Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Ambrose A Cheung"'
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Bacterial two-component systems are crucial features of bacterial pathogens such as methicillin-resistant Staphylococcus aureus to overcome environmental and antimicrobial stresses by activating regulons to interfere with the bactericidal me
Externí odkaz:
https://doaj.org/article/bc44db0c2e65456ebe70a8fdfcf4d581
Autor:
Yi Li, Fengli Zhu, Adhar C. Manna, Liang Chen, Jason Jiang, Jong-In Hong, Richard A. Proctor, Arnold S. Bayer, Ambrose L. Cheung, Yan Q. Xiong
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a serious public health threat. We recently demonstrated that the presence of a novel prophage ϕSA169 was associated with vancomycin (VAN) treat
Externí odkaz:
https://doaj.org/article/2ebfbf0b3c694e2b87c6a3abf8df6716
Autor:
Adhar C. Manna, Stefano Leo, Sergey Girel, Víctor González-Ruiz, Serge Rudaz, Patrice Francois, Ambrose L. Cheung
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Staphylococcus aureus adapts to different environments by sensing and responding to diverse environmental cues. The responses are coordinately regulated by regulatory proteins, and small regulatory RNAs at the transcriptional and translation
Externí odkaz:
https://doaj.org/article/c0eeca1600d6438fb9e9617e67146057
Autor:
Sook-Ha Fan, Richard A. Proctor, Selvi C. Ersoy, Adhar C. Manna, Ambrose L. Cheung, Friedrich Götz, Henry F. Chambers, Arnold S. Bayer
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) infections are an increasing concern due to their intrinsic resistance to most standard-of-care β-lactam antibiotics. Recent studies of clinical isolates have documented a novel phenotype,
Externí odkaz:
https://doaj.org/article/c1c2842d93614562ab53cc047089aec1
Autor:
Samuel L. Neff, Thomas H. Hampton, Charles Puerner, Liviu Cengher, Georgia Doing, Alexandra J. Lee, Katja Koeppen, Ambrose L. Cheung, Deborah A. Hogan, Robert A. Cramer, Bruce A. Stanton
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Researchers studying cystic fibrosis (CF) pathogens have produced numerous RNA-seq datasets which are available in the gene expression omnibus (GEO). Although these studies are publicly available, substantial computational expertise and manu
Externí odkaz:
https://doaj.org/article/5e30a2f3c1034ab18bf4061492bd63f8
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0270393 (2022)
Patients with cystic fibrosis (CF) often suffer recurrent bronchial bacterial infections that lead to deterioration of lung function over time. The infections in CF patients are often due to S. aureus and P. aeruginosa that colonize the airways. Sign
Externí odkaz:
https://doaj.org/article/3aa7734af1634366830e69ed7aa5f1c3
Autor:
Liang Li, Yi Li, Fengli Zhu, Ambrose L. Cheung, Genzhu Wang, Guangchun Bai, Richard A. Proctor, Michael R. Yeaman, Arnold S. Bayer, Yan Q. Xiong
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a significant clinically challenging subset of invasive, life-threatening S. aureus infections. We have recently demonstrated that purine biosynt
Externí odkaz:
https://doaj.org/article/1063c77480d04c499e5d906337d3814c
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009338 (2021)
Host defense proteins (HDPs), aka defensins, are a key part of the innate immune system that functions by inserting into the bacterial membranes to form pores to kill invading and colonizing microorganisms. To ensure survival, microorganism such as S
Externí odkaz:
https://doaj.org/article/7d0e317d0d8d464fbcbf55ab1e6f9745
Autor:
Dongzhu Ma, Jonathan B. Mandell, Niles P. Donegan, Ambrose L. Cheung, Wanyan Ma, Scott Rothenberger, Robert M. Q. Shanks, Anthony R. Richardson, Kenneth L. Urish
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Staphylococcus aureus is the major organism responsible for surgical implant infections. Antimicrobial treatment of these infections often fails, leading to expensive surgical intervention and increased risk of mortality to the patient. The
Externí odkaz:
https://doaj.org/article/f0c9f228eed34dbda35ad3ab5c193533
Autor:
Dominique H Limoli, Elizabeth A Warren, Kaitlin D Yarrington, Niles P Donegan, Ambrose L Cheung, George A O'Toole
Publikováno v:
eLife, Vol 8 (2019)
Microbes often live in multispecies communities where interactions among community members impact both the individual constituents and the surrounding environment. Here, we developed a system to visualize interspecies behaviors at initial encounters.
Externí odkaz:
https://doaj.org/article/cbedf9cda54b432198754dd977fd6a92