Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Amelia L. Parker"'
Autor:
Elysse C. Filipe, Sipiththa Velayuthar, Ashleigh Philp, Max Nobis, Sharissa L. Latham, Amelia L. Parker, Kendelle J. Murphy, Kaitlin Wyllie, Gretel S. Major, Osvaldo Contreras, Ellie T. Y. Mok, Ronaldo F. Enriquez, Suzanne McGowan, Kristen Feher, Lake‐Ee Quek, Sarah E. Hancock, Michelle Yam, Emmi Tran, Yordanos F. I. Setargew, Joanna N. Skhinas, Jessica L. Chitty, Monica Phimmachanh, Jeremy Z. R. Han, Antonia L. Cadell, Michael Papanicolaou, Hadi Mahmodi, Beata Kiedik, Simon Junankar, Samuel E. Ross, Natasha Lam, Rhiannon Coulson, Jessica Yang, Anaiis Zaratzian, Andrew M. Da Silva, Michael Tayao, Ian L. Chin, Aurélie Cazet, Maya Kansara, Davendra Segara, Andrew Parker, Andrew J. Hoy, Richard P. Harvey, Ozren Bogdanovic, Paul Timpson, David R. Croucher, Elgene Lim, Alexander Swarbrick, Jeff Holst, Nigel Turner, Yu Suk Choi, Irina V. Kabakova, Andrew Philp, Thomas R. Cox
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter stages of the metastatic cascade, such as metast
Externí odkaz:
https://doaj.org/article/9b5a588e6e1648e795ea8f0708ede5c3
Autor:
Amelia L. Parker, Elise Bowman, Adriana Zingone, Brid M. Ryan, Wendy A. Cooper, Maija Kohonen-Corish, Curtis C. Harris, Thomas R. Cox
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-29 (2022)
Abstract Background Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in regulating cell behavior; however, its importance in tumor aggressiv
Externí odkaz:
https://doaj.org/article/33a960bc1cd646fea481743382d365e6
Autor:
Michael Papanicolaou, Amelia L. Parker, Michelle Yam, Elysse C. Filipe, Sunny Z. Wu, Jessica L. Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N. Skhinas, Morghan C. Lucas, David Herrmann, Max Nobis, Brooke A. Pereira, Andrew M. K. Law, Lesley Castillo, Kendelle J. Murphy, Anaiis Zaratzian, Jordan F. Hastings, David R. Croucher, Elgene Lim, Brian G. Oliver, Fatima Valdes Mora, Benjamin L. Parker, David Gallego-Ortega, Alexander Swarbrick, Sandra O’Toole, Paul Timpson, Thomas R. Cox
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The distribution and organisation of matrix molecules in the tumour stroma help shape solid tumour progression. Here they perform temporal proteomic profiling of the matrisome during breast cancer progression and show that collagen XII secreted from
Externí odkaz:
https://doaj.org/article/9576cecfa4d640e3988d0c14e35ac2b3
Autor:
Amelia L. Parker, Leila Toulabi, Takahiro Oike, Yasuyuki Kanke, Daxeshkumar Patel, Takeshi Tada, Sheryse Taylor, Jessica A. Beck, Elise Bowman, Michelle L. Reyzer, Donna Butcher, Skyler Kuhn, Gary T. Pauly, Kristopher W. Krausz, Frank J. Gonzalez, S. Perwez Hussain, Stefan Ambs, Bríd M. Ryan, Xin Wei Wang, Curtis C. Harris
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 14 (2022)
The metabolic dependencies of cancer cells have substantial potential to be exploited to improve the diagnosis and treatment of cancer. Creatine riboside (CR) is identified as a urinary metabolite associated with risk and prognosis in lung and liver
Externí odkaz:
https://doaj.org/article/cade40de76004f3eac0d8228a46781a4
Autor:
Amelia L. Parker, Thomas R. Cox
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The dissemination of tumor cells to local and distant sites presents a significant challenge in the clinical management of many solid tumors. These cells may remain dormant for months or years before overt metastases are re-awakened. The components o
Externí odkaz:
https://doaj.org/article/2ac62e47c45d43f881ffc721fe7ff1cf
Autor:
Amelia L. Parker, Wee Siang Teo, Simon Brayford, Ullhas K. Moorthi, Senthil Arumugam, Charles Ferguson, Robert G. Parton, Joshua A. McCarroll, Maria Kavallaris
Publikováno v:
Cells, Vol 11, Iss 5, p 776 (2022)
βIII-tubulin is a neuronal microtubule protein that is aberrantly expressed in epithelial cancers. The microtubule network is implicated in regulating the architecture and dynamics of the mitochondrial network, although the isotype-specific role for
Externí odkaz:
https://doaj.org/article/8e2982ef91314d80a96294902b9f259a
Autor:
Maria Kavallaris, Frances L. Byrne, Michael S. Shum, Melissa H. Chang, Amelia L. Parker, Lu Yang, Mia C. Akerfeldt, Sharon S. Sagnella, Tanya Dwarte, Marjorie Liu, Rafael B. Erlich, Pei Pei Gan, Joshua A. McCarroll
A) A graph showing a decrease in βIII-tubulin mRNA expression in A549 NSCLC cells stably expressing βIII-tubulin shRNA (pRS/βIIISH61) vs. cells stably expressing control shRNA (pRS/CtrlSH27). B) Representative western blot demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5ccfe0d79bccd93ef2eb198a0a373d
https://doi.org/10.1158/0008-5472.22404861
https://doi.org/10.1158/0008-5472.22404861
Autor:
Maria Kavallaris, Frances L. Byrne, Michael S. Shum, Melissa H. Chang, Amelia L. Parker, Lu Yang, Mia C. Akerfeldt, Sharon S. Sagnella, Tanya Dwarte, Marjorie Liu, Rafael B. Erlich, Pei Pei Gan, Joshua A. McCarroll
βIII-tubulin shRNA NSCLC cells show increased maspin expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca665d185d7b66616d18093ad4536678
https://doi.org/10.1158/0008-5472.22404867
https://doi.org/10.1158/0008-5472.22404867
Autor:
Maria Kavallaris, Frances L. Byrne, Michael S. Shum, Melissa H. Chang, Amelia L. Parker, Lu Yang, Mia C. Akerfeldt, Sharon S. Sagnella, Tanya Dwarte, Marjorie Liu, Rafael B. Erlich, Pei Pei Gan, Joshua A. McCarroll
Validation of proteins found to be differentially expressed in H460 βIII-tubulin shRNA expressing cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7802fc5f060c43152e47f5e073f1a07
https://doi.org/10.1158/0008-5472.22404870.v1
https://doi.org/10.1158/0008-5472.22404870.v1
Autor:
Maria Kavallaris, Frances L. Byrne, Michael S. Shum, Melissa H. Chang, Amelia L. Parker, Lu Yang, Mia C. Akerfeldt, Sharon S. Sagnella, Tanya Dwarte, Marjorie Liu, Rafael B. Erlich, Pei Pei Gan, Joshua A. McCarroll
Suppression of βIII-tubulin increases cell adhesion and decreases cell migration in NSCLC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c63bd5ca9b8efd809dbd6dad930c7fa
https://doi.org/10.1158/0008-5472.22404864.v1
https://doi.org/10.1158/0008-5472.22404864.v1