Výsledky vyhledávání - "Amelia J. Entingh"

Bi-directional Regulation of Brown Fat Adipogenesis by the Insulin Receptor

Autor: C. Ronald Kahn, Amelia J. Entingh, Cullen M. Taniguchi

Publikováno v: Journal of Biological Chemistry. 278:33377-33383

Insulin is a potent inducer of adipogenesis, and differentiation of adipocytes requires many components of the insulin signaling pathway, including the insulin receptor substrate IRS-1 and phosphatidylinositol 3-kinase (PI3K). Brown pre-adipocytes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e992cc735aad8144079ed88bb3784b
https://doi.org/10.1074/jbc.m303056200

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Induction of the C/EBP Homologous Protein (CHOP) by Amino Acid Deprivation Requires Insulin-Like Growth Factor I, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Signaling**This work was supported by NIH Grants CA-42572 and CA-85492. Sequencing was carried out by the DNA Sequencing Shared Resource (Grant P30-CA-68485). Data presentation was performed in part through the use of the Vanderbilt University Medical Center Cell Imaging Resource (Grants CA-68485 and DK-20593)

Autor: Harold L. Moses, Brian K. Law, Amelia J. Entingh

Publikováno v: Endocrinology. 142:221-228

In mammalian cells, gene regulation by amino acid deprivation is poorly understood. Here, we examined the signaling pathways involved in the induction of the C/EBP homologous protein (CHOP) by amino acid starvation. CHOP is a transcription factor tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e75c443ea2071dd9712bd4019d7b42b7
https://doi.org/10.1210/endo.142.1.7906

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Salicylate-induced Growth Arrest Is Associated with Inhibition of p70s6k and Down-regulation of c-Myc, Cyclin D1, Cyclin A, and Proliferating Cell Nuclear Antigen

Autor: Peter Nørgaard, Mary Waltner-Law, Anna Chytil, Mary Aakre, Brian K. Law, Amelia J. Entingh, Harold L. Moses

Publikováno v: Journal of Biological Chemistry. 275:38261-38267

Salicylate and its pro-drug form aspirin are widely used medicinally for their analgesic and anti-inflammatory properties, and more recently for their ability to protect against colon cancer and cardiovascular disease. Despite the wide use of salicyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccccee9fb2ac8bb3a1db81cbb29ce79
https://doi.org/10.1074/jbc.m005545200

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Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

Autor: Aramandala Radhika, Amelia J. Entingh, Bandaru S. Reddy, Raymond N. DuBois

Publikováno v: Gastroenterology. 110:1259-1262

BACKGROUND & AIMS: Multiple studies show that continuous use of nonsteroidal anti-inflammatory drugs (NSAIDs) lowers the risk of colon cancer in humans and carcinogen-treated rodents. One target for NSAIDs is cyclooxygenase (COX), and two isoforms of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebeb7c1e798a0addd97559779fff604
https://doi.org/10.1053/gast.1996.v110.pm8613017

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