Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Amel SAOUDI"'
Autor:
Amel Saoudi, Sacha Barberat, Olivier le Coz, Ophélie Vacca, Mathilde Doisy Caquant, Thomas Tensorer, Eric Sliwinski, Luis Garcia, Francesco Muntoni, Cyrille Vaillend, Aurélie Goyenvalle
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 173-188 (2023)
The mdx52 mouse model recapitulates a frequent mutation profile associated with brain involvement in Duchenne muscular dystrophy. Deletion of exon 52 impedes expression of two dystrophins (Dp427, Dp140) expressed in brain, and is eligible for therape
Externí odkaz:
https://doaj.org/article/14cbed576c444c01be01ae87e64766c9
Autor:
Mathilde Doisy, Ophélie Vacca, Claire Fergus, Talia Gileadi, Minou Verhaeg, Amel Saoudi, Thomas Tensorer, Luis Garcia, Vincent P. Kelly, Federica Montanaro, Jennifer E. Morgan, Maaike van Putten, Annemieke Aartsma-Rus, Cyrille Vaillend, Francesco Muntoni, Aurélie Goyenvalle
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3243 (2023)
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene that disrupt the open reading frame and thus prevent production of functional dystrophin proteins. Recent advances in DMD treatment, notably exon skipping and AAV gene therapy,
Externí odkaz:
https://doaj.org/article/29a1434a711345e993444660698a38fe
Publikováno v:
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, Vol 78, Iss 1, Pp 129-134 (2021)
The objective of this study is to reduce the cost of raising beef cattle in Algeria by proposing a Zootechnical fattening protocol for breeders. The study was carried out on mixed-breed young bulls (Charolais x local breeds). Food rations were distri
Externí odkaz:
https://doaj.org/article/12775001f9df4b0e9ed397cd4d7e43fb
Autor:
Amel Saoudi, Claire Fergus, Talia Gileadi, Federica Montanaro, Jennifer E. Morgan, Vincent P. Kelly, Thomas Tensorer, Luis Garcia, Cyrille Vaillend, Francesco Muntoni, Aurélie Goyenvalle
Publikováno v:
Cells, Vol 12, Iss 6, p 908 (2023)
Nucleic acid-based therapies have demonstrated great potential for the treatment of monogenetic diseases, including neurologic disorders. To date, regulatory approval has been received for a dozen antisense oligonucleotides (ASOs); however, these che
Externí odkaz:
https://doaj.org/article/beb2afcd99a94239af7d9e7e2d20f5e8
Autor:
Amel Saoudi, Faouzi Zarrouki, Catherine Sebrié, Charlotte Izabelle, Aurélie Goyenvalle, Cyrille Vaillend
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 9 (2021)
The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients. Deletion of exon 52 impedes expression of several brain dystrophi
Externí odkaz:
https://doaj.org/article/28dee72759884abf88a3d5e1e42ac5d0
Autor:
Mirella Telles Salgueiro Barboni, André Maurício Passos Liber, Anneka Joachimsthaler, Amel Saoudi, Aurélie Goyenvalle, Alvaro Rendon, Jérome E. Roger, Dora Fix Ventura, Jan Kremers, Cyrille Vaillend
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105288- (2021)
The mdx52 mouse model of Duchenne muscular dystrophy (DMD) is lacking exon 52 of the DMD gene that is located in a hotspot mutation region causing cognitive deficits and retinal anomalies in DMD patients. This deletion leads to the loss of the dystro
Externí odkaz:
https://doaj.org/article/172457834efd45038fd22b1f72f68a27
Publikováno v:
DESALINATION AND WATER TREATMENT. 278:72-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3510cfe55f66a376c8cd924d774f3495
https://doi.org/10.5004/dwt.2022.29077
https://doi.org/10.5004/dwt.2022.29077
Autor:
Amel Saoudi, Aurélie Goyenvalle
Publikováno v:
médecine/sciences. 37:625-631
Les avancées en recherches génétique et génomique ne cessent d’accroître nos connaissances des maladies héréditaires. Un nombre croissant de ces maladies relève d’épissages aberrants qui représentent des cibles idéales pour les approch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e71b0815206a18b064f5b91d6c023b5
https://doi.org/10.1051/medsci/2021091
https://doi.org/10.1051/medsci/2021091
Autor:
Cyrille Vaillend, Amel Saoudi, Catherine Sebrié, Aurélie Goyenvalle, Faouzi Zarrouki, Charlotte Izabelle
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, 2021, 14 (9), pp.dmm049028. ⟨10.1242/dmm.049028⟩
Disease Models & Mechanisms, Cambridge Company of Biologists, 2021, 14 (9), pp.dmm049028. ⟨10.1242/dmm.049028⟩
Disease Models & Mechanisms, Vol 14, Iss 9 (2021)
article-version (VoR) Version of Record
Disease Models & Mechanisms, 2021, 14 (9), pp.dmm049028. ⟨10.1242/dmm.049028⟩
Disease Models & Mechanisms, Cambridge Company of Biologists, 2021, 14 (9), pp.dmm049028. ⟨10.1242/dmm.049028⟩
Disease Models & Mechanisms, Vol 14, Iss 9 (2021)
article-version (VoR) Version of Record
The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients. Deletion of exon 52 impedes expression of several brain dystrophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d925b2f297a821e724b3b33ad4221e
https://hal.science/hal-03407894/document
https://hal.science/hal-03407894/document
Autor:
Amel, Saoudi, Aurélie, Goyenvalle
Publikováno v:
Medecine sciences : M/S. 37(6-7)
Advances in genetic and genomic research continue to increase our knowledge of hereditary diseases, and an increasing number of them are being attributed to aberrant splicing, thus representing ideal targets for RNA modulation therapies. New strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abfb68c7dc20883f3a80d6ba93ab707f
https://pubmed.ncbi.nlm.nih.gov/34180822
https://pubmed.ncbi.nlm.nih.gov/34180822