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Antibiotic-mediated selection of randomly mutagenized and cytokine-expressing oncolytic viruses.

Autor: Rezaei R; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Boulton S; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Ahmadi M; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada., Petryk J; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Da Silva M; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada., Kooshki Zamani N; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada., Singaravelu R; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., St-Laurent G; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada., Daniel L; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada., Sadeghipour A; Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran., Pelin A; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA., Poutou J; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Munoz Zuniga AI; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada., Choy C; Department of Biochemistry, University of British Columbia, Vancouver, British Columbia, Canada., Gilchrist VH; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada., Khalid Z; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada., Austin B; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Onsu KA; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Marius R; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Ameli Z; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada., Mohammadi F; Department of Biosciences, University of Milan, Milan, Italy., Mancinelli V; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada., Wang E; Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada., Nik-Akhtar A; Ottawa Institute of Systems Biology and Centre for Neuromuscular Disease, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada., Alwithenani A; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Panahi Arasi F; University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Ferguson SSG; University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Department of Neuroscience, Faculty of Health Sciences, Carleton University, Ottawa, Ontario, Canada., Hobman TC; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada.; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada., Alain T; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada., Tai LH; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada.; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada., Ilkow CS; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Diallo JS; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Bell JC; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. Jbell@ohri.ca.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada. Jbell@ohri.ca., Azad T; Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, Québec, Canada. Taha.Azad@USherbrooke.ca.; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada. Taha.Azad@USherbrooke.ca.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.