might impact mitoc

Externí odkaz: https://doaj.org/article/74cbefb4ba284bafbf048165676c0a36

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Akademický článek

CaMKII Inhibition is a Novel Therapeutic Strategy to Prevent Diabetic Cardiomyopathy

Autor: Christopher R. Veitch, Amelia S. Power, Jeffrey R. Erickson

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Increasing prevalence of diabetes mellitus worldwide has pushed the complex disease state to the foreground of biomedical research, especially concerning its multifaceted impacts on the cardiovascular system. Current therapies for diabetic cardiomyop

Externí odkaz: https://doaj.org/article/488cd6ad52b846b9a79a72da0c5ff58d

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Akademický článek

Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment.

Autor: Amelia S Power, Ruth Norman, Timothy L M Jones, Anthony J Hickey, Marie-Louise Ward

Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214740 (2019)

Pulmonary hypertension (PH) increases the work of the right ventricle (RV) and causes right-sided heart failure. This study examined RV mitochondrial function and ADP transfer in PH animals advancing to right heart failure, and investigated a potenti

Externí odkaz: https://doaj.org/article/2423faa97a574a92b96406869f70202a

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Treadmill running increases the calcium sensitivity of myofilaments in diabetic rats

Autor: Angela C. Greenman, Gary M. Diffee, Amelia S. Power, Gerard T. Wilkins, Olivia M. S. Gold, Jeffrey R. Erickson, James C. Baldi

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 132(6)

The cardiovascular benefits of regular exercise are unequivocal, yet patients with type 2 diabetes respond poorly to exercise due to a reduced cardiac reserve. The contractile response of diabetic cardiomyocytes to β-adrenergic stimulation is attenu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5acabcef55765dd4817660c784bb12
https://pubmed.ncbi.nlm.nih.gov/35482324

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