Developmental toxicity assessment of C8 iso acid in CD rats: relevance to embryotoxic aliphatic carboxylic acids.

Autor: Ambroso, J. L., Frank, E. R., Keller, L. H., Trimmer, G. W., Waterman, S. J.

Publikováno v: Toxicological Sciences; Dec1999, Vol. 52 Issue 2, p240-247, 8p, 3 Charts, 2 Graphs

Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid-Mediated DILI.

Autor: Woodhead JL; The Hamner-UNC Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA., Yang K; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Brouwer KL; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Siler SQ; The Hamner-UNC Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA., Stahl SH; DMPK, Drug Safety and Metabolism, AstraZeneca R&D Alderley Park, Macclesfield, UK., Ambroso JL; Safety Assessment, GlaxoSmithKline, Research Triangle Park, North Carolina, USA., Baker D; Investigative Preclinical Toxicology, Safety Assessment, GlaxoSmithKline R&D, Ware, UK., Watkins PB; The Hamner-UNC Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA., Howell BA; The Hamner-UNC Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA.

Publikováno v: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2014 Jul 09; Vol. 3, pp. e123. Date of Electronic Publication: 2014 Jul 09.

Developmental toxicity of di-isodecyl and di-isononyl phthalates in rats.

Autor: Waterman SJ; Exxon Biomedical Sciences, Toxicology Division, East Millstone, NJ 08875, USA. sjwater@fpe.erenj.com, Ambroso JL, Keller LH, Trimmer GW, Nikiforov AI, Harris SB

Publikováno v: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 1999 Mar-Apr; Vol. 13 (2), pp. 131-6.

Fluorometric analysis of endocytosis and lysosomal proteolysis in the rat visceral yolk sac during whole embryo culture.

Autor: Ambroso JL; Department of Environmental and Industrial Health, University of Michigan, Ann Arbor 48109, USA., Larsen SV, Brabec RK, Harris C

Publikováno v: Teratology [Teratology] 1997 Sep; Vol. 56 (3), pp. 201-9.

In vitro embryotoxicity of the cysteine proteinase inhibitors benzyloxycarbonyl-phenylalanine-alanine-diazomethane (Z-Phe-Ala-CHN2) and benzyloxycarbonyl-phenylalanine-phenylalanine-diazomethane (Z-Phe-Phe-CHN2).

Autor: Ambroso JL; Department of Environmental and Industrial Health, University of Michigan, Ann Arbor 48109-2029., Harris C

Publikováno v: Teratology [Teratology] 1994 Sep; Vol. 50 (3), pp. 214-28.