Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Amel, Mettouchi"'
Autor:
Nilmara de Oliveira Alves, Guillaume Dalmasso, Darja Nikitina, Amaury Vaysse, Richard Ruez, Lea Ledoux, Thierry Pedron, Emma Bergsten, Olivier Boulard, Lora Autier, Sofian Allam, Laurence Motreff, Pierre Sauvanet, Diane Letourneur, Pragya Kashyap, Johan Gagnière, Denis Pezet, Catherine Godfraind, Michel Salzet, Emmanuel Lemichez, Mathilde Bonnet, Imène Najjar, Christophe Malabat, Marc Monot, Denis Mestivier, Nicolas Barnich, Pankaj Yadav, Isabelle Fournier, Sean Kennedy, Amel Mettouchi, Richard Bonnet, Iradj Sobhani, Mathias Chamaillard
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTIntratumoral bacteria flexibly contribute to cellular and molecular tumor heterogeneity for supporting cancer recurrence through poorly understood mechanisms. Using spatial metabolomic profiling technologies and 16SrRNA sequencing, we herein
Externí odkaz:
https://doaj.org/article/8c88e5e7aa7c4e8590455a2c80f8cc28
Autor:
Emma Bergsten, Denis Mestivier, Francoise Donnadieu, Thierry Pedron, Caroline Barau, Landry Tsoumtsa Meda, Amel Mettouchi, Emmanuel Lemichez, Olivier Gorgette, Mathias Chamaillard, Amaury Vaysse, Stevenn Volant, Abiba Doukani, Philippe J. Sansonetti, Iradj Sobhani, Giulia Nigro
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTRecently, an intestinal dysbiotic microbiota with enrichment in oral cavity bacteria has been described in colorectal cancer (CRC) patients. Here, we characterize and investigate one of these oral pathobionts, the Gram-positive anaerobic cocc
Externí odkaz:
https://doaj.org/article/a53bd29379ac48b9b5a182a0fab55a31
Autor:
Héloïse Chat, Guillaume Dalmasso, Catherine Godfraind, Virginie Bonnin, Racha Beyrouthy, Mathilde Bonnet, Nicolas Barnich, Amel Mettouchi, Emmanuel Lemichez, Richard Bonnet, Julien Delmas
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTColorectal cancer (CRC) patients are frequently colonized by colibactin-producing Escherichia coli (CoPEC) (>40%), which enhances tumorigenesis in mouse models of CRC. We observed that 50% of CoPEC also contains the cnf1 gene, which encodes c
Externí odkaz:
https://doaj.org/article/33273ddb6eaf44cbbb29365042302a49
Autor:
Serena Petracchini, Daniel Hamaoui, Anne Doye, Atef Asnacios, Florian Fage, Elisa Vitiello, Martial Balland, Sebastien Janel, Frank Lafont, Mukund Gupta, Benoit Ladoux, Jerôme Gilleron, Teresa M. Maia, Francis Impens, Laurent Gagnoux-Palacios, Mads Daugaard, Poul H. Sorensen, Emmanuel Lemichez, Amel Mettouchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al.
