Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Amelia N, Deitchman"'
Autor:
Michael J. Peluso, Tyler-Marie Deveau, Sadie E. Munter, Dylan Ryder, Amanda Buck, Gabriele Beck-Engeser, Fay Chan, Scott Lu, Sarah A. Goldberg, Rebecca Hoh, Viva Tai, Leonel Torres, Nikita S. Iyer, Monika Deswal, Lynn H. Ngo, Melissa Buitrago, Antonio Rodriguez, Jessica Y. Chen, Brandon C. Yee, Ahmed Chenna, John W. Winslow, Christos J. Petropoulos, Amelia N. Deitchman, Joanna Hellmuth, Matthew A. Spinelli, Matthew S. Durstenfeld, Priscilla Y. Hsue, J. Daniel Kelly, Jeffrey N. Martin, Steven G. Deeks, Peter W. Hunt, Timothy J. Henrich
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
BACKGROUND The presence and reactivation of chronic viral infections, such as EBV, CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but studies in well-characterized postacute cohorts of individuals with COVID-19 over a
Externí odkaz:
https://doaj.org/article/412cbc831bfe489a8055fa7ce7beae94
Autor:
Denis R. Beckford-Vera, Robert R. Flavell, Youngho Seo, Enrique Martinez-Ortiz, Maya Aslam, Cassandra Thanh, Emily Fehrman, Marion Pardons, Shreya Kumar, Amelia N. Deitchman, Vahid Ravanfar, Brailee Schulte, I-Wei Katherine Wu, Tony Pan, Jacqueline D. Reeves, Christopher C. Nixon, Nikita S. Iyer, Leonel Torres, Sadie E. Munter, Tony Hyunh, Christos J. Petropoulos, Rebecca Hoh, Benjamin L. Franc, Lucio Gama, Richard A. Koup, John R. Mascola, Nicolas Chomont, Steven G. Deeks, Henry F. VanBrocklin, Timothy J. Henrich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, the authors apply positron emission tomography (PET) imaging to visualize HIV tissue-wide burden in infected individuals using a radiolabeled broadly neutralizing antibody, 89Zr-VRC01, and show that PET tracer lymph node uptake positively corre
Externí odkaz:
https://doaj.org/article/42a11e0860df4b12b471a443fa8f7ecb
Publikováno v:
Viruses, Vol 15, Iss 5, p 1126 (2023)
Gene-modification therapies are at the forefront of HIV-1 cure strategies. Chimeric antigen receptor (CAR)-T cells pose a potential approach to target infected cells during antiretroviral therapy or following analytical treatment interruption (ATI).
Externí odkaz:
https://doaj.org/article/e8ae42e5b7524f0b96429a0ae14449b4
Autor:
Michael J. Peluso, Amelia N. Deitchman, Leonel Torres, Nikita S. Iyer, Sadie E. Munter, Christopher C. Nixon, Joanna Donatelli, Cassandra Thanh, Saki Takahashi, Jill Hakim, Keirstinne Turcios, Owen Janson, Rebecca Hoh, Viva Tai, Yanel Hernandez, Emily A. Fehrman, Matthew A. Spinelli, Monica Gandhi, Lan Trinh, Terri Wrin, Christos J. Petropoulos, Francesca T. Aweeka, Isabel Rodriguez-Barraquer, J. Daniel Kelly, Jeffrey N. Martin, Steven G. Deeks, Bryan Greenhouse, Rachel L. Rutishauser, Timothy J. Henrich
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109518- (2021)
Summary: We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses, soluble markers of inflammation, and antibody levels and neutralization capacity longitudinally in 70 individuals with PCR-confirmed SARS-CoV
Externí odkaz:
https://doaj.org/article/3c9c02e0fee544eb9764cc9e8b79dffd
Autor:
Ashley F. George, Matthew McGregor, David Gingrich, Jason Neidleman, Rebecca S. Marquez, Kyrlia C. Young, Kaavya L. Thanigaivelan, Warner C. Greene, Phyllis C. Tien, Amelia N. Deitchman, Trimble L. Spitzer, Nadia R. Roan
Publikováno v:
Viruses, Vol 14, Iss 8, p 1723 (2022)
