Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ameera Alsadeq"'
Autor:
Lea Spory, Johannes Zimmermann, Michaela Vossen-Gajcy, Thomas Beder, Lorenz Bastian, Ameera Alsadeq, Dorothee Winterberg, Fotini Vogiatzi, Tim Wirbelauer, Hilal Bhat, Arndt Borkhardt, Sanil Bhatia, Martin Schrappe, Gunnar Cario, Denis M. Schewe, Lennart Lenk
Publikováno v:
HemaSphere, Vol 7, Iss 9, p e945 (2023)
Externí odkaz:
https://doaj.org/article/4121c3b59dfa474f93d735267a543fa8
Autor:
Lennart Lenk, Dorothee Winterberg, Fotini Vogiatzi, Anna Laqua, Lea Spory, Ahmad Mayar, Anna Dietterle, Gina Münch, Christian Vokuhl, Julia Richter, Andrew G. Polson, Thomas Schüler, Ulf D. Kahlert, Matthias Peipp, Thomas Valerius, Martin Schrappe, Gunnar Cario, Hassan Jumaa, Elias Hobeika, Monika Brüggemann, Ameera Alsadeq, Denis M. Schewe
Publikováno v:
HemaSphere, Vol 6, Iss 8, p e754 (2022)
Externí odkaz:
https://doaj.org/article/ee2a0191775641108c609751c3210508
Autor:
Lennart Lenk, Michela Carlet, Fotini Vogiatzi, Lea Spory, Dorothee Winterberg, Antony Cousins, Michaela Vossen-Gajcy, Olta Ibruli, Christian Vokuhl, Gunnar Cario, Omar El Ayoubi, Lisa Kramer, Matthias Ritgen, Monika Brüggemann, Robert Häsler, Martin Schrappe, Stephan Fuhrmann, Christina Halsey, Irmela Jeremias, Elias Hobeika, Hassan Jumaa, Ameera Alsadeq, Denis M. Schewe
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Lenk et al find that the preB cell receptor (preBCR) is associated with infiltration and relapse of acute lymphoblastic leukemia in the central nervous system (CNS). They also show that downregulation of preBCR component CD79a reduces the engraftment
Externí odkaz:
https://doaj.org/article/45d481a21f3e44e49b4f84076c7e9181
Autor:
Hend Abdelrasoul, Anila Vadakumchery, Markus Werner, Lennart Lenk, Ahmad Khadour, Marc Young, Omar El Ayoubi, Fotini Vogiatzi, Markus Krämer, Vera Schmid, Zhengshan Chen, Yasar Yousafzai, Gunnar Cario, Martin Schrappe, Markus Müschen, Christina Halsey, Medhanie A. Mulaw, Denis M. Schewe, Elias Hobeika, Ameera Alsadeq, Hassan Jumaa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Emergence of ABL1 kinase inhibitor resistant clones may cause disease relapse in Philadelphia chromosome-positive acute lymphoblastic leukemia. Here, the authors show interleukin 7 receptor (IL7R) signaling to contribute to this resistance mechanism,
Externí odkaz:
https://doaj.org/article/a25003f7a49e4b7f9022e8001e0418c9
Autor:
Anila Vadakumchery, Hemin Faraidun, Omar El Ayoubi, Issame Outaleb, Vera Schmid, Hend Abdelrasoul, Timm Amendt, Ahmad Khadour, Corinna Setz, Katharina Göhring, Karoline Lodd, Christoffer Hitzing, Alabbas Alkhatib, Mayas Bilal, Julian Benckendorff, Abdul Kader Al Shugri, Cord Herbert Brakebusch, Niklas Engels, Moumita Datta, Elias Hobeika, Ameera Alsadeq, Hassan Jumaa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR. The adaptor protein SLP65 (also known as BLNK) is an important signaling fac
Externí odkaz:
https://doaj.org/article/bba221cfcb304def8ce9db2a80eaa6fd
Autor:
Henning Fedders, Ameera Alsadeq, Juliane Schmäh, Fotini Vogiatzi, Martin Zimmermann, Anja Möricke, Lennart Lenk, Udo zur Stadt, Martin A. Horstmann, Rob Pieters, Martin Schrappe, Martin Stanulla, Gunnar Cario, Denis M. Schewe
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
Externí odkaz:
https://doaj.org/article/d5e390edf0864bd1a889ea39c31e1933
Autor:
Ameera Alsadeq, Denis M. Schewe
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
Externí odkaz:
https://doaj.org/article/6e9a7cd6dc0840d1a27028892e750f3b
Autor:
Ameera Alsadeq, Henning Fedders, Christian Vokuhl, Nele M. Belau, Martin Zimmermann, Tim Wirbelauer, Steffi Spielberg, Michaela Vossen-Gajcy, Gunnar Cario, Martin Schrappe, Denis M. Schewe
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
Central nervous system infiltration and relapse are poorly understood in childhood acute lymphoblastic leukemia. We examined the role of zeta-chain-associated protein kinase 70 in preclinical models of central nervous system leukemia and performed co
Externí odkaz:
https://doaj.org/article/74848867243f4de08c718a8fb2f36bf5
Autor:
Simon Vieth, Thomas Valerius, Christian Kellner, Sophia Rosskopf, Matthias Peipp, Denis M. Schewe, Ameera Alsadeq, Martin Gramatzki, Fabian Meyersieck, Fotini Vogiatzi, Cornelia Sattler, Julia Alten, Martin Schrappe, Lennart Lenk, Gunnar Cario
Publikováno v:
Blood. 130:1543-1552
Antibody therapy constitutes a major advance in the treatment of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). To evaluate the efficacy and the mechanisms of action of CD19 monoclonal antibody therapy in pediatric BCP-ALL, we tested an Fc-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9cf0221021f1933bdf4f2a8adf1818
https://doi.org/10.1182/blood-2017-01-764316
https://doi.org/10.1182/blood-2017-01-764316
Autor:
Ella Levit-Zerdoun, Michael Reth, Elias Hobeika, Roberta Pelanda, Vasiliki Anastasopoulou, Ameera Alsadeq, Roland Pohlmeyer, Marc-Werner Dobenecker, Simon Altmeier
Publikováno v:
The EMBO Journal. 34:925-939
The development and function of B lymphocytes is regulated by numerous signaling pathways, some emanating from the B-cell antigen receptor (BCR). The spleen tyrosine kinase (Syk) plays a central role in the activation of the BCR, but less is known ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d00756a940a2dca41844c17bda3af10
https://doi.org/10.15252/embj.201489732
https://doi.org/10.15252/embj.201489732