A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone.

Autor: Hahn CN; Department of Molecular Pathology, SA Pathology, Adelaide, Australia.; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Medicine, University of Adelaide, Adelaide, Australia.; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia., Ross DM; School of Medicine, University of Adelaide, Adelaide, Australia.; Department of Haematology, SA Pathology, Adelaide, Australia.; Flinders University and Medical Centre, Adelaide, Australia., Feng J; ACRF South Australian Cancer Genomics Facility, Centre for Cancer Biology, SA Pathology, Adelaide, Australia., Beligaswatte A; Department of Haematology, SA Pathology, Adelaide, Australia.; Flinders University and Medical Centre, Adelaide, Australia., Hiwase DK; Department of Haematology, SA Pathology, Adelaide, Australia., Parker WT; Department of Molecular Pathology, SA Pathology, Adelaide, Australia.; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia., Ho M; Department of Molecular Pathology, SA Pathology, Adelaide, Australia., Zawitkowski M; Department of Molecular Pathology, SA Pathology, Adelaide, Australia., Ambler KL; Department of Molecular Pathology, SA Pathology, Adelaide, Australia., Cheetham GD; Department of Molecular Pathology, SA Pathology, Adelaide, Australia., Lee YK; Department of Molecular Pathology, SA Pathology, Adelaide, Australia., Babic M; Department of Molecular Pathology, SA Pathology, Adelaide, Australia., Butcher CM; Department of Haematology, SA Pathology, Adelaide, Australia., Engler GA; Department of Haematology, SA Pathology, Adelaide, Australia., Brown AL; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.; Department of Haematology, SA Pathology, Adelaide, Australia., D'Andrea RJ; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.; Department of Haematology, SA Pathology, Adelaide, Australia., Lewis ID; School of Medicine, University of Adelaide, Adelaide, Australia.; Department of Haematology, SA Pathology, Adelaide, Australia., Schreiber AW; ACRF South Australian Cancer Genomics Facility, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia., To LB; School of Medicine, University of Adelaide, Adelaide, Australia.; Department of Haematology, SA Pathology, Adelaide, Australia., Scott HS; Department of Molecular Pathology, SA Pathology, Adelaide, Australia.; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Medicine, University of Adelaide, Adelaide, Australia.; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.; School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia.

Publikováno v: Leukemia [Leukemia] 2015 Oct; Vol. 29 (10), pp. 2101-4. Date of Electronic Publication: 2015 Mar 09.