Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ameet Guria"'
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
Somatic HLA-I LOH is associated with decreased durable clinical benefit and progression free survival in ICI-treated NSCLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ae8eba790bd7e6d70baa335276b460
https://doi.org/10.1158/2159-8290.22535725.v1
https://doi.org/10.1158/2159-8290.22535725.v1
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
Neoantigen presentation arises as a result of tumor-specific mutations and is a critical component of immune surveillance that can be abrogated by somatic LOH of the human leukocyte antigen class I (HLA-I) locus. To understand the role of HLA-I LOH i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e82d91644d24da5d493cb0d66e86e71
https://doi.org/10.1158/2159-8290.c.6547924.v1
https://doi.org/10.1158/2159-8290.c.6547924.v1
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
Characteristics of patients in the real-world clinico-genomic cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d04d6516cd719ccacceafa013677769
https://doi.org/10.1158/2159-8290.22535713.v1
https://doi.org/10.1158/2159-8290.22535713.v1
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
Sample counts by tumor type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf5f8808d936b37ba87be0bc672d06c
https://doi.org/10.1158/2159-8290.22535710.v1
https://doi.org/10.1158/2159-8290.22535710.v1
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
HLA-I germline zygosity has no impact on patient survival in ICI-treated NSCLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a50f5d76b2ea474d6660659c6ded0ce
https://doi.org/10.1158/2159-8290.22535728
https://doi.org/10.1158/2159-8290.22535728
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
EGFR and ALK mutations used for exclusion in the MSK clinical cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b298ab546aa2d05faf1356215745b6d
https://doi.org/10.1158/2159-8290.22535707.v1
https://doi.org/10.1158/2159-8290.22535707.v1
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
Somatic HLA-I LOH is not significantly enriched in microsatellite instable samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250b9ed78b71a636504f5661cbb9ff13
https://doi.org/10.1158/2159-8290.22535722.v1
https://doi.org/10.1158/2159-8290.22535722.v1
Autor:
Lee A. Albacker, Priti S. Hegde, Garrett M. Frampton, Brian M. Alexander, Naiyer A. Rizvi, Leah A. Comment, David Fabrizio, Gaurav Singal, Alan Braly, Jay A. Moore, Dean C. Pavlick, Ethan S. Sokol, Virginia Fisher, Gerald Li, Max Minker, Ameet Guria, Nora Sanchez, Radwa Sharaf, Dexter X. Jin, Karthikeyan Murugesan, Meagan Montesion
Association of DAXX loss of function mutations and HLA-I LOH in tumor types with low rates of PD-L1 positivity and low TMB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d62010c155f6bd17388aec611df69f1
https://doi.org/10.1158/2159-8290.22535719.v1
https://doi.org/10.1158/2159-8290.22535719.v1
Autor:
Lee A. Albacker, Meagan Montesion, Gerald Li, Ethan Sokol, Virginia Fisher, Alan Braly, Brian M. Alexander, Garrett M. Frampton, Karthikeyan Murugesan, Priti Hegde, David Fabrizio, Dexter X. Jin, Radwa Sharaf, Gaurav Singal, Leah Comment, Naiyer A. Rizvi, Jay A. Moore, Nora Sanchez, Max Minker, Dean Pavlick, Ameet Guria
Publikováno v:
Cancer Discovery. 11:282-292
Neoantigen presentation arises as a result of tumor-specific mutations and is a critical component of immune surveillance that can be abrogated by somatic LOH of the human leukocyte antigen class I (HLA-I) locus. To understand the role of HLA-I LOH i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e502cf55832c289d02f973f457e824
https://doi.org/10.1158/2159-8290.cd-20-0672
https://doi.org/10.1158/2159-8290.cd-20-0672
Autor:
Gerald Li, Thomas Caron, Ann Jaskiw, David Bourque, Kathi Seidl-Rathkopf, Nathan C. Nussbaum, Peter Miller, Allen C. Nunnally, Garrett M. Frampton, Aracelis Z. Torres, Mark Bailey, Shannon Frank, Ezra Baydur, Bryan Bowser, Erik M. Lehnert, Anala Gossai, Vineeta Agarwala, Jie He, Vincent A. Miller, Gaurav Kaushik, Amy P. Abernethy, Dana Feuchtbaum, Gaurav Singal, Ivan Ivanov, Daniel Backenroth, Garrett Alpha-Cobb, Ameet Guria, Claire O'Connell
Publikováno v:
JAMA. 321:1391
Importance Data sets linking comprehensive genomic profiling (CGP) to clinical outcomes may accelerate precision medicine. Objective To assess whether a database that combines EHR-derived clinical data with CGP can identify and extend associations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a71d839a782a7d3f41efb04388f2a467
https://doi.org/10.1001/jama.2019.3241
https://doi.org/10.1001/jama.2019.3241