The efficacy of HIV pre-exposure prophylaxis (PrEP) is high in men who have sex with men, but much more variable in women, in a manner largely attributed to low adherence. This reduced efficacy, however, could also reflect biological factors. Transmi
Externí odkaz:
https://doaj.org/article/f55403f065a443fe8877ab39b32d77fa
Autor:
Amelia N. Deitchman
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 5, Pp 256-258 (2019)
Externí odkaz:
https://doaj.org/article/810bf2454ea0436c9c28dd67259ef694
Autor:
Michael J, Peluso, Tyler-Marie, Deveau, Sadie E, Munter, Dylan, Ryder, Amanda, Buck, Gabriele, Beck-Engeser, Fay, Chan, Scott, Lu, Sarah A, Goldberg, Rebecca, Hoh, Viva, Tai, Leonel, Torres, Nikita S, Iyer, Monika, Deswal, Lynn H, Ngo, Melissa, Buitrago, Antonio, Rodriguez, Jessica Y, Chen, Brandon C, Yee, Ahmed, Chenna, John W, Winslow, Christos J, Petropoulos, Amelia N, Deitchman, Joanna, Hellmuth, Matthew A, Spinelli, Matthew S, Durstenfeld, Priscilla Y, Hsue, J Daniel, Kelly, Jeffrey N, Martin, Steven G, Deeks, Peter W, Hunt, Timothy J, Henrich
Publikováno v:
The Journal of clinical investigation.
The presence and reactivation of chronic viral infections such as Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human immunodeficiency virus (HIV) have been proposed as potential contributors to Long COVID (LC), but studies in well-characterize
Autor:
Liusheng Huang, Francesca T. Aweeka, Actg Protocol Team, Amy Kantor, Amelia N. Deitchman, James H. Stein, Heather J. Ribaudo, Priscilla Y. Hsue, David Gingrich, Judith S. Currier
Publikováno v:
J Acquir Immune Defic Syndr
Journal of acquired immune deficiency syndromes (1999), vol 85, iss 5
Journal of acquired immune deficiency syndromes (1999), vol 85, iss 5
Background To mitigate increased risk of premature cardiovascular disease in antiretroviral therapy (ART) suppressed adults living with HIV (PWH), low-dose methotrexate (LDMTX) was evaluated in a multicenter randomized placebo controlled clinical tri
Autor:
Timothy J. Henrich, Amelia N. Deitchman, Joanna Donatelli, Leonel Torres, Michael J. Peluso, Cassandra Yun, Rachel L. Rutishauser, Steven G. Deeks, Sadie E. Munter, Nikita S. Iyer, Kara L. Lynch, Lindsay Ryan
Publikováno v:
Open Forum Infectious Diseases
Open forum infectious diseases, vol 8, iss 8
Open forum infectious diseases, vol 8, iss 8
We report a patient with connective tissue disease who developed modest severe acute respiratory syndrome coronavirus 2 receptor binding domain–specific antibody levels and a lack of neutralization capacity, despite having received 3 mRNA coronavir
Autor:
Denis R, Beckford-Vera, Robert R, Flavell, Youngho, Seo, Enrique, Martinez-Ortiz, Maya, Aslam, Cassandra, Thanh, Emily, Fehrman, Marion, Pardons, Shreya, Kumar, Amelia N, Deitchman, Vahid, Ravanfar, Brailee, Schulte, I-Wei Katherine, Wu, Tony, Pan, Jacqueline D, Reeves, Christopher C, Nixon, Nikita S, Iyer, Leonel, Torres, Sadie E, Munter, Tony, Hyunh, Christos J, Petropoulos, Rebecca, Hoh, Benjamin L, Franc, Lucio, Gama, Richard A, Koup, John R, Mascola, Nicolas, Chomont, Steven G, Deeks, Henry F, VanBrocklin, Timothy J, Henrich
Publikováno v:
Nature communications. 13(1)
A major obstacle to achieving long-term antiretroviral (ART) free remission or functional cure of HIV infection is the presence of persistently infected cells that establish a long-lived viral reservoir. HIV largely resides in anatomical regions that