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Akademický článek

Development, Diversity, and Neurogenic Capacity of Enteric Glia

Autor: Werend Boesmans, Amelia Nash, Kinga R. Tasnády, Wendy Yang, Lincon A. Stamp, Marlene M. Hao

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2022)

Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the “support” cells of the enteric nervous system, studies over the past 20 years have unveiled a vast array of functions carried out by enteric glia. The

Externí odkaz: https://doaj.org/article/cf562227fe424e5c90f1faaf1ca0a3f4

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BACE inhibitor treatment of mice induces hyperactivity in a Seizure-related gene 6 family dependent manner without altering learning and memory

Autor: Stefan F. Lichtenthaler, Brian Joel Hrupka, H. J. M. Gijsen, Hiroshi Takeshima, Kathleen Sue Lyn Teng, Jenny M. Gunnersen, Kathryn M. Munro, Amelia Nash

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific reports 11(1), 15084 (2021). doi:10.1038/s41598-021-94369-0
Scientific Reports

BACE inhibitors, which decrease BACE1 (β-secretase 1) cleavage of the amyloid precursor protein, are a potential treatment for Alzheimer’s disease. Clinical trials using BACE inhibitors have reported a lack of positive effect on patient symptoms a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e0ac5c9959bc4bfafc3fcfeb50f8b7
https://doaj.org/article/30fc73a123fe4f83943a0c12121c8a83

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Lack of Sez6 Family Proteins Impairs Motor Functions, Short-Term Memory, and Cognitive Flexibility and Alters Dendritic Spine Properties

Autor: Hiroshi Takeshima, Jenny M. Gunnersen, Martina Pigoni, Stefan F. Lichtenthaler, Tim D. Aumann, Kathryn M. Munro, Amelia Nash

Publikováno v: Cerebral cortex 30(4), 2167-2184 (2019). doi:10.1093/cercor/bhz230

Seizure-related gene 6 (Sez6), Sez6-Like (Sez6L), and Sez6-Like 2 (Sez6L2) comprise a family of homologous proteins widely expressed throughout the brain that have been linked to neurodevelopmental and psychiatric disorders. Here, we use Sez6 triple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98c8c55ac4b13c04924db59f031ea9f
https://doi.org/10.1093/cercor/bhz230

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BACE Inhibitor Treatment in Mice Induces Hyperactivity in a Seizure-Related Gene 6 Family Protein Dependent Manner but Does Not alter Spatial Learning and Reference Memory

Autor: Brian Joel Hrupka, H. J. M. Gijsen, Hiroshi Takeshima, Amelia Nash, Kathryn M. Munro, K. S-L. Teng, Jenny M. Gunnersen, Stefan F. Lichtenthaler

BackgroundBACE inhibitors, which decrease BACE1 (β-secretase 1) cleavage of the amyloid precursor protein, are a potential treatment for Alzheimer’s disease. Clinical trials using BACE inhibitors have reported a lack of positive effect on patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee73d7f53e2f0fe3a2f62895a01a9612
https://doi.org/10.21203/rs.3.rs-396650/v1

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Functions of the Alzheimer’s Disease Protease BACE1 at the Synapse in the Central Nervous System

Autor: Martina Pigoni, Amelia Nash, Stefan F. Lichtenthaler, Jenny M. Gunnersen, Kathryn M. Munro

Publikováno v: Journal of molecular neuroscience 60(3), 305-315 (2016). doi:10.1007/s12031-016-0800-1
Journal of Molecular Neuroscience

Inhibition of the protease β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is a promising treatment strategy for Alzheimer’s disease, and a number of BACE inhibitors are currently progressing through clinical trials. The strategy aims t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adda334c22c7bd7f4b3bb549af990b16
https://doi.org/10.1007/s12031-016-0800-1

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Intercultural learning in modern language education: expanding meaning-making potentials

Autor: Amelia Nash

Publikováno v: Language and Intercultural Communication. 17:81-83

Kearney’s most recent contribution to the field of intercultural learning provides insight into the processes of deep cultural engagement and the extension of ‘meaning-making potentials’ (p. 4) on ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27e2a1fd16d9e462b2716ea378541a95
https://doi.org/10.1080/14708477.2016.1201917

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