Výsledky vyhledávání - "Amber Willbanks"

Akademický článek

Autor: Sarah Heerboth, Genevieve Housman, Meghan Leary, Mckenna Longacre, Shannon Byler, Karolina Lapinska, Amber Willbanks, Sibaji Sarkar

Publikováno v: Clinical and Translational Medicine, Vol 4, Iss 1, Pp n/a-n/a (2015)

AbstractEMT and MET comprise the processes by which cells transit between epithelial and mesenchymal states, and they play integral roles in both normal development and cancer metastasis. This article reviews these processes and the molecular pathway

Externí odkaz: https://doaj.org/article/33b9069abe1243d6a712a262304a6233

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Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia

Publikováno v: Clin Cancer Res

Purpose: Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this highly letha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4965dc8589c625fbddc3c8c3a67105d
https://doi.org/10.1158/1078-0432.ccr-22-0445

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Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia

Purpose:Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this highly lethal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cca7d72d22cb5142304ceb7e57dcd31
https://doi.org/10.1158/1078-0432.c.6532413

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Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia

Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731a53f048e0540b003f013e7c7a114a
https://doi.org/10.1158/1078-0432.22486905

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Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia

Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047ed3f87ca8bedb36f7428af682f52d
https://doi.org/10.1158/1078-0432.22486902

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Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women

Autor: William M. Grady, Jean de Dieu Tapsoba, Ming Yu, Ching-Yun Wang, Catherine Duggan, Anne McTiernan, Amber Willbanks

Publikováno v: Epigenetics. 17:1070-1079

Physical activity reduces risk of colon cancer persons by 20-30%. Aberrant methylation patterns are common epigenetic alterations in colorectal adenomas and cancers, and play a role in cancer initiation and progression. Alterations have been identifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee51ed778a3b802087a88ec6fa7050a0
https://doi.org/10.1080/15592294.2021.1982512

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RNA Epigenetics: Fine-Tuning Chromatin Plasticity and Transcriptional Regulation and the Implications in Human Diseases

Autor: Amber Willbanks, Shaun Wood, Jason X. Cheng

Publikováno v: Genes, Vol 12, Iss 627, p 627 (2021)
Genes

Chromatin structure plays an essential role in eukaryotic gene expression and cell identity. Traditionally, DNA and histone modifications have been the focus of chromatin regulation; however, recent molecular and imaging studies have revealed an inti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558a4c186527ce4714ec6bc095720cf9
https://www.mdpi.com/2073-4425/12/5/627

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The Role of RNA Modifications and RNA-modifying Proteins in Cancer Therapy and Drug Resistance

Autor: Amber Willbanks, Shaun Wood, Jason X. Cheng

Publikováno v: Current cancer drug targets. 21(4)

The advent of new genome-wide sequencing technologies has uncovered abnormal RNA modifications and RNA editing in a variety of human cancers. The discovery of reversible RNA N6-methyladenosine (RNA: m6A) by fat mass and obesity-associated protein (FT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da7061ebf038d668a5cce46ebd6f847
https://pubmed.ncbi.nlm.nih.gov/33504307

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Rapid Analysis and Prediction of Drug Resistance in Leukemia By Novel Nascent RNA-Driven Flow Imaging Technologies and Biomarkers

Autor: Amber Willbanks, Shaun Wood, Jason X. Cheng

Publikováno v: Blood. 138:2242-2242

Background: Drug selectivity and resistance is a major obstacle to successful cancer therapy, including traditional chemotherapies (Vasan, N. et al. Nature 2019), immunotherapy (Hu-Lieskovan, S. et al. Future Oncol, 2021), and epigenetic therapy (Sal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0ba3f595e0fad8eefdc0d4aa19ab660
https://doi.org/10.1182/blood-2021-149143

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RNA Cytosine Methyltransferases NSUN1 and NSUN2 Mediate the Lineage-Associated Resistance to Venetoclax in Leukemia

Autor: Shaun Wood, Amber Willbanks, Jason X. Cheng

Publikováno v: Blood. 136:13-14

Background: Combinations of venetoclax/ABT-199, a small molecule that selectively inhibits anti-apoptotic protein BCL2, with hypomethylating agents (HMAs), such as 5-azacytidine (5-AZA, azacidtine) and decitabine have demonstrated remarkable synergis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d295386998b6c72aadebf692fc788ed5
https://doi.org/10.1182/blood-2020-141684

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