Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A

Autor: Shana Bergman, Rosemary J. Cater, Ambrose Plante, Filippo Mancia, George Khelashvili

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Abstract Major Facilitator Superfamily Domain containing 2 A (MFSD2A) is a transporter that is highly enriched at the blood-brain and blood-retinal barriers, where it mediates Na+-dependent uptake of ω−3 fatty acids in the form of lysolipids into

Externí odkaz: https://doaj.org/article/d3377e0f6cd442c0a87b7f58a95d4be2

Increasing the Difficulty of Automatically Generated Questions via Reinforcement Learning with Synthetic Preference

Autor: Thorne, William, Robinson, Ambrose, Peng, Bohua, Lin, Chenghua, Maynard, Diana

As the cultural heritage sector increasingly adopts technologies like Retrieval-Augmented Generation (RAG) to provide more personalised search experiences and enable conversations with collections data, the demand for specialised evaluation datasets

Externí odkaz: http://arxiv.org/abs/2410.08289

New Measurements of the Deuteron to Proton F2 Structure Function Ratio

Autor: Biswas, Debaditya, Gonzalez, Fernando Araiza, Henry, William, Karki, Abishek, Morean, Casey, Nadeeshani, Sooriyaarachchilage, Sun, Abel, Abrams, Daniel, Ahmed, Zafar, Aljawrneh, Bashar, Alsalmi, Sheren, Ambrose, George, Armstrong, Whitney, Asaturyan, Arshak, Assumin-Gyimah, Kofi, Gayoso, Carlos Ayerbe, Bandari, Anashe, Basnet, Samip, Berdnikov, Vladimir, Bhatt, Hem, Bhetuwal, Deepak, Boeglin, Werner, Bosted, Peter, Brash, Edward, Bukhari, Masroor, Chen, Haoyu, Chen, Jian-Ping, Chen, Mingyu, Christy, Michael Eric, Dusa, Silviu Covrig, Craycraft, Kayla, Danagoulian, Samuel, Day, Donal, Diefenthaler, Markus, Dlamini, Mongi, Dunne, James, Duran, Burcu, Dutta, Dipangkar, Ent, Rolf, Evans, Rory, Fenker, Howard, Fomin, Nadia, Fuchey, Eric, Gaskell, David, Gautam, Thir Narayan, Hansen, Jens-Ole, Hauenstein, Florian, Hernandez, A., Horn, Tanja, Huber, Garth, Jones, Mark, Joosten, Sylvester, Kabir, Md Latiful, Keppel, Cynthia, Khanal, Achyut, King, Paul, Kinney, Edward, Kohl, Michael, Lashley-Colthirst, Nathaniel, Li, Shujie, Li, Wenliang, Liyanage, Anusha Habarakada, Mack, David, Malace, Simona, Markowitz, Pete, Matter, John, Meekins, David, Michaels, Robert, Mkrtchyan, Arthur, Mkrtchyan, Hamlet, Moore, Zae, Nazeer, S. J., Nanda, Shirsendu, Niculescu, Gabriel, Niculescu, Maria, Nguyen, Huong, Nuruzzaman, Nuruzzaman, Pandey, Bishnu, Park, Sanghwa, Pooser, Eric, Puckett, Andrew, Rehfuss, Melanie, Reinhold, Joerg, Sawatzky, Bradley, Smith, G., Szumila-Vance, Holly, Tadepalli, Arun, Tadevosyan, Vardan, Trotta, Richard, Wood, Stephen, Yero, Carlos, Zhang, Jinlong

Nucleon structure functions, as measured in lepton-nucleon scattering, have historically provided a critical observable in the study of partonic dynamics within the nucleon. However, at very large parton momenta it is both experimentally and theoreti

Externí odkaz: http://arxiv.org/abs/2409.15236

Flavor Dependence of Charged Pion Fragmentation Functions

Autor: Bhatt, H., Bosted, P., Jia, S., Armstrong, W., Dutta, D., Ent, R., Gaskell, D., Kinney, E., Mkrtchyan, H., Ali, S., Ambrose, R., Androic, D., Gayoso, C. Ayerbe, Bandari, A., Berdnikov, V., Bhetuwal, D., Biswas, D., Boer, M., Brash, E., Camsonne, A., Chen, J. P., Chen, J., Chen, M., Christy, E. M., Covrig, S., Danagoulian, S., Diefenthaler, M., Duran, B., Elaasar, M., Elliot, C., Fenker, H., Fuchey, E., Hansen, J. O., Hauenstein, F., Horn, T., Huber, G. M., Jones, M. K., Kabir, M. L., Karki, A., Karki, B., Kay, S. J. D., Keppel, C., Kumar, V., Lashley-Colthirst, N., Li, W. B., Mack, D., Malace, S., Markowitz, P., McCaughan, M., McClellan, E., Meekins, D., Michaels, R., Mkrtchyan, A., Niculescu, G., Niculescu, I., Pandey, B., Park, S., Pooser, E., Rehfuss, M., Sawatzky, B., Smith, G. R., Szumila-Vance, H., Tadepalli, A. S., Tadevosyan, V., Trotta, R., Voskanyan, H., Wood, S. A., Ye, Z., Yero, C., Zheng, X.

We have measured the flavor dependence of multiplicities for pi^+ and pi^- production in semi-inclusive deep-inelastic scattering (SIDIS) on proton and deuteron targets to explore a possible charge symmetry violation in fragmentation functions. The e

Externí odkaz: http://arxiv.org/abs/2408.16640

Asymptotics of two-dimensional hydroelastic waves: The zero mass, zero bending limit

Autor: Liu, Shunlian, Ambrose, David M.

We consider two-dimensional hydroelastic waves, in which a free fluid surface separates two fluids of infinite vertical extent. Elastic effects are accounted for at the interface, with a parameter measuring the elastic bending force and another param

Externí odkaz: http://arxiv.org/abs/2406.13288