Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Amelia Mazzone"'
Autor:
Wazim Mohammed Ismail, Amelia Mazzone, Flavia G. Ghiraldini, Jagneet Kaur, Manvir Bains, Amik Munankarmy, Monique S. Bagwell, Stephanie L. Safgren, John Moore-Weiss, Marina Buciuc, Lynzie Shimp, Kelsey A. Leach, Luis F. Duarte, Chandandeep S. Nagi, Saul Carcamo, Chi-Yeh Chung, Dan Hasson, Neda Dadgar, Jian Zhong, Jeong-Heon Lee, Fergus J. Couch, Alexander Revzin, Tamas Ordog, Emily Bernstein, Alexandre Gaspar-Maia
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
MacroH2A histone variants are shown to mark a subset of enhancers in both normal and cancer cells. In mice, macroH2A deficiency is shown to facilitate increased activity of transcription stem cell-associated transcription factors.
Externí odkaz:
https://doaj.org/article/687c1bfb1c8f4aa091d8d2f3ab0a9055
Autor:
Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern, Lorin S Milescu, Gianrico Farrugia, Arthur Beyder
Publikováno v:
eLife, Vol 12 (2023)
Voltage-gated ion channels (VGICs) orchestrate electrical activities that drive mechanical functions in contractile tissues such as the heart and gut. In turn, contractions change membrane tension and impact ion channels. VGICs are mechanosensitive,
Externí odkaz:
https://doaj.org/article/b8dfecfda4b3488889b0906796a76808
Autor:
Moritz Binder, Ryan M. Carr, Terra L. Lasho, Christy M. Finke, Abhishek A. Mangaonkar, Christopher L. Pin, Kurt R. Berger, Amelia Mazzone, Sandeep Potluri, Tamas Ordog, Keith D. Robertson, David L. Marks, Martin E. Fernandez-Zapico, Alexandre Gaspar-Maia, Mrinal M. Patnaik
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
‘Mutations in the chromatin remodeler ASXL1 (ASXL1MT) are associated with poor clinical outcome, however, their impact on chromatin dynamics remains unexplored. Here the authors use a multi-omics approach for chronic myelomonocytic leukemia (CMML)
Externí odkaz:
https://doaj.org/article/81870b2649874a6f8f41f85549083775
Autor:
Gaspar-Maia, Leticia Sandoval, Wazim Mohammed Ismail, Amelia Mazzone, Mihai Dumbrava, Jenna Fernandez, Amik Munankarmy, Terra Lasho, Moritz Binder, Vernadette Simon, Kwan Hyun Kim, Nicholas Chia, Jeong-Heon Lee, S. John Weroha, Mrinal Patnaik, Alexandre
Publikováno v:
Genes; Volume 14; Issue 6; Pages: 1245
The snATAC + snRNA platform allows epigenomic profiling of open chromatin and gene expression with single-cell resolution. The most critical assay step is to isolate high-quality nuclei to proceed with droplet-base single nuclei isolation and barcodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::2f30d1b434d7a3944ab19bc7f4c4a6f6
Autor:
Leticia Sandoval, Wazim Mohammed Ismail, Amelia Mazzone, Mihai Dumbrava, Jenna Fernandez, Amik Munankarmy, Terra Lasho, Mortiz Binder, Vernadette Simon, Kwan Hyun Kim, Nicholas Chia, Jeong Heon Lee, S. John Weroha, Mrinal M. Patnaik, Alexandre Gaspar-Maia
The snATAC + snRNA platform allows epigenomic profiling of open chromatin and gene expression with single-cell resolution. The most critical assay step is to isolate high-quality nuclei to proceed with droplet-base single nuclei isolation and barcodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f5ed61415067642dd481013a9a91a4e
https://doi.org/10.20944/preprints202305.0530.v1
https://doi.org/10.20944/preprints202305.0530.v1
Autor:
Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern, Lorin S Milescu, Gianrico Farrugia, Arthur Beyder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9b84cda371b1455221d853f6c46466
https://doi.org/10.7554/elife.79271.sa2
https://doi.org/10.7554/elife.79271.sa2
Autor:
Moritz Binder, Terra L. Lasho, Wazim Mohammed Ismail, Nana A. Ben-Crentsil, Jenna A. Fernandez, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Susan M. Schwager, Jonathan J. Harington, Melissa R. Snyder, Nathalie M. Droin, Eric Solary, Keith D. Robertson, Eric D. Wieben, Eric Padron, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik
Coronavirus disease 2019 (COVID-19) is associated with significant morbidity and mortality, albeit with considerable heterogeneity among affected individuals. It remains unclear which factors determine severity of illness and long-term outcomes. Emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ea8e91a2ed17849d0a3de97470e93e1
https://doi.org/10.1101/2022.08.25.505316
https://doi.org/10.1101/2022.08.25.505316
Autor:
Leticia Assad Maia Sandoval, Wazim Mohammed Ismail, Amelia Mazzone, Amik Munankarmy, Jagneet Kaur, Tsering Tashi, Xiaonan Hou, Nagarajan Kannan, Ann Oberg, Scott H. Kaufmann, Saravut John Weroha, Alexandre Gaspar-Maia
Publikováno v:
Cancer Research. 83:4724-4724
Ovarian cancer is one of the most common gynecologic malignancies, with high-grade serous carcinoma (HGSC) as the most frequent and deadliest type of ovarian cancer (OC). With the recent advances in cancer epigenomic profiling, it has become clear th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7e44d563fcee9c231e30421f35eb3b
https://doi.org/10.1158/1538-7445.am2023-4724
https://doi.org/10.1158/1538-7445.am2023-4724
Autor:
Moritz Binder, Terra L. Lasho, Wazim Mohammed Ismail, Nana A. Ben-Crentsil, Jenna A. Fernandez, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Nathalie M. Droin, Eric Solary, Keith D. Robertson, Eric D. Wieben, Eric Padron, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik
Publikováno v:
Cancer Research. 83:806-806
Background: COVID-19 causes significant morbidity and mortality, albeit with considerable heterogeneity among affected individuals. It remains unclear which host factors determine disease severity and survival. Given the propensity of clonal hematopo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197d0613fcd52bc0f85fd7599df62269
https://doi.org/10.1158/1538-7445.am2023-806
https://doi.org/10.1158/1538-7445.am2023-806
Autor:
Seth T. Eisenman, Peter R. Strege, Heather L. Holmes, Simon J. Gibbons, Cheryl E. Bernard, Amelia Mazzone, Maria Gabriela Colmenares Aguilar, Gianrico Farrugia, Michael F. Romero
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 320:G93-G107
In this study, we show that the electrogenic Na+/HCO3− cotransporter, NBCe1/Slc4a4, is expressed in subtypes of interstitial cells of Cajal (ICCs) responsible for electrical slow wave generation throughout the mouse gastrointestinal tract and is ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d23631ee30f0e5c61bb3d42446ddb3
https://doi.org/10.1152/ajpgi.00255.2020
https://doi.org/10.1152/ajpgi.00255.2020