Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ameesha Batheja"'
Autor:
Cindy Zakszewski, Rao N.V.S. Mamidi, Michael McMillia, Chao Han, Monica Singer, Carlo Sensenhauser, Shannon Dallas, Ameesha Batheja, Honghui Zhou, Jose Silva, Maria Markowska
Publikováno v:
Current Drug Metabolism. 13:923-929
Inflammatory diseases such as rheumatoid arthritis and psoriasis are characterized by increases in circulating cytokines, which play an important role in modulation of the disease state. Several marketed bio-therapeutics target cytokines and act as e
Autor:
Ameesha Batheja, Mathew T. Pletcher, Alison H. Harrill, Paul B. Watkins, Merrie Mosedale, Hong Wu, Catherine L. Kurtz, Rachel J. Church, Susan Sumner, Karamjeet Pandher, Monica Singer, Wimal Pathmasiri, Karissa Adkins, John S. Eaddy
Isoniazid (INH), the mainstay therapeutic for tuberculosis infection, has been associated with rare but serious hepatotoxicity in the clinic. However, the mechanisms underlying inter-individual variability in the response to this drug have remained e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af650f83ece5d45e9d3b1a1aeb60e90
Autor:
Ameesha Batheja, Carlo Sensenhauser, Jose Silva, Monica Singer, Souvik Chattopadhyay, Shannon Dallas
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 41(4)
Psoriasis is a T-cell-mediated autoimmune disease involving the skin. Two cytokines, interleukin-12 (IL-12) and IL-23 have been shown to play a pivotal role in the pathogenesis of the disease. Ustekinumab (Stelara) is a therapeutic monoclonal antibod
Autor:
Bram Van Dijck, Monica Singer, Ann Lampo, Jan Snoeys, Sandra De Jonghe, Kristel Steemans, Nancy Bogdan, Sofie Starckx, Jennifer C. Sasaki, Peggy Guzzie-Peck, Lieve Lammens, Ameesha Batheja, Jacky Van Gompel, Petra Vinken, Geert R. Verheyen
Publikováno v:
Toxicologic pathology. 41(5)
The detection of drug-induced hepatotoxicity remains an important safety issue in drug development. A liver-specific microRNA species, microRNA-122 (miR-122), has recently shown potential for predicting liver injury in addition to the standard hepati
Autor:
Petra Vinken, Sofie Starckx, Geert R. Verheyen, Ameesha Batheja, J. Van Gompel, K. Steemans, Lieve Lammens, S. De Jonghe
Publikováno v:
Toxicology Letters. 205:S71