Výsledky vyhledávání - "Ambika Jaswal"

Akademický článek

Preclinical Evaluation of a Potential GSH Ester Based PET/SPECT Imaging Probe DT(GSHMe)₂ to Detect Gamma Glutamyl Transferase Over Expressing Tumors.

Autor: Harleen Khurana, Virendra Kumar Meena, Surbhi Prakash, Krishna Chuttani, Nidhi Chadha, Ambika Jaswal, Devinder Kumar Dhawan, Anil Kumar Mishra, Puja Panwar Hazari

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0134281 (2015)

Gamma Glutamyl Transferase (GGT) is an important biomarker in malignant cancers. The redox processes ensuing from GGT-mediated metabolism of extracellular GSH are implicated in critical aspects of tumor cell biology. Reportedly, Glutathione monoethyl

Externí odkaz: https://doaj.org/article/96682e9fda45492db28a4a0ae154769f

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The diagnostic performance of 99mTc-methionine single-photon emission tomography in grading glioma preoperatively: a comparison with histopathology and Ki-67 indices

Autor: Baljinder Singh, Puja Panwar Hazari, Bishan D. Radotra, Rajesh Chhabra, Ambika Jaswal, Narendra Kumar, S. K. Gupta, Nisha Rani, Paramjit Singh, Anil Mishra

Publikováno v: Nuclear medicine communications. 41(9)

OBJECTIVE To characterize glioma preoperatively using quantitative 99mTc-methionine SPECT and comparison with MR-perfusion/spectroscopy and histopatholgical/Ki-67 scoring. METHODS Twenty-nine patients (21M: 8F; mean age 42.3 ± 10.5 years) with clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff33d22d64f476e6bfe90434c0fc0ce
https://pubmed.ncbi.nlm.nih.gov/32796472

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Biotinidase Resistant 68Gallium-Radioligand Based on Biotin/Avidin Interaction for Pretargeting: Synthesis and Preclinical Evaluation

Autor: Ambika Jaswal, Harleen Khurana, Puja Panwar Hazari, Shrikant Kukreti, Virendra Kumar Meena, Surbhi Prakash, Anil K. Mishra

Publikováno v: Bioconjugate Chemistry. 27:2780-2790

A new macrocyclic system 2,2′-(12-amino-11,13-dioxo-1,4,7,10-tetraazacyclotridecane-4,7-diyl)diacetic acid (ATRIDAT) was designed for coordinating metals in +2 and +3 oxidation states particularly 68Ga(III), for PET imaging. ATRIDAT was conjugated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73f6b63740b639fea26aab6df008951a
https://doi.org/10.1021/acs.bioconjchem.6b00576

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68Ga-Labeled bismacrocyclic methylene phosphonate as potential bone seeking PET radiopharmaceutical

Autor: Garima Mann, Himanshu Ojha, Ambika Jaswal, Anil Mishra, Anupama Datta, Kanchan Chauhan

Publikováno v: Bioorganic Chemistry. 104:104185

Phosphonates-based agents are well-known bone-seeking radiopharmaceuticals with application in detection and therapy. With higher sensitivity and resolution offered by Positron Emission Tomography (PET), tracers based on this technique are gaining hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32c80e7dd11771cc8acb74865ff748de
https://doi.org/10.1016/j.bioorg.2020.104185

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[68Ga]/[188Re] Complexed [CDTMP] Trans-1,2-Cyclohexyldinitrilotetraphosphonic Acid As a Theranostic Agent for Skeletal Metastases

Autor: Surbhi Prakash, Puja Panwar Hazari, Ambika Jaswal, Anil K. Mishra, Virendra Kumar Meena, Baljinder Singh, Ankita Pandey

Publikováno v: Frontiers in Medicine, Vol 4 (2017)
Frontiers in Medicine

Objective: Metastasis of the osseous tissue is one of the frequent and severe aggravations as a result of several neoplastic conditions, metabolic disorders, infections and cancer. The objective of this study was to evaluate the pertinence of [68Ga]-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644943fc10e2bf5c574e44ee6216e7ab
https://doi.org/10.3389/fmed.2017.00072

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Biotinidase Resistant

Autor: Surbhi, Prakash, Puja Panwar, Hazari, Virendra Kumar, Meena, Ambika, Jaswal, Harleen, Khurana, Shrikant, Kukreti, Anil Kumar, Mishra

Publikováno v: Bioconjugate chemistry. 27(11)

A new macrocyclic system 2,2'-(12-amino-11,13-dioxo-1,4,7,10-tetraazacyclotridecane-4,7-diyl)diacetic acid (ATRIDAT) was designed for coordinating metals in +2 and +3 oxidation states particularly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc70aa2ac0301b9ff7273e59ca3b7056
https://pubmed.ncbi.nlm.nih.gov/27723977

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Clinical efficacy of indigenously developed 99mtc-methionine brain spect in the diagnostic work of glioma in comparision with dynamic susceptibility contrast enhanced MRI

Autor: Nisha Rani, Anil K. Mishra, A. Kohli, Ambika Jaswal, Baljinder Singh, Pawan K. Singh, S. K. Gupta, P. Hazari Puja, Anish Bhattacharya, Manoj Kumar, Narsingh Kumar

Publikováno v: Journal of the Neurological Sciences. 381:172

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46116f36cfc22c0b2125722745aecfee
https://doi.org/10.1016/j.jns.2017.08.500

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LAT1 targeted delivery of methionine based imaging probe derived from M(III) metal ions for early diagnosis of proliferating tumours using molecular imaging modalities

Autor: Harleen Khurana, Surbhi Prakash, Anil K. Mishra, Puja Panwar Hazari, Ambika Jaswal, Surabhi Kirti Mishra, Hemanth Kumar Bhonsle, Virendra Kumar Meena, Lokendra Singh

Publikováno v: Current cancer drug targets. 14(9)

We investigated the potential of DTPA-bis(Methionine), a target specific amino acid based probe for detection of L-type amino acid transporters (LAT1) known to over express in proliferating tumours using multimodality imaging. The ligand, DTPA-bis(Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6512066111d6442d23a37cf8bc22b6
https://pubmed.ncbi.nlm.nih.gov/25329672

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