Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ameena M Ali"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 263-281 (2019)
Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a major impact in human disease. Such PPIs are potential drugs targets, leading to the need to inhibit/block specific PPIs. While small molecule inhibitor
Externí odkaz:
https://doaj.org/article/5954f963957a435bb2f064d34f1eb4dc
Autor:
Tad A. Holak, Alexander Dömling, Ran Zhang, Constantinos G. Neochoritis, Daniel G. Rivera, Ewa Surmiak, Matthew Groves, Jacek Plewka, Lukasz Skalniak, Beata Labuzek, Ameena M Ali, Manuel G. Ricardo, Jack Atmaj
Publikováno v:
Angewandte Chemie (International ed. in English), 59(13), 5235-5241. WILEY-V C H VERLAG GMBH
Stapled peptides are chemical entities in-between biologics and small molecules, which have proven to be the solution to high affinity protein–protein interaction antagonism, while keeping control over pharmacological performance such as stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0769ba57d31d9c62f8a107a610f30806
https://research.rug.nl/en/publications/1eed797b-c10f-4401-9039-feefae3bb9b6
https://research.rug.nl/en/publications/1eed797b-c10f-4401-9039-feefae3bb9b6
Autor:
S. Mohsen Asghari, Saeed Balalaie, Matthew Groves, Kamran Mansouri, Afsaneh Sadremomtaz, Foroozan Jouyandeh, Razieh Navari, Ameena M Ali, Sylvain Broussy
Publikováno v:
Signal Transduction and Targeted Therapy
Signal transduction and targeted therapy, 5(1):76
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-4 (2020)
Signal transduction and targeted therapy, 5(1):76
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429383a49b073a06d727047347d4dc64
https://pubmed.ncbi.nlm.nih.gov/32499505
https://pubmed.ncbi.nlm.nih.gov/32499505
Autor:
Beata Labuzek, Lukasz Skalniak, Tad A. Holak, Ameena M Ali, Aleksandra Twarda-Clapa, Grzegorz Dubin, Matthew Groves, Sylwia Krzanik, Constantinos G. Neochoritis, Ewa Surmiak, Monika Machula, Alexander Dömling, Aneta Wisniewska
Publikováno v:
The FEBS Journal, 286(7), 1360-1374. NLM (Medline)
The p53 protein is engaged in the repair of DNA mutations and elimination of heavily damaged cells, providing anti-cancer protection. Dysregulation of p53 activity is a crucial step in carcinogenesis. This dysregulation is often caused by the overexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860bf587fa3077f3ae7c510a989a23f3
https://research.rug.nl/en/publications/73613fa3-7146-4637-97c4-48ff108ada19
https://research.rug.nl/en/publications/73613fa3-7146-4637-97c4-48ff108ada19
Autor:
Matthew Groves, Sun Rei Yan, Ameena M Ali, Niels van Oosterwijk, Jack Atmaj, Sergey Lunev, Alaa Adawy, Chris Williams
Publikováno v:
Acta Crystallographica Section F: Structural Biology Communications, 74(Pt 2):ISSN 2053-230X, 76-81. INT UNION CRYSTALLOGRAPHY
Peroxisomes are a major cellular compartment of eukaryotic cells, and are involved in a variety of metabolic functions and pathways according to species, cell type and environmental conditions. Their biogenesis relies on conserved genes known asPEXge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fd3b4706a6be22c511c82156cb3388
https://research.rug.nl/en/publications/d742ed22-da09-4d26-8dcd-5874380562e4
https://research.rug.nl/en/publications/d742ed22-da09-4d26-8dcd-5874380562e4
Autor:
Ameena M Ali, Atsarina L Anindya, Niels van Oosterwijk, Yuanze Wang, Alexander Dömling, Alaa Adawy, Matthew Groves
Publikováno v:
Scientific Reports, 7(1):9355. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Refolding of proteins derived from inclusion bodies is very promising as it can provide a reliable source of target proteins of high purity. However, inclusion body-based protein production is often limited by the lack of techniques for the detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81489c400dabf06d910d15d876db3038
https://research.rug.nl/en/publications/9fb2b8ee-66ea-47f9-ade8-e1507e294e84
https://research.rug.nl/en/publications/9fb2b8ee-66ea-47f9-ade8-e1507e294e84
Autor:
Ameena M Ali
Publikováno v:
Qatar Foundation Annual Research Conference Proceedings Volume 2016 Issue 1.
Introduction: Noninsulin dependent diabetes mellitus (NIDDM) or Diabetes Type 2 is a major health challenge worldwide. In 2014 the World Health Organization (WHO) revealed that the percentage of adults with fasting glucose ≥ 7.0 mmol/L accounts for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14fec2407b6396b099f743f2eb6bfe91
https://doi.org/10.5339/qfarc.2016.hbsp2494
https://doi.org/10.5339/qfarc.2016.hbsp2494