Externí odkaz:
https://doaj.org/article/1958110237ff42f391f49c167f39e785
Autor:
Landry L. Tsoumtsa Meda, Luce Landraud, Serena Petracchini, Stéphane Descorps-Declere, Emeline Perthame, Marie-Anne Nahori, Laura Ramirez Finn, Molly A. Ingersoll, Rafael Patiño-Navarrete, Philippe Glaser, Richard Bonnet, Olivier Dussurget, Erick Denamur, Amel Mettouchi, Emmanuel Lemichez
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Epidemiological projections point to acquisition of ever-expanding multidrug resistance (MDR) by Escherichia coli, a commensal of the digestive tract and a source of urinary tract pathogens. Bioinformatics analyses of a large collection of E. coli ge
Externí odkaz:
https://doaj.org/article/de7d105993ef4283a86dca81d2d69b67
Autor:
Yu Wu, Nassim Mahtal, Eléa Paillares, Léa Swistak, Sara Sagadiev, Mridu Acharya, Caroline Demeret, Sylvie Van Der Werf, Florence Guivel-Benhassine, Olivier Schwartz, Serena Petracchini, Amel Mettouchi, Lucie Caramelle, Pierre Couvineau, Robert Thai, Peggy Barbe, Mathilde Keck, Priscille Brodin, Arnaud Machelart, Valentin Sencio, François Trottein, Martin Sachse, Gaëtan Chicanne, Bernard Payrastre, Florian Ville, Victor Kreis, Michel-Robert Popoff, Ludger Johannes, Jean-Christophe Cintrat, Julien Barbier, Daniel Gillet, Emmanuel Lemichez
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104537- (2022)
Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways. Here, we performed a hig
Externí odkaz:
https://doaj.org/article/a1115a643e6e4c1fb159e5c28cc1dc8c
Autor:
Elisa Vitiello, Philippe Moreau, Vanessa Nunes, Amel Mettouchi, Helder Maiato, Jorge G. Ferreira, Irène Wang, Martial Balland
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Centriolar separation is thought to be crucial for centriole duplication, but the mechanism behind separation is poorly understood. Here, using micropatterning, the authors report that actomyosin forces influence the direction, distance, and time of
Externí odkaz:
https://doaj.org/article/65e5c4e2368645a7ad2f6b3e546366e0
Autor:
Frédéric Bost, Jean François Tanti, Olivier Cuvillier, Emmanuel Lemichez, Mireille Cormont, Bernard Malavaud, Frédéric Larbret, Kathiane Laurent, Amel Mettouchi, Fabienne Massa, Muriel Golzio, Isabelle Ader, Béatrice Dirat
Supplemental Figures S1-S12. Figure S1: Metformin does not affect mouse weight an insulinemia; Figure S2: Metformin does not induce apoptosis in prostate cancer cells; Figure S3: Metformin does not affect P69 cell migration; Figure S4: Metformin bloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00baeedb26ef0229ddcba5edaafb6e24
https://doi.org/10.1158/1535-7163.22502803.v1
https://doi.org/10.1158/1535-7163.22502803.v1
Autor:
Nilmara de Oliveira Alves, Olivier Boulard, Amaury Vaysse, Guillaume Dalmasso, Darja Nikitina, Richard Ruez, Thierry Pedron, Emma Bergstein, Pierre Sauvanet, Diane Letourneur, Catherine Godfraind, Imène Najjar, Emmanuel Lemichez, Juan Lucio Iovanna, Denis Mestivier, Nicolas Barnich, Philippe Sansonetti, Christophe Malabat, Marc Monot, Sean Kennedy, Amel Mettouchi, Richard Bonnet, Iradj Sobhani, Mathias Chamaillard
The cellular heterogeneity within a variety of solid tumors is influenced by several type of tumor-associated bacteria through yet poorly understood mechanisms. Unbiased genomic analysis revealed that right-sided colorectal tumors with poorer prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::873d8a58702524150c7b10f8bb1f84eb
https://doi.org/10.1101/2023.03.13.523827
https://doi.org/10.1101/2023.03.13.523827
Autor:
Emma Bergsten, Denis Mestivier, Francoise Donnadieu, Thierry Pedron, Caroline Barau, Landry Tsoumtsa Meda, Amel Mettouchi, Emmanuel Lemichez, Olivier Gorgette, Mathias Chamaillard, Amaury Vaysse, Stevenn Volant, Abiba Doukani, Philippe J. Sansonetti, Iradj Sobhani, Giulia Nigro
SummaryRecently, an intestinal dysbiotic microbiota with enrichment in oral cavity bacteria has been described in colorectal cancer (CRC) patients. Here we characterized and investigated one of these oral pathobionts, the Gram-positive anaerobic cocc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb424da244d889607e2d87b131eaf967
https://doi.org/10.1101/2022.05.14.491935
https://doi.org/10.1101/2022.05.14.491935