Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ambra Cappelletto"'
Autor:
Ambra Cappelletto, Edoardo Alfì, Nina Volf, Thi Van Anh Vu, Francesca Bortolotti, Giulio Ciucci, Simone Vodret, Marco Fantuz, Martina Perin, Andrea Colliva, Giacomo Rozzi, Matilde Rossi, Giulia Ruozi, Lorena Zentilin, Roman Vuerich, Daniele Borin, Romano Lapasin, Silvano Piazza, Mattia Chiesa, Daniela Lorizio, Luca Triboli, Sandeep Kumar, Gaia Morello, Claudio Tripodo, Maurizio Pinamonti, Giulia Maria Piperno, Federica Benvenuti, Alessandra Rustighi, Hanjoong Jo, Stefano Piccolo, Giannino Del Sal, Alessandro Carrer, Mauro Giacca, Serena Zacchigna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background New drugs to tackle the next pathway or mutation fueling cancer are constantly proposed, but 97% of them are doomed to fail in clinical trials, largely because they are identified by cellular or in silico screens that cannot predi
Externí odkaz:
https://doaj.org/article/a789156b8a0b44008d091dcfb970d332
Autor:
Ambra Cappelletto, Harriet E. Allan, Marilena Crescente, Edoardo Schneider, Rossana Bussani, Hashim Ali, Ilaria Secco, Simone Vodret, Roberto Simeone, Luca Mascaretti, Serena Zacchigna, Timothy D. Warner, Mauro Giacca
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
Thrombosis of the lung microvasculature is a characteristic of COVID-19 disease, which is observed in large excess compared to other forms of acute respiratory distress syndrome and thus suggests a trigger for thrombosis that is endogenous to the lun
Externí odkaz:
https://doaj.org/article/4d9c6b235b4c46048734a1b26cae79e3
Autor:
Francesca Simoncello, Giulia Maria Piperno, Nicoletta Caronni, Roberto Amadio, Ambra Cappelletto, Giulia Canarutto, Silvano Piazza, Silvio Bicciato, Federica Benvenuti
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Lung tumor-infiltrating neutrophils are known to support growth and dissemination of cancer cells and to suppress T cell responses. However, the precise impact of tissue neutrophils on programming and differentiation of anticancer CD8 T cells in vivo
Externí odkaz:
https://doaj.org/article/3cc3832c6ebb4043a0769d160d0b66d7
Autor:
Anna Di Matteo, Elisa Belloni, Davide Pradella, Ambra Cappelletto, Nina Volf, Serena Zacchigna, Claudia Ghigna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-19 (2020)
Abstract Alternative splicing (AS) is a pervasive molecular process generating multiple protein isoforms, from a single gene. It plays fundamental roles during development, differentiation and maintenance of tissue homeostasis, while aberrant AS is c
Externí odkaz:
https://doaj.org/article/ff0b01acf4e14a90b143c5b7c6634b64
Autor:
Ambra Cappelletto, Serena Zacchigna
Publikováno v:
Vascular Biology, Vol 1, Iss 1, Pp H47-H51 (2019)
Cardiac ischemia is the leading cause of morbidity and mortality in a worldwide epidemic. The progressive understanding of the mechanisms driving new blood vessel formation has led to numerous attempts to revascularize the ischemic heart in animal mo
Externí odkaz:
https://doaj.org/article/a8f94706b9dc4c6bae51e7fd5342258f
Autor:
Michael Rehman, Mauro Giacca, Lorena Zentilin, Nina Volf, Ralf H. Adams, Federica Benvenuti, Ambra Cappelletto, Bin Zhou, Serena Zacchigna, Elena Groppa, Giulia Maria Piperno, Tea Kocijan, Gabriele Zucca, Simone Vodret, Andrea Colliva, Matteo Leban
Publikováno v:
Cardiovasc Res
Aims Cardiac ischaemia does not elicit an efficient angiogenic response. Indeed, lack of surgical revascularization upon myocardial infarction results in cardiomyocyte death, scarring, and loss of contractile function. Clinical trials aimed at induci
Autor:
Ambra Cappelletto, Harriet E. Allan, Marilena Crescente, Edoardo Schneider, Rossana Bussani, Hashim Ali, Ilaria Secco, Simone Vodret, Roberto Simeone, Luca Mascaretti, Serena Zacchigna, Timothy D. Warner, Mauro Giacca
Publikováno v:
Cappelletto, A, Allan, H E, Crescente, M, Schneider, E, Bussani, R, Ali, H, Secco, I, Vodret, S, Mascaretti, L, Zacchigna, S, Warner, T D, Giacca, M & Simeone, R 2022, ' SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity ', Frontiers in Cardiovascular Medicine .
BackgroundThrombosis of the lung micro-vasculature is a characteristic of COVID-19 disease, which is observed in large excess compared to other forms of acute respiratory distress syndrome and thus suggests a trigger for thrombosis endogenous to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a930feb76bb8ef34f8ab108782cddb
https://doi.org/10.1101/2021.12.14.472668
https://doi.org/10.1101/2021.12.14.472668
Autor:
Francesca Simoncello, Silvio Bicciato, Tiziana Battini, Giulia Maria Piperno, Federica Benvenuti, Nicoletta Caronni, Ambra Cappelletto
BackgroundTumor infiltrating neutrophils generally correlates to worst prognosis and refractoriness to immunotherapy yet the complexity and significance of diverse subsets resident in tumor tissues has just begun to emerge. In lung tumors, a network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::076a0c3b98f6ecdbf15562f329a74a3d
https://doi.org/10.1101/2021.10.21.464997
https://doi.org/10.1101/2021.10.21.464997
Autor:
Mathilde Cohen-Tannoudji, Ambra Cappelletto, Thomas Voit, Benoit Giroux, Arnaud Ferry, Corinne Bos, Martine Barkats, Marianne Roda, Stéphanie Astord, Thibaut Marais, Maria Grazia Biferi
One of the most promising therapeutic approaches for familial amyotrophic lateral sclerosis linked to superoxide dismutase 1 (SOD1) is the suppression of toxic mutant SOD1 in the affected tissues. Here, we report an innovative molecular strategy for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ecd1299b94cd3af0ae1f9d9d9fe60c
https://europepmc.org/articles/PMC5589057/
https://europepmc.org/articles/PMC5589057/